Hasil Filter

11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11778)

Halaman 201 / 236
Serelaxin DB05794
biotech | CAS: 99489-94-8

Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It is a heterodimer protein secret…

Kategori:
Cardiac TherapyVasodilators Used in Cardiac Diseases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seribantumab DB11857
biotech | CAS: 1334296-12-6

Seribantumab has been used in trials studying the treatment of NSCLC, Heregulin, Adenocarcinoma, Colorectal Cancer, and Solid Tumor Cancers, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Serinus canaria feather Approved DB10857
biotech

Canary feather is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Serlopitant DB12973
small molecule | CAS: 860642-69-9

Serlopitant has been investigated for the treatment of Prurigo Nodularis.

Kategori:
Heterocyclic Compounds, Fused-RingNeurokinin-1 Receptor AntagonistsNeurotransmitter Agents
Target Protein:
Substance-P receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sermorelin Approved DB00010
biotech | CAS: 86168-78-7

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid r…

Kategori:
Amino Acids, Peptides, and ProteinsAnterior Pituitary Lobe Hormones and AnaloguesDiagnostic Agents +13
Target Protein:
Growth hormone-releasing hormone receptor
Waktu Paruh11-12 min
Vol. Distribusi-
Klirens-
Genetik -
Serotonin DB08839
small molecule | CAS: 50-67-9

For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.

Kategori:
AminesAntidepressive AgentsAutacoids +19
Target Protein:
5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 75-hydroxytryptamine receptor 2B +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SerpinPC DB17698
biotech

SerpinPC is a mutated alpha-1-antitrypsin (?1AT) and serine protease inhibitor being investigated for the treatment of hemophilia.[A258993]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Serplulimab DB17451
biotech | CAS: 2231029-82-4

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsMonoclonal antibodies and antibody drug conjugates +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Serrapeptase DB13131
biotech | CAS: 95077-02-4

Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections. Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of …

Kategori:
AnalgesicsAnalgesics, Non-NarcoticAnti-Inflammatory Agents +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sertraline Approved DB01104
small molecule | CAS: 79617-96-2

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSR…

Kategori:
Agents that reduce seizure thresholdAminesAntidepressive Agents +39
Target Protein:
Sodium-dependent serotonin transporterSodium-dependent dopamine transporterSigma receptor +2
Gen Terkait:
CYP2C19 CYP2C19
Waktu ParuhThe elimination hal…
Vol. DistribusiSertraline is widel…
KlirensIn pharmacokinetic …
Genetik 2 Varian
Sesame oil DB11172
biotech | CAS: 8008-74-0

Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic acid, stearic acid and other fatty acids. Sesame oil is reported to po…

Kategori:
Biological ProductsComplex MixturesDiet, Food, and Nutrition +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2379806-98-9

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Setanaxib DB16869
small molecule | CAS: 1218942-37-0

Deskripsi belum tersedia.

Kategori:
PyrazolesPyridines
Target Protein:
NADPH oxidase 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Setiptiline DB09304
small molecule | CAS: 57262-94-9

Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.

Kategori:
Antidepressive Agents, TetracyclicDibenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Alpha-2 adrenergic receptorsSerotonin Receptors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Setmelanotide Approved DB11700
small molecule | CAS: 920014-72-8

Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies.[L24474] It is an agonist of the melanocortin 4 receptor.[A224449] Earlier attempts at agonizing MC4R (such as LY2…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsAnti-Obesity Agents +19
Target Protein:
Melanocortin receptor 4
Waktu ParuhThe elimination had…
Vol. DistribusiThe apparent volume…
KlirensA 3mg subcutaneous …
Genetik -
Setogepram DB15447
small molecule | CAS: 1002101-19-0

Setogepram is under investigation in clinical trial NCT03184584 (Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Target Protein:
G-protein coupled receptor 84Free fatty acid receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Setrobuvir DB12051
small molecule | CAS: 1071517-39-9

Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolinesSulfonamides +2
Target Protein:
Genome polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Setrusumab DB14778
biotech | CAS: 1847394-95-9

Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sevasemten DB18983
small molecule | CAS: 2417395-15-2

Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sevelamer Approved DB00658
small molecule | CAS: 52757-95-6

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.

Kategori:
AminesBile Acid SequestrantsChelating Agents +9
Target Protein:
Phosphate
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seviprotimut-L DB16328
biotech

Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sevirumab DB17771
biotech | CAS: 138660-96-5

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seviteronel DB12275
small molecule | CAS: 1610537-15-9

Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.

Kategori:
Antineoplastic AgentsCytochrome P-450 Enzyme InhibitorsEnzyme Inhibitors
Target Protein:
Steroid 17-alpha-hydroxylase/17,20 lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sevoflurane Approved DB01236
small molecule | CAS: 28523-86-6

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia.[L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient.[L42340] Sevoflurane was patented in 1972, w…

Kategori:
Agents that produce hypertensionAnestheticsAnesthetics, General +17
Target Protein:
GABA(A) ReceptorGlycine receptor subunit alpha-1Glutamate receptor 1 +3
Waktu ParuhThe terminal elimin…
Vol. DistribusiPatients given low-…
KlirensIn patients given l…
Genetik -
Sevuparin DB15007
small molecule

Sevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin).

