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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 185 / 282
MRT5201 DB17656
biotech

Deskripsi belum tersedia.

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MRTX-1719 DB18016
small molecule | CAS: 2630904-44-6

Deskripsi belum tersedia.

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MRX-I DB12796
small molecule | CAS: 1112968-42-9

MRX-I has been used in trials studying the treatment of Bacterial Infections.

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MRx0518 DB17523
biotech

Deskripsi belum tersedia.

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MSX-122 DB12715
small molecule | CAS: 897657-95-3

MSX-122 has been used in trials studying the treatment of Solid Tumors.

Kategori:
Receptors, CXCR4, antagonists & inhibitors
Target Protein:
C-X-C chemokine receptor type 4
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MT1621 DB17970
small molecule

Deskripsi belum tersedia.

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MTI-201 DB17169
biotech

Deskripsi belum tersedia.

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Mubritinib DB12682
small molecule | CAS: 366017-09-6

Mubritinib has been used in trials studying the treatment of Lung Neoplasm, Renal Neoplasm, Breast Neoplasm, Ovarian Neoplasm, and Pancreatic Neoplasm.

Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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biotech

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Mucuna pruriens seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Mufemilast DB18075
small molecule | CAS: 1255909-03-5

Deskripsi belum tersedia.

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MultiStem DB15742
biotech

MultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs). Like mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hematopoietically adherent. …

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Muparfostat DB05808
small molecule | CAS: 1020105-89-8

Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.

Kategori:
CarbohydratesPolysaccharides
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Mupirocin Approved DB00410
small molecule | CAS: 12650-69-0

Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism _Pseudomonas fluorescens_, mupirocin is …

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibiotics for Topical Use +12
Target Protein:
Isoleucine--tRNA ligase
Waktu ParuhIn healthy male vol…
Vol. DistribusiNo information avai…
KlirensNo information avai…
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Muplestim DB12431
biotech | CAS: 148641-02-5

Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCarbohydrates +10
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Muraglitazar DB06510
small molecule | CAS: 331741-94-7

Muraglitazar (Bristol-Myers Squibb/Merck) is a new agent under investigation for the treatment of patients with type 2 diabetes. It belongs to a novel class of drugs that target the peroxisome proliferator-activated receptors, both alpha and gamma subtypes. I…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsCytochrome P-450 CYP1A2 Substrates +6
Target Protein:
Peroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alpha
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Mureletecan DB15020
small molecule | CAS: 246527-99-1

Mureletecan is under investigation in clinical trial NCT00004076 (PNU 166148 in Treating Patients With Metastatic Solid Tumors).

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Murepavadin DB14777
small molecule | CAS: 944252-63-5

Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAnti-Infective Agents +1
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Murizatoclax DB17977
small molecule | CAS: 2245848-05-7

Deskripsi belum tersedia.

Target Protein:
Induced myeloid leukemia cell differentiation protein Mcl-1
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Murlentamab DB17214
biotech | CAS: 2058047-65-5

Deskripsi belum tersedia.

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Muromonab Approved DB00075
biotech | CAS: 140608-64-6

Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine asci…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +17
Target Protein:
T-cell surface glycoprotein CD3 delta chainT-cell surface glycoprotein CD3 epsilon chainT-cell surface glycoprotein CD3 gamma chain +2
Waktu Paruh0.8 hours (mammalia…
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Mus musculus skin Approved DB10412
biotech

Mus musculus skin or pelt is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Muscimol DB12458
small molecule | CAS: 2763-96-4

Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.

Kategori:
Biological FactorsGABA AgentsGABA Agonists +5
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit beta-3Gamma-aminobutyric acid receptor subunit gamma-2
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Muzolimine Approved DB13801
small molecule | CAS: 55294-15-0

Deskripsi belum tersedia.

Kategori:
Antihypertensive AgentsCardiovascular AgentsDiuretics +4
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MV-NB-02 DB17305
biotech

Deskripsi belum tersedia.

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biotech

MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury…

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MVA-BN-HER-2 DB05733
small molecule

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MVA-mBN226B DB17780
biotech

Deskripsi belum tersedia.

