Digital Pharmacy - Dashboard Peneliti

S-(Methylmercury)-L-Cysteine DB02750

small molecule

Deskripsi belum tersedia.

Target Protein:

Elongation factor-like GTPase 1

Waktu Paruh-

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S-2-(Boronoethyl)-L-Cysteine DB03731

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginase-1Arginase-2, mitochondrial

Waktu Paruh-

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S-23 DB07419

small molecule | CAS: 1010396-29-8

An androgen receptor modulator.

Kategori:

AmidesAminesAniline Compounds +2

Target Protein:

Androgen receptor

Waktu Paruh-

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S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE DB07769

small molecule

Deskripsi belum tersedia.

Target Protein:

Androgen receptor

Waktu Paruh-

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S-3304 DB12149

small molecule | CAS: 203640-27-1

S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others.

Kategori:

Enzyme InhibitorsHeterocyclic Compounds, Fused-RingMatrix Metalloproteinase Inhibitors +2

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S-3APG DB17419

small molecule

S-3APG (S-3-[3-amino-phthalimido]-glutarimide) is a derivative of thalidomide with dual activity against B-cell neoplasias.[A255168]

Kategori:

Acids, CarbocyclicHeterocyclic Compounds, Fused-RingIsoindoles +4

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S-49076 DB16821

small molecule | CAS: 1265965-22-7

Deskripsi belum tersedia.

Kategori:

Antineoplastic AgentsHeterocyclic Compounds, Fused-RingSulfur Compounds +1

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S-55746 DB18365

small molecule | CAS: 1448584-12-0

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingOxazines

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S-777469 DB16321

small molecule | CAS: 885496-53-7

S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).

Kategori:

Pyridines

Target Protein:

Cannabinoid receptor 2

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S-8510 DB06504

small molecule

S-8510 / SB-737552 is a BZD inverse agonist investigated for the treatment of Alzheimer’s disease and mild to moderate senile dementia. It was being codeveloped by Shionogi and GlaxoSmithKline.

Kategori:

BenzazepinesHeterocyclic Compounds, Fused-Ring

Target Protein:

Translocator protein

Waktu Paruh-

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S-9-(2-hydroxypropyl)adenine DB03000

small molecule | CAS: 14047-27-9

Deskripsi belum tersedia.

Target Protein:

Thymidine kinase, cytosolicThymidine kinaseAdenosine deaminase

Waktu Paruh-

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S-Adenosyl-1,8-Diamino-3-Thiooctane DB02844

small molecule | CAS: 76426-40-9

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3

Target Protein:

Polyamine aminopropyltransferase

Waktu Paruh-

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S-adenosyl-L-homocysteine DB01752

small molecule | CAS: 979-92-0

5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.

Kategori:

Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +7

Target Protein:

DNA (cytosine-5)-methyltransferase 3BHistamine N-methyltransferaseCap-specific mRNA (nucleoside-2'-O-)-methyltransferase +34

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S-Apomorphine DB16927

small molecule | CAS: 39478-62-1

Deskripsi belum tersedia.

Target Protein:

D(1A) dopamine receptorD(2) dopamine receptor

Waktu Paruh-

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S-Ethyl-N-Phenyl-Isothiourea DB03707

small molecule

Deskripsi belum tersedia.

Target Protein:

Nitric oxide synthase 1Nitric oxide synthase 3

Waktu Paruh-

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S-Hexylglutathione DB04132

small molecule | CAS: 24425-56-7

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsEnzyme InhibitorsLactoylglutathione Lyase, antagonists & inhibitors +2

Target Protein:

Hematopoietic prostaglandin D synthaseLactoylglutathione lyaseGlutathione S-transferase Mu 4 +4

Waktu Paruh-

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S-Mercaptocysteine DB02761

small molecule | CAS: 5652-32-4

Deskripsi belum tersedia.

Target Protein:

Cysteine desulfuraseThiosulfate sulfurtransferase GlpEHydroxylamine reductase +6

Waktu Paruh-

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S-Methyl glutathione DB04701

small molecule | CAS: 2922-56-7

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsOligopeptidesPeptides

Target Protein:

Glutathione S-transferase Mu 2

Waktu Paruh-

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S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE DB04720

small molecule

Deskripsi belum tersedia.

Target Protein:

Casein kinase II subunit alpha

Waktu Paruh-

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S-Methylcysteine DB02216

small molecule | CAS: 1187-84-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +4

Target Protein:

Cathepsin DMethylated-DNA--protein-cysteine methyltransferase

Waktu Paruh-

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S-Nitrosoglutathione DB17877

small molecule | CAS: 57564-91-7

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsAnti-Asthmatic AgentsAnti-Infective Agents +19

Waktu Paruh-

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S-NONYL-CYSTEINE DB07849

small molecule

Deskripsi belum tersedia.

Target Protein:

Glutathione S-transferase P

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S-palmitoyl-L-cysteine DB08342

small molecule | CAS: 114507-35-6

Deskripsi belum tersedia.

Target Protein:

Trafficking protein particle complex subunit 6ATrafficking protein particle complex subunit 3Trafficking protein particle complex subunit 6B +3

Waktu Paruh-

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S-sulphocysteine DB04370

small molecule | CAS: 1637-71-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3

Waktu Paruh-

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S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate DB08217

small molecule

Deskripsi belum tersedia.

