Hasil Filter

53

Total database: 17430
Struktur (SMILES)
52 (98.1%)
Target
43 (81.1%)
Genomik
3 (5.7%)
Referensi
53 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (53)

Halaman 2 / 2
Zaleplon Approved DB00962
small molecule | CAS: 151319-34-5

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug …

Kategori:
AcetatesAcids, AcyclicAmides +22
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1
Waktu ParuhApproximately 1 hour
Vol. Distribusi* 1.4 L/kg
Klirens* 1 L/h/kg
Genetik -
Zonisamide Approved DB00909
small molecule | CAS: 68291-97-4

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel…

Kategori:
Agents causing hyperkalemiaAmidesAnti-epileptic Agent +32
Target Protein:
Sodium channel protein type 1 subunit alphaSodium channel protein type 2 subunit alphaSodium channel protein type 3 subunit alpha +29
Waktu ParuhIn plasma, the elim…
Vol. DistribusiFollowing a 400 mg …
KlirensIn patients not tak…
Genetik -
Zuranolone Approved DB15490
small molecule | CAS: 1632051-40-1

Zuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABA<sub>A</sub> receptors. Unlike other more common GABA<sub>A</sub> positive allosteric modulators on the market like benzodiazepines, zuranolone can modulate both synap…

Kategori:
Antidepressive AgentsCentral Nervous System AgentsCentral Nervous System Depressants +9
Target Protein:
Gamma-aminobutyric acid receptor subunit gamma-3GABA(A) Receptor
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe volume of distr…
KlirensThe mean apparent c…
Genetik -
Menampilkan 51–53 dari 53
Sebelumnya Halaman 2 / 2 Berikutnya