Digital Pharmacy - Dashboard Peneliti

N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE DB07839

small molecule

Deskripsi belum tersedia.

Target Protein:

Cathepsin S

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N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine DB07382

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase/endoribonuclease IRE1

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N~2~-Succinylornithine DB03582

small molecule

Deskripsi belum tersedia.

Target Protein:

N-succinylarginine dihydrolase

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N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE DB07571

small molecule

Deskripsi belum tersedia.

Target Protein:

ATP-dependent Clp protease proteolytic subunit

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N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE DB07284

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-BENZYLPYRIDINE-2,3-DIAMINE DB07281

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE DB07993

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE DB07303

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE DB07994

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine DB08519

small molecule

Deskripsi belum tersedia.

Target Protein:

Vascular endothelial growth factor receptor 2

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N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine DB08042

small molecule

Deskripsi belum tersedia.

Target Protein:

Vascular endothelial growth factor receptor 2

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O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID DB08762

small molecule

Deskripsi belum tersedia.

Target Protein:

Carboxypeptidase A1

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O-(N-acetyl-alpha-D-galactosaminyl)-L-serine DB02397

small molecule | CAS: 67262-86-6

Deskripsi belum tersedia.

Kategori:

AntigensAntigens, NeoplasmBiological Factors +3

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O-acetyl-L-serine DB01837

small molecule | CAS: 5147-00-2

Deskripsi belum tersedia.

Target Protein:

Prostaglandin G/H synthase 1

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o-Bromophenol DB04586

small molecule | CAS: 95-56-7

Deskripsi belum tersedia.

Kategori:

Benzene Derivatives

Target Protein:

Thymidylate synthaseThymidylate synthase

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o-Cymen-5-ol DB15901

small molecule | CAS: 3228-02-2

Deskripsi belum tersedia.

Kategori:

Benzene Derivatives

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O-Succinylbenzoate DB02251

small molecule | CAS: 27415-09-4

Deskripsi belum tersedia.

Kategori:

Acids, Carbocyclic

Target Protein:

o-succinylbenzoate synthaseo-succinylbenzoate synthaseo-succinylbenzoate synthase

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O-Trifluoromethylphenyl Anthranilic Acid DB02179

small molecule

Deskripsi belum tersedia.

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-bromophenyl)thiocarbamate DB08281

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-chlorophenyl)thiocarbamate DB08282

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamate DB08284

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O1-Pentyl-Mannose DB02695

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyanovirin-N

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O2-Sulfo-Glucuronic Acid DB02264

small molecule

Deskripsi belum tersedia.

Target Protein:

Fibroblast growth factor 1Hepatocyte growth factorHeparan sulfate glucosamine 3-O-sulfotransferase 3A1 +1

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O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL DB04770

small molecule

Deskripsi belum tersedia.

Target Protein:

Pyridoxal kinase

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O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE DB07126

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase Chk1Glycogen synthase kinase-3 betaCyclin-dependent kinase 4 +2

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OAV201 DB17842

biotech

OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated…

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OAV401 DB18254

biotech

Deskripsi belum tersedia.

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Obatoclax DB12191

small molecule | CAS: 803712-67-6

Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.

Kategori:

Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring

Target Protein:

Apoptosis regulator Bcl-2Induced myeloid leukemia cell differentiation protein Mcl-1Bcl-2-like protein 1

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Obecabtagene autoleucel Approved DB17362

biotech

Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.

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Obeldesivir DB18821

small molecule | CAS: 2647441-36-7

Deskripsi belum tersedia.

Kategori:

Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4

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Obeticholic acid Approved DB05990

small molecule | CAS: 459789-99-2

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.[A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to…

Kategori:

Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +14

Target Protein:

Bile acid receptor

Waktu ParuhThe biological half…

Vol. DistribusiThe volume of distr…

KlirensClearance informati…

Genetik -

Obexelimab DB15032

biotech | CAS: 1690307-05-1

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

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OBI-3424 DB16057

small molecule | CAS: 2097713-68-1

OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL)).

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OBI-833 DB19270

biotech | CAS: 2142641-90-3

Deskripsi belum tersedia.

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OBI-888 DB18289

biotech | CAS: 2227156-40-1

Deskripsi belum tersedia.

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Obicetrapib DB14890

small molecule | CAS: 866399-87-3

Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).

Kategori:

Heterocyclic Compounds, Fused-Ring

Target Protein:

Cholesteryl ester transfer protein

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Obinutuzumab Approved DB08935

biotech | CAS: 949142-50-1

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is …

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +20

Target Protein:

B-lymphocyte antigen CD20

Waktu ParuhThe half life of ob…

Vol. DistribusiObinutuzumab has a …

KlirensThe clearance of ob…

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OBP-801 DB12279

small molecule | CAS: 328548-11-4

OBP-801 has been used in trials studying the treatment of Solid Tumor.

Kategori:

Amino Acids, Peptides, and ProteinsAntineoplastic AgentsHistone Deacetylase Inhibitors +2

Target Protein:

Histone deacetylase 1

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OC-1012 DB05834

small molecule

OC-1012 is a compound which has emerged as a promising therapeutic agent for the treatment and prevention of mucositis, a serious side effect of chemotherapy and head and neck radiation therapy.

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OC-459 DB11900

small molecule | CAS: 851723-84-7

OC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.

Kategori:

Heterocyclic Compounds, Fused-RingIndoles

Target Protein:

Prostaglandin D2 receptor 2

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Ocaperidone DB06229

small molecule | CAS: 129029-23-8

Deskripsi belum tersedia.

Kategori:

Pyrimidines

Target Protein:

5-hydroxytryptamine receptor 2AD(2) dopamine receptorHistamine H1 receptor +8

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Ocaratuzumab DB17359

biotech | CAS: 1169956-08-4

Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6

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OCE-205 DB17617

biotech

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and Proteins

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Ochromycinone DB15644

small molecule | CAS: 28882-53-3

Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).

Kategori:

AnthracenesQuinones

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Ocifisertib DB18746

small molecule | CAS: 1338806-73-7

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingPyrazoles

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Ocimum tenuiflorum top Approved DB14273

biotech

Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Ocinaplon DB06529

small molecule | CAS: 96604-21-6

Deskripsi belum tersedia.

Kategori:

Central Nervous System DepressantsHypnotics (Nonbenzodiazepine)Hypnotics and Sedatives

Target Protein:

Gamma-aminobutyric acid receptor subunit gamma-3

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Ociperlimab DB18947

biotech | CAS: 2342597-93-5

Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage III Unresectable Non-small Cell Lung Cancer).

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Ocrelizumab Approved DB11988

biotech | CAS: 637334-45-3

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS).[L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively…

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14

Target Protein:

B-lymphocyte antigen CD20

Waktu ParuhThe terminal elimin…

Vol. DistribusiIn a population pha…

KlirensThe constant cleara…

Genetik -

Ocriplasmin Approved DB08888

biotech | CAS: 1048016-09-6

Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Ag…

Kategori:

Amino Acids, Peptides, and ProteinsEENT Drugs, MiscellaneousEndopeptidases +10

Target Protein:

FibronectinAlpha-2-macroglobulinAlpha-2-antiplasmin

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