Kategori:
CarbohydratesGlycosaminoglycansPolysaccharides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SGI-1776 DB12494
small molecule | CAS: 1025065-69-3

SGI-1776 has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SGN-30 DB05471
biotech

SGN-30 is an engineered monoclonal antibody (mAb) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of hematologic malignancies as compared to on normal cells. SGN-30 has been shown to induce direct anti-cancer…

Target Protein:
Nuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SGN-B6A DB18377
biotech | CAS: 2764774-91-4

Sigvotatug vedotin (SGN-B6A) is a humanized immunoglobulin G1 anti-integrin beta-6 monoclonal antibody conjugated to monomethyl auristatin E.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SGS-742 DB05010
small molecule | CAS: 123690-78-8

SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.

Kategori:
Central Nervous System AgentsCompounds used in a research, industrial, or household settingGABA Agents +4
Target Protein:
Gamma-aminobutyric acid type B receptor subunit 1Gamma-aminobutyric acid type B receptor subunit 2
Waktu Paruh4 hours
Vol. Distribusi-
Klirens-
Genetik -
SGX-523 DB06314
small molecule | CAS: 1022150-57-7

A MET receptor tyrosine kinase inhibitor.

Target Protein:
Hepatocyte growth factor receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SHR-A1904 DB18702
biotech

SHR-A1904 is under investigation in clinical trial NCT04877717 (A Study of SHR-A1904 in Patients With Advanced Solid Cancer).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Shrimp Approved DB10567
biotech

Shrimp allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sibeprenlimab DB18919
biotech | CAS: 2382896-07-1

Sibeprenlimab is under investigation in clinical trial NCT05248659 (Phase 2/3 Open-label Trial of Sibeprenlimab in the Treatment of Immunoglobulin a Nephropathy).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sibrotuzumab DB06474
biotech

Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Prolyl endopeptidase FAP
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sifalimumab DB12773
biotech | CAS: 1006877-41-3

Sifalimumab is a fully human monoclonal antibody targeting interferon-alpha. The levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disea…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Interferon alpha-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SIG-001 DB17826
biotech

SIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer modified alginate spheres.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SIG-007 DB17710
biotech

SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A. Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.[L46153]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SIG-207 DB18547
biotech

SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified alginate spheres

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
siG12D LODER DB16329
biotech

siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Silanol Approved DB11343
small molecule | CAS: 70131-67-8

Silanol is an FDA-approved food contact substance that is commonly used in organosilicon chemistry and silicate mineralogy.

Kategori:
Silicon Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sildenafil Approved DB00203
small molecule | CAS: 139755-83-2

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The …

Kategori:
Agents Causing Muscle ToxicityAmidesCardiovascular Agents +33
Target Protein:
Plasma protease C1 inhibitorcGMP-specific 3',5'-cyclic phosphodiesteraseRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma +3
Gen Terkait:
ACE GNB3
Waktu ParuhThe terminal phase …
Vol. DistribusiThe mean steady-sta…
KlirensThe total body clea…
Genetik 2 Varian
Silibinin DB09298
small molecule | CAS: 22888-70-6

Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of …

Kategori:
Alimentary Tract and MetabolismAntineoplastic AgentsAntineoplastic Agents, Phytogenic +20
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 68611-44-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Silicon Approved DB12982
small molecule | CAS: 7440-21-3

Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).

Kategori:
Diet, Food, and NutritionElementsFood +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Silicon dioxide Approved DB11132
small molecule | CAS: 7631-86-9

Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is tox…

Kategori:
ColloidsComplex MixturesCompounds used in a research, industrial, or household setting +6
Target Protein:
Macrophage receptor MARCO
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Silodosin Approved DB06207
small molecule | CAS: 160970-54-7

Silodosin is a selective antagonist of alpha(?)-1 adrenergic receptors that binds to the ?<sub>1A</sub> subtype with the highest affinity. ?1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the ?<sub>1A</…

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +15
Target Protein:
Alpha-1A adrenergic receptorAlpha-1D adrenergic receptorAlpha-1B adrenergic receptor +1
Waktu ParuhThe elimination hal…
Vol. DistribusiSilodosin has an ap…
KlirensAfter intravenous a…
Genetik -
Silodrate Approved DB14116
small molecule | CAS: 12408-47-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Silver Approved DB12965
small molecule | CAS: 7440-22-4

Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and minera…

Kategori:
Antiseptics and DisinfectantsDermatologicalsElements +4
Target Protein:
MetallothioneinCeruloplasminAlbumin +1
Waktu ParuhThe biological half…
Vol. DistribusiFollowing exposure …
Klirens-
Genetik -
Silver cation DB14521
small molecule | CAS: 14701-21-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 10001–10050 dari 11778
Sebelumnya Halaman 201 / 236 Berikutnya