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Total database: 17430
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29 (43.3%)
Target
34 (50.7%)
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small molecule

Deskripsi belum tersedia.

Target Protein:
Transaldolase B
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Prezatide DB11296
small molecule | CAS: 49557-75-7

Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions [A19503]. Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in ch…

Kategori:
Amino Acids, Peptides, and ProteinsGrowth SubstancesPeptides
Waktu ParuhPrezatide is rapidl…
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small molecule | CAS: 89030-95-5

Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions [A19503]. Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in ch…

Kategori:
Amino Acids, Peptides, and ProteinsNuclear Matrix-Associated ProteinsNuclear Proteins +1
Waktu ParuhPrezatide is rapidl…
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Ragifilimab DB18853
biotech | CAS: 2207590-51-8

Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).

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Sabatolimab DB16322
biotech | CAS: 2252262-24-9

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +8
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Sinapultide Approved DB11332
small molecule | CAS: 138531-07-4

Sinapultide (also known as KL4 peptide) is a synthetic protein used to mimic human lung surfactant protein B.[L2502] This protein has a weight of 2469.40.[L2502] Sinapultide is a 21-residue peptide made up of lysine (K) and leucine (L) residues with the se…

Kategori:
Amino Acids, Peptides, and ProteinsPulmonary Surfactants
Target Protein:
Lung epithelial cells
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Sotigalimab DB16413
biotech | CAS: 2305607-45-6

Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
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Talquetamab Approved DB16678
biotech | CAS: 2226212-40-2

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntineoplastic Agents +7
Target Protein:
T-cell surface glycoprotein CD3G-protein coupled receptor family C group 5 member D
Waktu ParuhThe mean (CV%) term…
Vol. DistribusiThe geometric mean …
KlirensTalquetamab clearan…
Genetik -
small molecule | CAS: 1333204-77-5

Deskripsi belum tersedia.

Kategori:
Organometallic Compounds
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Terlipressin Approved DB02638
biotech | CAS: 14636-12-5

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and …

Kategori:
Amino Acids, Peptides, and ProteinsCardiovascular AgentsHormones +18
Target Protein:
Vasopressin V1a receptorVasopressin V1b receptorVasopressin V2 receptor
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of te…
Genetik -
Tranexamic acid Approved DB00302
small molecule | CAS: 1197-18-8

Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.[L31883] It was …

Kategori:
Acids, CarbocyclicAmino AcidsAmino Acids, Peptides, and Proteins +10
Target Protein:
Plasminogen
Waktu ParuhFollowing intraveno…
Vol. DistribusiThe initial volume …
KlirensThe plasma clearanc…
Genetik -
Trimethyllysine DB03977
small molecule | CAS: 19253-88-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +3
Target Protein:
Calmodulin-2Calmodulin-1Calmodulin-3 +2
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Trypsin Approved DB11237
small molecule | CAS: 9002-07-7

Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at …

Kategori:
Blood and Blood Forming OrgansDermatologicalsEndopeptidases +8
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Tuparstobart DB19118
biotech | CAS: 2649466-03-3

Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ? 1) Recurrent/metastatic Squamous Cell Carcinoma of the…

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Urokinase Approved DB00013
biotech | CAS: 9039-53-6

Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted …

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +15
Target Protein:
PlasminogenUrokinase plasminogen activator surface receptorPlasminogen activator inhibitor 1 +5
Waktu ParuhUrokinase has a hal…
Vol. DistribusiThe volume of distr…
KlirensData regarding the …
Genetik -
Xaluritamig DB18137
biotech

Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.

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small molecule | CAS: 1323976-37-9

Deskripsi belum tersedia.

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