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1977

Total database: 17430
Struktur (SMILES)
1074 (54.3%)
Target
1046 (52.9%)
Genomik
39 (2.0%)
Referensi
1977 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (1977)

Halaman 20 / 40
JNJ-38877618 DB16883
small molecule | CAS: 943540-74-7

Deskripsi belum tersedia.

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JNJ-39220675 DB12929
small molecule | CAS: 959740-39-7

JNJ-39220675 has been used in trials studying the treatment of Allergic Rhinitis.

Kategori:
Histamine H3 Antagonists
Target Protein:
Histamine H3 receptor
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JNJ-39393406 DB11867
small molecule | CAS: 953428-73-4

JNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.

Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
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JNJ-39758979 DB18899
small molecule | CAS: 1046447-90-8

JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).

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JNJ-40346527 DB12504
small molecule | CAS: 1142363-52-7

JNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.

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JNJ-40411813 DB12059
small molecule | CAS: 1127498-03-6

JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.

Kategori:
Pyridines
Target Protein:
Metabotropic glutamate receptor 2
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JNJ-41443532 DB12632
small molecule | CAS: 1228650-83-6

JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.

Kategori:
Acids, CarbocyclicAmidesAzetines +2
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JNJ-42165279 DB15173
small molecule | CAS: 1346528-50-4

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).

Kategori:
Enzyme Inhibitors
Target Protein:
Fatty-acid amide hydrolase 1
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JNJ-42396302 DB12657
small molecule | CAS: 1298030-18-8

Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).

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JNJ-54175446 DB15358
small molecule | CAS: 1627902-21-9

JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid and Plasma).

Target Protein:
P2X purinoceptor 7
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JNJ-55308942 DB19110
small molecule | CAS: 2166558-11-6

JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

Kategori:
Neurotransmitter AgentsPurinergic AgentsPurinergic Antagonists +2
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JNJ-75276617 DB17574
small molecule

JNJ-75276617 is under investigation in clinical trial NCT05453903 (A Study of JNJ-75276617 in Combination With Acute Myeloid Leukemia (AML) Directed Therapies).

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JNT-517 DB19305
small molecule | CAS: 2837993-05-0

Deskripsi belum tersedia.

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Jojoba oil Approved DB14252
biotech | CAS: 61789-91-1

Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsCosmeticsLipids +3
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Josamycin DB01321
small molecule | CAS: 16846-24-5

A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +5
Target Protein:
50S ribosomal protein L4
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small molecule | CAS: 40922-77-8

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsLactonesMacrolides +1
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JPC-3210 DB15609
small molecule | CAS: 1609655-35-7

JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant _Plasmodium falciparum_ lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable…

Kategori:
AntimalarialsAntiviral AgentsBenzene Derivatives
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JQ1 DB17021
small molecule | CAS: 1268524-70-4

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

Target Protein:
Bromodomain-containing protein 4Bromodomain testis-specific protein
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JS-K DB17257
small molecule | CAS: 205432-12-8

Deskripsi belum tersedia.

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JSM 6427 DB06139
small molecule

JSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed. It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age…

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small molecule | CAS: 244218-93-7

An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.[A253027]

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
Nociceptin receptor
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JTK-853 DB13095
small molecule | CAS: 954389-09-4

JTK-853 has been used in trials studying the treatment of Hepatitis C Virus Infection, Response to Therapy of.

Target Protein:
Genome polyprotein
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JTT-251 DB18174
small molecule | CAS: 1627957-25-8

Deskripsi belum tersedia.

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Juglans californica pollen Approved DB10397
biotech

Juglans californica pollen is the pollen of the Juglans californica plant. Juglans californica pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juglans nigra pollen Approved DB10396
biotech

Juglans nigra pollen is the pollen of the Juglans nigra plant. Juglans nigra pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juglans regia pollen Approved DB10496
biotech

Juglans regia pollen is the pollen of the Juglans regia plant. Juglans regia pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Juniper tar Approved DB16639
biotech | CAS: 8013-10-3

Deskripsi belum tersedia.

