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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 196 / 349
JNJ-41443532 DB12632
small molecule | CAS: 1228650-83-6

JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.

Kategori:
Acids, CarbocyclicAmidesAzetines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JNJ-42165279 DB15173
small molecule | CAS: 1346528-50-4

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).

Kategori:
Enzyme Inhibitors
Target Protein:
Fatty-acid amide hydrolase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JNJ-42396302 DB12657
small molecule | CAS: 1298030-18-8

Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).

Waktu Paruh-
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JNJ-54175446 DB15358
small molecule | CAS: 1627902-21-9

JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid and Plasma).

Target Protein:
P2X purinoceptor 7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JNJ-55308942 DB19110
small molecule | CAS: 2166558-11-6

JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

Kategori:
Neurotransmitter AgentsPurinergic AgentsPurinergic Antagonists +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JNJ-75276617 DB17574
small molecule

JNJ-75276617 is under investigation in clinical trial NCT05453903 (A Study of JNJ-75276617 in Combination With Acute Myeloid Leukemia (AML) Directed Therapies).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JNT-517 DB19305
small molecule | CAS: 2837993-05-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Jojoba oil Approved DB14252
biotech | CAS: 61789-91-1

Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsCosmeticsLipids +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Josamycin DB01321
small molecule | CAS: 16846-24-5

A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +5
Target Protein:
50S ribosomal protein L4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 40922-77-8

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsLactonesMacrolides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JPC-3210 DB15609
small molecule | CAS: 1609655-35-7

JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant _Plasmodium falciparum_ lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable…

Kategori:
AntimalarialsAntiviral AgentsBenzene Derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JQ1 DB17021
small molecule | CAS: 1268524-70-4

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

Target Protein:
Bromodomain-containing protein 4Bromodomain testis-specific protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
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JS-K DB17257
small molecule | CAS: 205432-12-8

Deskripsi belum tersedia.

Waktu Paruh-
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JSM 6427 DB06139
small molecule

JSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed. It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age…

Waktu Paruh-
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Genetik -
small molecule | CAS: 244218-93-7

An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.[A253027]

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
Nociceptin receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JTK-853 DB13095
small molecule | CAS: 954389-09-4

JTK-853 has been used in trials studying the treatment of Hepatitis C Virus Infection, Response to Therapy of.

Target Protein:
Genome polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
JTT-251 DB18174
small molecule | CAS: 1627957-25-8

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Juglans californica pollen Approved DB10397
biotech

Juglans californica pollen is the pollen of the Juglans californica plant. Juglans californica pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Juglans nigra pollen Approved DB10396
biotech

Juglans nigra pollen is the pollen of the Juglans nigra plant. Juglans nigra pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Juglans regia pollen Approved DB10496
biotech

Juglans regia pollen is the pollen of the Juglans regia plant. Juglans regia pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
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Juniper tar Approved DB16639
biotech | CAS: 8013-10-3

Deskripsi belum tersedia.

Kategori:
Biological ProductsComplex MixturesPharmaceutical Preparations +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Juniperus ashei pollen Approved DB10460
biotech

Juniperus ashei pollen is the pollen of the Juniperus ashei plant. Juniperus ashei pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Juniperus californica pollen Approved DB10473
biotech

Juniperus californica pollen is the pollen of the Juniperus californica plant. Juniperus californica pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Juniperus monosperma pollen Approved DB10727
biotech

Juniperus monosperma pollen is the pollen of the Juniperus monosperma plant. Juniperus monosperma pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Juniperus occidentalis pollen is the pollen of the Juniperus occidentalis plant. Juniperus occidentalis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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Genetik -
Juniperus osteosperma pollen Approved DB10730
biotech

Juniperus osteosperma pollen is the pollen of the Juniperus osteosperma plant. Juniperus osteosperma pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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Genetik -
Juniperus pinchotii pollen Approved DB10728
biotech

Juniperus pinchotii pollen is the pollen of the Juniperus pinchotii plant. Juniperus pinchotii pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Juniperus scopulorum pollen Approved DB10729
biotech

Juniperus scopulorum pollen is the pollen of the Juniperus scopulorum plant. Juniperus scopulorum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Juniperus virginiana pollen Approved DB10461
biotech

Juniperus virginiana pollen is the pollen of the Juniperus virginiana plant. Juniperus virginiana pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.

