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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Hasil Pencarian (15718)

Halaman 189 / 315
small molecule | CAS: 28184-71-6

Deskripsi belum tersedia.

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Magnesium carbonate Approved DB09481
small molecule | CAS: 546-93-0

Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +20
Target Protein:
Glutamate (NMDA) receptor
Waktu ParuhHalf life of 27.7 h…
Vol. DistribusiVd for magnesium is…
KlirensMaximum magnesium c…
Genetik -
Magnesium cation Approved DB01378
small molecule | CAS: 22537-22-0

Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestio…

Kategori:
Agents that produce neuromuscular block (indirect)Calculi Dissolution AgentIncreased Large Intestinal Motility +9
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu Paruh-
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Magnesium citrate Approved DB11110
small molecule | CAS: 3344-18-1

Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used.[T215] Magnesium citrate is considered by the FDA as an…

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +15
Waktu ParuhThe study of the ha…
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Magnesium gluconate Approved DB13749
small molecule | CAS: 59625-89-7

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to …

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +7
Waktu Paruh-
Vol. DistribusiAbout 60% of the ma…
KlirensThe kidney plays a …
Genetik -
Magnesium glycinate Approved DB11189
small molecule | CAS: 14783-68-7

Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source of magnesium. It is used in the treatment of magnesium deficiency.

Kategori:
Agents that produce neuromuscular block (indirect)Laxatives
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Magnesium hydroxide Approved DB09104
small molecule | CAS: 1309-42-8

Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke …

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAlkalies +22
Waktu ParuhN/A
Vol. DistribusiThe peak action and…
KlirensMagnesium hydroxide…
Genetik -
small molecule | CAS: 18917-93-6

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismMagnesium CompoundsMetal cations +2
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu Paruh-
Vol. Distribusi-
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small molecule | CAS: 58505-81-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismEnzyme InhibitorsKeto Acids +4
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu Paruh-
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Magnesium malate Approved DB15555
small molecule | CAS: 869-06-7

Deskripsi belum tersedia.

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small molecule | CAS: 83918-60-9

Deskripsi belum tersedia.

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small molecule | CAS: 34717-03-8

Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhib…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismMagnesium Compounds +5
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Magnesium oxide Approved DB01377
small molecule | CAS: 1309-48-4

Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +16
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small molecule | CAS: 14452-57-4

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAluminum and magnesium containing antacidsAnions +15
Waktu Paruh-
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Genetik -
small molecule | CAS: 7757-87-1

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAgents that produce neuromuscular block (indirect) +10
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small molecule | CAS: 18917-89-0

Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of th…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +23
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
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Magnesium silicate Approved DB13249
small molecule | CAS: 1343-88-0

Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O.[T186] It is known as talc and it presents …

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAluminum and magnesium containing antacids +9
Waktu ParuhThe very low absorp…
Vol. DistribusiThe very low absorp…
KlirensThe very low absorp…
Genetik -
small molecule | CAS: 557-04-0

Deskripsi belum tersedia.

Kategori:
Agents that produce neuromuscular block (indirect)Fatty AcidsLipids
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Magnesium sulfate Approved DB00653
small molecule | CAS: 7487-88-9

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncou…

Kategori:
Agents causing hyperkalemiaAgents that produce neuromuscular block (indirect)Alimentary Tract and Metabolism +38
Target Protein:
Voltage-dependent L-type calcium channel
Waktu Paruh43.2 hours (for new…
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Magnesium trisilicate Approved DB09281
small molecule | CAS: 14987-04-3

Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.

Kategori:
Agents that produce neuromuscular block (indirect)Aluminum and magnesium containing antacidsAntacids +10
Waktu Paruh16-20 hours
Vol. DistribusiThe hydrated silico…
KlirensMaximum magnesium c…
Genetik -
biotech

Deskripsi belum tersedia.

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biotech

Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Magrolimab DB16225
biotech | CAS: 2169232-81-7

Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
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MAHDL01 DB06270
small molecule

MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.

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MAK-683 DB19205
small molecule | CAS: 1951408-58-4

Deskripsi belum tersedia.

Target Protein:
Polycomb protein EED
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Malachite Green DB03895
small molecule | CAS: 10309-95-2

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAminesAniline Compounds +7
Target Protein:
HTH-type transcriptional regulator QacR
Waktu Paruh-
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Malacidin A DB14051
biotech

Malacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. Wh…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAnti-Infective Agents +3
Target Protein:
NAM/NAG peptide subunits of peptidoglycan
Waktu Paruh-
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Malacidin B DB14052
small molecule

Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. Wh…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAnti-Infective Agents +3
Target Protein:
NAM/NAG peptide subunits of peptidoglycan
Waktu Paruh-
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Malathion Approved DB00772
small molecule | CAS: 121-75-5

Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.