Target Protein:

Eukaryotic translation initiation factor 4EPossible exported proteinCell adhesion molecule CEACAM5 +1

Waktu Paruh-

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S-[(2E)-3,7-DIMETHYLOCTA-2,6-DIENYL] TRIHYDROGENTHIODIPHOSPHATE DB04702

small molecule

Deskripsi belum tersedia.

Target Protein:

Prenyltransferase

Waktu Paruh-

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S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE DB07590

small molecule

Deskripsi belum tersedia.

Target Protein:

Sortase

Waktu Paruh-

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S-[5-(TRIFLUOROMETHYL)-4H-1,2,4-TRIAZOL-3-YL] 5-(PHENYLETHYNYL)FURAN-2-CARBOTHIOATE DB07743

small molecule

Deskripsi belum tersedia.

Target Protein:

Replicase polyprotein 1abReplicase polyprotein 1a

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S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE DB07602

small molecule

Deskripsi belum tersedia.

Target Protein:

Epidermal growth factor receptor

Waktu Paruh-

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S64315 DB17559

small molecule | CAS: 1799631-75-6

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).[A257311]

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S65487 DB17556

small molecule | CAS: 1644600-79-2

S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.

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Sabatolimab DB16322

biotech | CAS: 2252262-24-9

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +8

Waktu Paruh-

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Sabestomig DB19326

biotech | CAS: 2648346-74-9

Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

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Sabirnetug DB19438

biotech | CAS: 2747959-38-0

Sabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).

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Saccharin DB12418

small molecule | CAS: 81-07-2

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

Kategori:

BenzothiazolesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +9

Target Protein:

Carbonic anhydrase 1Carbonic anhydrase 9Carbonic anhydrase 12 +2

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Saccharomyces cerevisiae Approved DB10447

biotech | CAS: 68876-77-7

Saccharomyces cerevisiae is a fungus which can provoke allergic reactions. Saccharomyces cerevisiae is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +2

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Sacituzumab govitecan Approved DB12893

biotech | CAS: 1491917-83-9

Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents.[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a re…

Kategori:

AlkaloidsAmino Acids, Peptides, and ProteinsAntibodies +20

Target Protein:

Tumor-associated calcium signal transducer 2DNA topoisomerase 1Far upstream element-binding protein 1

Waktu ParuhSacituzumab govitec…

Vol. DistribusiSacituzumab govitec…

KlirensSacituzumab govitec…

Genetik -

Sacituzumab tirumotecan DB18777

biotech | CAS: 2768350-77-0

Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

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Sacrosidase Approved DB06760

biotech | CAS: 85897-35-4

Sacrosidase is a liquid enzyme preparation from S.cerevisiae used for the treatment of congenital sucrose-isomaltase deficiency (CSID). People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issues metabolizing dietary…

Kategori:

Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes +3

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Sacubitril Approved DB09292

small molecule | CAS: 149709-62-6

Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It was approved by the FDA after being given t…

Kategori:

Acids, AcyclicAgents causing angioedemaAmino Acids +13

Target Protein:

Neprilysin

Waktu ParuhThe half life of sa…

Vol. Distribusi103 L

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Genetik -

Sacubitrilat DB14127

small molecule | CAS: 149709-44-4

A metabolite of LCZ696 with neprilysin inhibitory activity.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +4

Target Protein:

Neprilysin

Waktu Paruh-

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Safflower oil Approved DB09446

biotech | CAS: 8001-23-8

Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsatura…

Kategori:

Biological ProductsComplex MixturesDiet, Food, and Nutrition +10

Waktu ParuhNo pharmacokinetic …

Vol. DistribusiNo pharmacokinetic …

KlirensNo pharmacokinetic …

Genetik -

Safinamide Approved DB06654

small molecule | CAS: 133865-89-1

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.

Kategori:

Agents that produce hypertensionAgents that reduce seizure thresholdAmines +27

Target Protein:

Amine oxidase [flavin-containing] B

Waktu Paruh22 h

Vol. Distribusi1.8 litres/kg

Klirenstotal oral clearanc…

Genetik -

Safusidenib DB18745

small molecule | CAS: 1898206-17-1

Deskripsi belum tersedia.

Waktu Paruh-

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Sage oil DB11199

biotech | CAS: 8022-56-8

Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes. *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and perennial plants with flowers. Essential oil has been t…

Kategori:

Agents that reduce seizure thresholdNon-Standardized Food Allergenic ExtractNon-Standardized Plant Allergenic Extract

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Sakuranetin DB08517

small molecule | CAS: 2957-21-3

Deskripsi belum tersedia.

Kategori:

BenzopyransBiological FactorsChromones +3

Target Protein:

Adenosine receptor A2bAdenosine receptor A1Adenosine receptor A3 +1

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Salcaprozic acid DB18517

small molecule | CAS: 183990-46-7

Deskripsi belum tersedia.

Waktu Paruh-

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Salicin DB19357

small molecule | CAS: 138-52-3

Deskripsi belum tersedia.

Kategori:

AlcoholsAnalgesicsAnalgesics, Non-Narcotic +11

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Salicylamide Approved DB08797

small molecule | CAS: 65-45-2

Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with bo…

Kategori:

Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16

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Salicylanilide Approved DB19376

small molecule | CAS: 87-17-2

Deskripsi belum tersedia.

Kategori:

AmidesAminesAnilides +2

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