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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Halaman 188 / 315
LY3884961 DB17070
biotech

LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.[L43468]

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Lycopene Approved DB11231
small molecule | CAS: 502-65-8

Lycopene is a naturally occurring red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and other foods [A27242]. Having a chemical formula of C40H56, lycopene is a tetraterpene assembled from eight isoprene unit…

Kategori:
AlkenesAnti-Inflammatory AgentsAnticarcinogenic Agents +13
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Lym-1-I-131 DB17445
biotech

Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.

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Lymecycline Approved DB00256
small molecule | CAS: 992-21-2

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with comparable…

Kategori:
Agents that produce neuromuscular block (indirect)Anti-Bacterial AgentsAnti-Infective Agents +4
Target Protein:
30S ribosomal protein S4
Waktu ParuhThe half-life of ly…
Vol. DistribusiLymecycline is lipo…
KlirensLymecycline is part…
Genetik -
Lynestrenol Approved DB12474
small molecule | CAS: 52-76-6

Lynestrenol is a progestin and prodrug of [norethisterone].

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +25
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biotech

Deskripsi belum tersedia.

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Lypressin Approved DB14642
small molecule | CAS: 50-57-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntidiuretic AgentsCardiovascular Agents +20
Target Protein:
Vasopressin V1a receptorVasopressin V2 receptorVasopressin V1b receptor
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small molecule

Lysergic acid 2,4-dimethylazetidide is under investigation in clinical trial NCT02765802 (A Study to Evaluate Pegylated Interferon Lambda Monotherapy in Patients With Chronic Hepatitis Delta Virus Infection).

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Lysine Approved DB00123
small molecule | CAS: 56-87-1

Lysine (abbreviated as Lys or K) is an ?-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and his…

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +10
Target Protein:
High affinity cationic amino acid transporter 1Cationic amino acid transporter 4Cationic amino acid transporter 3 +2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Cyclin-dependent kinase 2Beta-lactamase OXA-10UDP-N-acetylmuramoylalanine--D-glutamate ligase +16
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small molecule

Deskripsi belum tersedia.

Target Protein:
Prothrombin
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Lysozyme DB13260
biotech | CAS: 12650-88-3

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseDermatologicals +6
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LYT-200 DB18179
biotech

LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.

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small molecule | CAS: 156021-12-4

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acetylcholinesterase
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M-032 DB17258
biotech

Deskripsi belum tersedia.

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M-2698 DB15431
small molecule | CAS: 1379545-95-5

M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).

Target Protein:
RAC-alpha serine/threonine-protein kinaseRAC-gamma serine/threonine-protein kinaseRibosomal protein S6 kinase beta-1
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M-701 DB17504
biotech

M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-lactamaseBeta-lactamase
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small molecule | CAS: 6640-24-0

m-Chlorophenylpiperazine has been used in trials studying the treatment of Alcoholism.

Kategori:
Antidepressive AgentsCentral Nervous System DepressantsNeurotransmitter Agents +7
Target Protein:
5-hydroxytryptamine receptor 1E5-hydroxytryptamine receptor 75-hydroxytryptamine receptor 6 +4
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M-Cresol DB01776
small molecule | CAS: 108-39-4

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesPhenols
Target Protein:
Insulin
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small molecule | CAS: 1637-75-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +3
Target Protein:
Kynureninase
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M0002 DB05091
small molecule

M0002 is an orally-active selective vasopressin antagonist that inhibits water re-absorption from the kidneys. It is a vasopressin 2 antagonist and represents a new class of compounds – aquaretics – that produce profound diuresis without loss of electrolytes.…

Target Protein:
Vasopressin V2 receptor
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M002 DB18318
biotech

Deskripsi belum tersedia.

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Genetik -
M012 DB18243
biotech

Deskripsi belum tersedia.

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M1-c6v1 DB18596
biotech

M1-c6v1 is a recombinant oncolytic virus.

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MaaT013 DB18648
biotech

MaaT013 is an allogeneic fecal microbiota therapy. It is being investigated for the treatment of Graft-Versus-Host Disease.