Kategori:
Biological ProductsComplex MixturesPharmaceutical Preparations +2
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Juniperus ashei pollen Approved DB10460
biotech

Juniperus ashei pollen is the pollen of the Juniperus ashei plant. Juniperus ashei pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus californica pollen Approved DB10473
biotech

Juniperus californica pollen is the pollen of the Juniperus californica plant. Juniperus californica pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus monosperma pollen Approved DB10727
biotech

Juniperus monosperma pollen is the pollen of the Juniperus monosperma plant. Juniperus monosperma pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Juniperus occidentalis pollen is the pollen of the Juniperus occidentalis plant. Juniperus occidentalis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus osteosperma pollen Approved DB10730
biotech

Juniperus osteosperma pollen is the pollen of the Juniperus osteosperma plant. Juniperus osteosperma pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus pinchotii pollen Approved DB10728
biotech

Juniperus pinchotii pollen is the pollen of the Juniperus pinchotii plant. Juniperus pinchotii pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus scopulorum pollen Approved DB10729
biotech

Juniperus scopulorum pollen is the pollen of the Juniperus scopulorum plant. Juniperus scopulorum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus virginiana pollen Approved DB10461
biotech

Juniperus virginiana pollen is the pollen of the Juniperus virginiana plant. Juniperus virginiana pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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small molecule

JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.

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KAI-1455 DB06064
small molecule

KAI-1455 is a selective epsilon protein kinase C (?PKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting (CABG), congenital cardiac defect repair, and hip repla…

Target Protein:
Protein kinase C epsilon type
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KAI-1678 DB16211
biotech | CAS: 1041004-14-1

KAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).

Kategori:
Amino Acids, Peptides, and ProteinsProtein Kinase C-epsilon, antagonists & inhibitors
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KBP-COVID-19 DB15858
biotech

The KBP-201 COVID-19 Vaccine was developed by British American Tobacco’s (BAT) U.S. biotech subsidiary, Kentucky BioProcessing (KBP). KBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduc…

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Ketobemidone DB06738
small molecule | CAS: 469-79-4

Ketobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemi…

Kategori:
AnalgesicsCentral Nervous System AgentsCentral Nervous System Depressants +20
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor +1
Waktu ParuhPlasma half-life: 2…
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small molecule | CAS: 1297537-33-7

Ketodarolutamide, a nonsteroidal antiandrogen (NSAA), is the major active metabolite of [darolutamide].

Kategori:
AntiandrogensAntiandrogens, non-steroidal
Target Protein:
Androgen receptor
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Ketorolac Approved DB00465
small molecule | CAS: 74103-06-3

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.[L6358][L6508][L11055][L3674][L11070] It's analgesic properties make it a useful pain manage…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +26
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhKetorolac trometham…
Vol. DistribusiThe apparent volume…
KlirensThe plasma clearanc…
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Koeleria macrantha pollen Approved DB10949
biotech

Koeleria macrantha pollen is the pollen of the Koeleria macrantha plant. Koeleria macrantha pollen is mainly used in allergenic testing.

Kategori:
Allergenic ExtractsCell-mediated ImmunityGrass Pollen Allergen Extracts +3
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Kojic acid DB01759
small molecule | CAS: 501-30-4

Deskripsi belum tersedia.

Kategori:
AntioxidantsBiological FactorsCompounds used in a research, industrial, or household setting +3
Target Protein:
Tyrosinase
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Konjac mannan DB14963
small molecule | CAS: 37220-17-0

Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).

Kategori:
CarbohydratesGastrointestinal AgentsLaxatives +2
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small molecule

Deskripsi belum tersedia.

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L-Glutamine Approved DB00130
small molecule | CAS: 56-85-9

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cel…

Kategori:
Alimentary Tract and MetabolismAmino AcidsAmino Acids and Derivatives +8
Target Protein:
CTP synthase 1AmidophosphoribosyltransferaseGlutamine synthetase
Waktu ParuhThe half life of el…
Vol. DistribusiVolume of distribut…
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L523S DB06498
biotech

According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) and when delivered following incorporation into an E1B-del…

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Labetalol Approved DB00598
small molecule | CAS: 36894-69-6

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture.[L7730] Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 …

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +35
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorAlpha-1 adrenergic receptors
Waktu ParuhLabetalol has a hal…
Vol. DistribusiIn normotensive pat…
KlirensLabetalol has a pla…
Genetik -
Menampilkan 951–1000 dari 1977
Sebelumnya Halaman 20 / 40 Berikutnya