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MVA-SARS-2-S DB16432
biotech

MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein[L30453]. MVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to its…

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MVC-COV1901 DB15854
biotech

MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. Medigen has combined forces with Dynavax, which offers an adv…

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MVR-T3011 DB17378
biotech

MVR-T3011 is a genetically modified oncolytic Herpes Simplex Virus (HSV-1) with 2 exogenous genes encoding the active heterodimer human interleukin 12 (IL-12) and the Fab fragment of an anti-human PD-1 antibody.

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MW33 DB16358
biotech

MW33 is a recombinant fully human antibody to SARS-CoV-2.[L27411] This antibody injection is currently being investigated against COVID-19 in the clinical trial NCT04533048 (A Clinical Study to Evaluate MW33 Injection).

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MX6 DB05789
small molecule

MX6 is adamantyl group derivatives containing retinoid-related compounds induce apoptosis of cancer cells and therefore may be used for the treatment of cancer, including advanced cancer. More specifically, it has been shown that such adamantyl compounds, e.g…

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biotech

The Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. As an immunotherapy, M.w is used against leprosy; the compound also shares antigens with M. tuberculosis. Its use has show…

Kategori:
Biological ProductsComplex MixturesMycobacterium +1
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Mycophenolate mofetil Approved DB00688
small molecule | CAS: 128794-94-5

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH).[A180805] This drug is an immunosuppressant combined with drugs such as [Cyclospor…

Kategori:
Agents Causing Muscle ToxicityAnti-Bacterial AgentsAnti-Infective Agents +23
Target Protein:
Prostaglandin E2 receptor EP2 subtypeInosine-5'-monophosphate dehydrogenase 1Inosine-5'-monophosphate dehydrogenase 2 +1
Waktu ParuhThe average apparen…
Vol. DistribusiThe volume of distr…
KlirensPlasma clearance of…
Genetik -
Mycophenolic acid Approved DB01024
small molecule | CAS: 24280-93-1

Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.[L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.[A249170]. Mycophenolic acid is us…

Kategori:
Acids, AcyclicAnti-Bacterial AgentsAnti-Infective Agents +27
Target Protein:
Inosine-5'-monophosphate dehydrogenase 2Inosine-5'-monophosphate dehydrogenase 1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiAt steady state, th…
KlirensThe mean clearance …
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsMembrane ProteinsMyelin Basic Protein +3
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MYR-101 DB17075
biotech

MYR-101 (rAAV-Olig001-ASPA) is a recombinant adeno-associated virus (rAAV) vector-based gene therapy intended to treat Canavan disease. Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain. It is caused…

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Myrcludex B DB14853
biotech | CAS: 406461-66-3

Myrcludex B is under investigation in clinical trial NCT03546621 (A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress H…

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Myricetin DB02375
small molecule | CAS: 529-44-2

Deskripsi belum tersedia.

Kategori:
BenzopyransChromonesHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformTyrosine-protein kinase JAK1
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Myristalkonium DB13774
small molecule | CAS: 16287-71-1

Deskripsi belum tersedia.

Kategori:
Anti-Infective Agents, LocalThroat Preparations
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Myristic acid DB08231
small molecule | CAS: 544-63-8

Deskripsi belum tersedia.

Kategori:
Fatty AcidsLipidsMyristic Acids
Target Protein:
Tyrosine-protein kinase ABL1Calmodulin-1Calmodulin-3 +45
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Myristoyl-Coa DB02180
small molecule | CAS: 3130-72-1

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
Glycylpeptide N-tetradecanoyltransferaseGlycylpeptide N-tetradecanoyltransferase 2
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small molecule | CAS: 1561-06-4

Deskripsi belum tersedia.

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Myrtecaine DB15785
small molecule | CAS: 7712-50-7

Deskripsi belum tersedia.

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Myxopyronin B DB08226
small molecule

Deskripsi belum tersedia.

Kategori:
DNA-Directed RNA Polymerases, antagonists & inhibitors
Target Protein:
DNA-directed RNA polymerase subunit alphaDNA-directed RNA polymerase subunit betaDNA-directed RNA polymerase subunit beta' +2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase 2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase 2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Ephrin type-B receptor 4
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