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Total database: 17430
Struktur (SMILES)
50 (75.8%)
Target
39 (59.1%)
Genomik
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Referensi
66 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (66)

Halaman 2 / 2
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Norleucine DB15458
small molecule | CAS: 327-57-1

Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women).

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAminocaproates
Target Protein:
Hepatocyte nuclear factor 1-alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RAD 502 DB17328
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RDP58 DB06566
small molecule

RDP58 (NH2-arg-norleucine (nle)-nle-arg-nle-nle-nle-gly-tyr-CONH2) (Sangstat Corp., Fremont, California) is a novel synthetic peptide that inhibits early signal transduction pathways for the expression of inflammatory cytokines.

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +3
Waktu Paruh-
Vol. Distribusi-
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Rulonilimab DB18922
biotech | CAS: 2417124-95-7

Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).

Waktu Paruh-
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Sinapultide Approved DB11332
small molecule | CAS: 138531-07-4

Sinapultide (also known as KL4 peptide) is a synthetic protein used to mimic human lung surfactant protein B.[L2502] This protein has a weight of 2469.40.[L2502] Sinapultide is a 21-residue peptide made up of lysine (K) and leucine (L) residues with the se…

Kategori:
Amino Acids, Peptides, and ProteinsPulmonary Surfactants
Target Protein:
Lung epithelial cells
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Sirpiglenastat DB17536
small molecule | CAS: 2079939-05-0

Sirpiglenastat, also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors…

Kategori:
AcetatesAcids, AcyclicAmides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Talquetamab Approved DB16678
biotech | CAS: 2226212-40-2

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntineoplastic Agents +7
Target Protein:
T-cell surface glycoprotein CD3G-protein coupled receptor family C group 5 member D
Waktu ParuhThe mean (CV%) term…
Vol. DistribusiThe geometric mean …
KlirensTalquetamab clearan…
Genetik -
Tavaborole Approved DB09041
small molecule | CAS: 174671-46-6

Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes* infection. Tavaborole functions by inhibiting Leucyl…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +4
Target Protein:
leucine--tRNA ligase
Waktu Paruh28.5 hr
Vol. Distribusi-
Klirens-
Genetik -
Teropavimab DB18916
biotech | CAS: 2417213-72-8

Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).

Waktu Paruh-
Vol. Distribusi-
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Tobevibart DB18986
biotech | CAS: 2645440-65-7

Tobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).

Waktu Paruh-
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Tyroserleutide DB17300
small molecule | CAS: 138168-48-6

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
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Urokinase Approved DB00013
biotech | CAS: 9039-53-6

Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted …

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +15
Target Protein:
PlasminogenUrokinase plasminogen activator surface receptorPlasminogen activator inhibitor 1 +5
Waktu ParuhUrokinase has a hal…
Vol. DistribusiThe volume of distr…
KlirensData regarding the …
Genetik -
Vodudeutentan DB17410
small molecule | CAS: 2364365-83-1

Deskripsi belum tersedia.

Waktu Paruh-
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WT-1 A1 DB17352
small molecule | CAS: 852243-39-1

Deskripsi belum tersedia.

Waktu Paruh-
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