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Macadamia nut Approved DB10655
biotech

Macadamia nut allergenic extract is used in allergenic testing.

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Macadamia oil DB14330
biotech

Macadamia oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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biotech

Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Macelignan DB14129
small molecule | CAS: 107534-93-0

Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.

Kategori:
Benzene DerivativesBenzyl Compounds
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Macimorelin Approved DB13074
small molecule | CAS: 381231-18-1

Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis of adult GH deficiency (AGHD). More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH sec…

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +11
Target Protein:
Growth hormone secretagogue receptor type 1
Waktu ParuhThe mean terminal h…
Vol. DistribusiFollowing a single …
KlirensFollowing a single …
Genetik -
Macitentan Approved DB08932
small molecule | CAS: 441798-33-0

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. Macitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotox…

Kategori:
AmidesAntihypertensive AgentsAntihypertensives for Pulmonary Arterial Hypertension +13
Target Protein:
Endothelin-1 receptorEndothelin receptor type B
Waktu ParuhThe half-life of el…
Vol. DistribusiMacitentan has an a…
KlirensClearance data was …
Genetik -
Mackerel Approved DB10618
biotech

Mackerel allergenic extract is used in allergenic testing.

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Maclura pomifera pollen Approved DB10988
biotech

Maclura pomifera pollen is the pollen of the Maclura pomifera plant. Maclura pomifera pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Maclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Macozinone DB14821
small molecule | CAS: 1377239-83-2

Macozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsDrugs for Treatment of Tuberculosis +1
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Madecassic acid DB14037
small molecule | CAS: 18449-41-7

Deskripsi belum tersedia.

Kategori:
Terpenes
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Madecassoside DB15532
small molecule | CAS: 34540-22-2

Deskripsi belum tersedia.

Kategori:
Terpenes
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Maduramicin DB11525
small molecule | CAS: 84878-61-5

Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsIonophores
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Mafenide Approved DB06795
small molecule | CAS: 138-39-6

Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.[L36773] In 1998, mafenide acetate was approved under the FDA’s accelerat…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +14
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 12Carbonic anhydrase 14 +2
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Mafosfamide DB12083
small molecule | CAS: 88859-04-5

Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.

Kategori:
Adjuvants, ImmunologicAntineoplastic AgentsHydrocarbons, Halogenated +6
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Maftivimab Approved DB15899
biotech | CAS: 2135632-36-7

Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%.[A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming …

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntibodies +10
Target Protein:
Envelope glycoprotein
Waktu ParuhMaftivimab administ…
Vol. DistribusiMaftivimab administ…
KlirensMaftivimab administ…
Genetik -
Magaldrate Approved DB08938
small molecule | CAS: 74978-16-8

Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.

Kategori:
Alimentary Tract and MetabolismAlkaliesAluminium Compounds +13
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Magnesium Approved DB14513
small molecule | CAS: 7439-95-4

Magnesium is classified as an alkaline earth metal and has 2 hydration shells.[A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate.[A19349] Common dietary sources of magnesium incl…

Kategori:
ElementsLaxativesMagnesium Compounds +6
Waktu ParuhMagnesiums biologic…
Vol. DistribusiAccording to a phar…
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Magnesium acetate Approved DB13996
small molecule | CAS: 142-72-3

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAgents that produce neuromuscular block (indirect)Fatty Acids +3
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
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small molecule | CAS: 16674-78-5

Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble …

Kategori:
Agents that produce neuromuscular block (indirect)Laxatives
Target Protein:
Glutamate (NMDA) receptor
Waktu ParuhElimination half-li…
Vol. DistribusiMagnesium ions disp…
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Magnesium Aluminum Silicate Approved DB11230
small molecule | CAS: 1327-43-1

Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group [A32782]. It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, …

Kategori:
Agents that produce neuromuscular block (indirect)MineralsPharmaceutic Aids +1
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Magnesium ascorbate Approved DB14484
small molecule | CAS: 15431-40-0

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAntioxidantsBiological Factors +10
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small molecule | CAS: 7018-07-7

Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium o…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAmino Acids +8
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