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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 194 / 272
NYX-2925 DB19149
small molecule | CAS: 2012536-16-0

NYX-2925 is under investigation in clinical trial NCT04146896 (Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
4-hydroxy-tetrahydrodipicolinate synthase
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
Poly [ADP-ribose] polymerase 1Exotoxin AElongation factor 2 +3
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small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin S
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small molecule

Deskripsi belum tersedia.

Target Protein:
Serine/threonine-protein kinase/endoribonuclease IRE1
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small molecule

Deskripsi belum tersedia.

Target Protein:
N-succinylarginine dihydrolase
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Mitogen-activated protein kinase 14
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carboxypeptidase A1
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Genetik -
small molecule | CAS: 67262-86-6

Deskripsi belum tersedia.

Kategori:
AntigensAntigens, NeoplasmBiological Factors +3
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small molecule | CAS: 5147-00-2

Deskripsi belum tersedia.

Target Protein:
Prostaglandin G/H synthase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Capsid scaffolding proteinSubtilisin SavinaseTrypsin-2 +2
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o-Cymen-5-ol DB15901
small molecule | CAS: 3228-02-2

Deskripsi belum tersedia.

Kategori:
Benzene Derivatives
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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small molecule

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Mannose-binding protein C
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Obatoclax DB12191
small molecule | CAS: 803712-67-6

Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring
Target Protein:
Apoptosis regulator Bcl-2Induced myeloid leukemia cell differentiation protein Mcl-1Bcl-2-like protein 1
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OBE101 DB05080
small molecule

OBE101 is a new weight loss drug developed by Obecure Ltd. It is a new formulation that is based on the vertigo medication, Betahistine. Obecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment o…

Target Protein:
Histamine H1 receptorHistamine H3 receptor
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Obecabtagene autoleucel Approved DB17362
biotech

Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.

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Obeldesivir DB18821
small molecule | CAS: 2647441-36-7

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
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Obeticholic acid Approved DB05990
small molecule | CAS: 459789-99-2

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.[A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to…

Kategori:
Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +14
Target Protein:
Bile acid receptor
Waktu ParuhThe biological half…
Vol. DistribusiThe volume of distr…
KlirensClearance informati…
Genetik -
Obexelimab DB15032
biotech | CAS: 1690307-05-1

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

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OBI-3424 DB16057
small molecule | CAS: 2097713-68-1

OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL)).

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OBI-833 DB19270
biotech | CAS: 2142641-90-3

Deskripsi belum tersedia.

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OBI-999 DB17356
biotech

Deskripsi belum tersedia.

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Obicetrapib DB14890
small molecule | CAS: 866399-87-3

Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Cholesteryl ester transfer protein
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Obidoxime DB13750
small molecule | CAS: 7683-36-5

Deskripsi belum tersedia.

Kategori:
AminesAntidotesCholinergic Agents +7
Target Protein:
Acetylcholinesterase
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Obiltoxaximab Approved DB05336
biotech | CAS: 1351337-07-9

Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis to…

Kategori:
Amino Acids, Peptides, and ProteinsAnthrax Protective Antigen-directed AntibodyAnthrax Protective Antigen-directed Antibody Interactions +15
Target Protein:
Protective antigen
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Obinepitide DB05045
small molecule | CAS: 348119-84-6

Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from t…

Target Protein:
Neuropeptide Y receptor type 4Neuropeptide Y receptor type 2
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Obinutuzumab Approved DB08935
biotech | CAS: 949142-50-1

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +20
Target Protein:
B-lymphocyte antigen CD20
Waktu ParuhThe half life of ob…
Vol. DistribusiObinutuzumab has a …
KlirensThe clearance of ob…
Genetik -
Oblimersen DB13811
small molecule | CAS: 190977-41-4

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsAntisense Elements (Genetics) +13
Target Protein:
Apoptosis regulator Bcl-2
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OBP-801 DB12279
small molecule | CAS: 328548-11-4

OBP-801 has been used in trials studying the treatment of Solid Tumor.

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsHistone Deacetylase Inhibitors +2
Target Protein:
Histone deacetylase 1
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OC-1012 DB05834
small molecule

OC-1012 is a compound which has emerged as a promising therapeutic agent for the treatment and prevention of mucositis, a serious side effect of chemotherapy and head and neck radiation therapy.

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OC-459 DB11900
small molecule | CAS: 851723-84-7

OC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Target Protein:
Prostaglandin D2 receptor 2
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Ocaperidone DB06229
small molecule | CAS: 129029-23-8

Deskripsi belum tersedia.

Kategori:
Pyrimidines
Target Protein:
5-hydroxytryptamine receptor 2AD(2) dopamine receptorHistamine H1 receptor +8
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Ocaratuzumab DB17359
biotech | CAS: 1169956-08-4

Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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Ochromycinone DB15644
small molecule | CAS: 28882-53-3

Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).

Kategori:
AnthracenesQuinones
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Ocifisertib DB18746
small molecule | CAS: 1338806-73-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyrazoles
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Ocimum tenuiflorum top Approved DB14273
biotech

Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Ociperlimab DB18947
biotech | CAS: 2342597-93-5

Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage III Unresectable Non-small Cell Lung Cancer).

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Ocrelizumab Approved DB11988
biotech | CAS: 637334-45-3

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS).[L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14
Target Protein:
B-lymphocyte antigen CD20
Waktu ParuhThe terminal elimin…
Vol. DistribusiIn a population pha…
KlirensThe constant cleara…
Genetik -
Ocrylate DB15086
small molecule | CAS: 6701-17-3

Ocrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).

Kategori:
Acids, AcyclicAcrylatesCompounds used in a research, industrial, or household setting +7
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