Waktu Paruh-
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K-00546 DB07664
small molecule | CAS: 443798-47-8

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 1Cyclin-dependent kinase 1Cyclin-dependent kinase 2 +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
K-134 DB12685
small molecule | CAS: 189362-06-9

K-134 has been used in trials studying the treatment of Intermittent Claudication.

Kategori:
AmidesHeterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
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Genetik -
K-252a DB02152
small molecule | CAS: 97161-97-2

Deskripsi belum tersedia.

Kategori:
AlkaloidsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Dual specificity mitogen-activated protein kinase kinase 1Hepatocyte growth factor receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
K-777 DB17760
small molecule | CAS: 502960-90-9

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +5
Target Protein:
Cruzipain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
K201 free base DB02929
small molecule | CAS: 145903-06-6

Deskripsi belum tersedia.

Target Protein:
Annexin A5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
KAb201 DB17210
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Kabiramide C DB03616
small molecule

Deskripsi belum tersedia.

Target Protein:
Actin, alpha skeletal muscle
Waktu Paruh-
Vol. Distribusi-
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Kaempferia galanga root Approved DB14288
biotech

Kaempferia galanga root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
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Kaempherol DB01852
small molecule | CAS: 520-18-3

Deskripsi belum tersedia.

Target Protein:
Polyunsaturated fatty acid 5-lipoxygenasePolyunsaturated fatty acid lipoxygenase ALOX15Aldo-keto reductase family 1 member B1 +5
Waktu Paruh-
Vol. Distribusi-
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Genetik -
KAHR-102 DB17427
biotech

KAHR-102 is a dual signaling protein fusing cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) to the Fas-ligand (FasL).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
KAI-1455 DB06064
small molecule

KAI-1455 is a selective epsilon protein kinase C (?PKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting (CABG), congenital cardiac defect repair, and hip repla…

Target Protein:
Protein kinase C epsilon type
Waktu Paruh-
Vol. Distribusi-
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Genetik -
KAI-1678 DB16211
biotech | CAS: 1041004-14-1

KAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).

Kategori:
Amino Acids, Peptides, and ProteinsProtein Kinase C-epsilon, antagonists & inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Kale DB14564
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Kallidinogenase DB13197
biotech | CAS: 9001-01-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Kanamycin Approved DB01172
small molecule | CAS: 59-01-8

Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus a…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAminoglycoside Antibacterials +16
Target Protein:
30S ribosomal protein S1216S ribosomal RNA
Waktu Paruh2.5 hours
Vol. Distribusi-
Klirens-
Genetik -
KAND567 DB16511
small molecule | CAS: 911715-90-7

KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation[L32908]. Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as a treatment for…

Kategori:
Experimental Unapproved Treatments for COVID-19
Target Protein:
CX3C chemokine receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Kaolin Approved DB01575
small molecule | CAS: 1332-58-7

Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance o…

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Silicates +11
Waktu Paruh-
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Kappadione Approved DB09332
small molecule | CAS: 131-13-5

Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America [L1543]. It has been found…

Target Protein:
ProthrombinCoagulation factor VIICoagulation factor IX +4
Waktu ParuhMean elimination ha…
Vol. DistribusiIn a study of rabbi…
KlirensThe plasma clearanc…
Genetik -
Karaya gum Approved DB10535
biotech | CAS: 9000-36-6

Karaya gum allergenic extract is used in allergenic testing.

Kategori:
Alimentary Tract and MetabolismBiological ProductsBiopolymers +19
Waktu Paruh-
Vol. Distribusi-
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Genetik -
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