Kategori:
AgrochemicalsAntiparasitic Products, Insecticides and RepellentsCholinergic Agents +19
Target Protein:
CholinesteraseAcetylcholinesterase
Waktu Paruh8-24 hours
Vol. Distribusi-
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Maleic acid DB04299
small molecule | CAS: 110-16-7

Deskripsi belum tersedia.

Kategori:
Acid Etching, DentalAcids, AcyclicDicarboxylic Acids +1
Target Protein:
Aspartate aminotransferaseTrypanothione reductaseAspartate aminotransferase +2
Waktu Paruh-
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Malic acid DB12751
small molecule | CAS: 6915-15-7

Malic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension.

Kategori:
Acids, AcyclicDicarboxylic AcidsHydroxy Acids
Waktu Paruh-
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Malonate Ion DB02201
small molecule

Deskripsi belum tersedia.

Target Protein:
Chorismate mutase AroHStromal cell-derived factor 2
Waktu Paruh-
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Malonic acid DB02175
small molecule | CAS: 141-82-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDicarboxylic AcidsThallium
Target Protein:
Aspartate 1-decarboxylaseProto-oncogene tyrosine-protein kinase SrcSigma factor SigB regulation protein RsbQ +4
Waktu Paruh-
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Malonyl-CoA DB04524
small molecule | CAS: 524-14-1

A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
3-oxoacyl-[acyl-carrier-protein] synthase 3
Waktu Paruh-
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MALP-2 DB18482
small molecule | CAS: 250718-44-6

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsLipidsMacrophage Activation +1
Waktu Paruh-
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Malpighia emarginata extract Approved DB16545
biotech

Deskripsi belum tersedia.

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Maltitol DB16867
small molecule | CAS: 585-88-6

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesDisaccharides +4
Waktu Paruh-
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Maltodextrin DB12583
small molecule | CAS: 9050-36-6

Deskripsi belum tersedia.

Kategori:
Carbohydrates
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
Pancreatic alpha-amylase
Waktu Paruh-
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Maltotetraose DB02237
small molecule | CAS: 34612-38-9

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsCarbohydrates +5
Target Protein:
Glucan 1,4-alpha-maltotetraohydrolaseNeopullulanase 2
Waktu Paruh-
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small molecule | CAS: 280782-97-0

CS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsFructose-Bisphosphatase, antagonists & inhibitors +1
Target Protein:
Fructose-1,6-bisphosphatase 1
Waktu Paruh-
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Mandelic acid Approved DB13218
small molecule | CAS: 90-64-2

Mandelic acid is an approved aromatic, alpha hydroxy acid [L5458]. Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.

Kategori:
Acids, CarbocyclicAnti-Infective AgentsAntibacterials for Systemic Use +5
Waktu Paruh-
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MANF DB17885
biotech

MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor.

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Mangafodipir Approved DB06796
small molecule | CAS: 155319-91-8

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent…

Kategori:
AcetatesAcids, AcyclicAmines +15
Waktu ParuhThe mean initial pl…
Vol. DistribusiThe volume of distr…
KlirensThe approximate tot…
Genetik -
Manganese cation Approved DB06757
small molecule | CAS: 16397-91-4

Manganese is a transition metal that was first described in the 19th and 20th centuries.[A263657] It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake p…

Kategori:
Diet, Food, and NutritionElectrolytesElements +12
Target Protein:
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIsocitrate dehydrogenase [NAD] subunit gamma, mitochondrialTGF-beta-activated kinase 1 and MAP3K7-binding protein 1 +5
Waktu Paruh-
Vol. DistribusiMn can cross the bl…
Klirens-
Genetik -
Manganese citrate Approved DB14495
small molecule | CAS: 10060-26-1

Deskripsi belum tersedia.

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Manganese gluconate Approved DB11141
small molecule | CAS: 6485-39-8

Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink pow…

Kategori:
Acids, AcyclicCarbohydratesHydroxy Acids +1
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Mangifera indica pollen Approved DB10733
biotech

Mangifera indica pollen is the pollen of the Mangifera indica plant. Mangifera indica pollen is mainly used in allergenic testing.

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Mango Approved DB10657
biotech

Mango allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Mangostin DB14371
biotech | CAS: 6147-11-1

Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Heterocyclic Compounds, Fused-RingProtein Kinase InhibitorsXanthenes
Target Protein:
Polyunsaturated fatty acid lipoxygenase ALOX15
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