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16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
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112 (0.7%)
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16004 (100.0%)

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Hasil Pencarian (16004)

Halaman 182 / 321
biotech | CAS: 2538429-16-0

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
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Izaflortaucipir DB18282
small molecule | CAS: 2173361-80-1

Deskripsi belum tersedia.

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Izencitinib DB16660
small molecule | CAS: 2051918-33-1

Izencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).

Kategori:
Colitis, Ulcerative, drug therapyHeterocyclic Compounds, Fused-Ring
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Izokibep DB19081
biotech | CAS: 2226130-02-3

Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).

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Izuralimab DB18933
biotech | CAS: 2329669-80-7

Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).

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J147 DB13957
small molecule | CAS: 1146963-51-0

J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially develo…

Kategori:
AlkanesBenzene DerivativesCatechols +4
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JAB-21822 DB17478
small molecule

JAB-21822 is an oral small-molecule KRAS G12C inhibitor.

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JAB-3068 DB17131
small molecule

Deskripsi belum tersedia.

Target Protein:
Tyrosine-protein phosphatase non-receptor type 11
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JAK4D DB18527
small molecule | CAS: 882400-49-9

JAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.

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Janagliflozin DB16209
small molecule | CAS: 1800115-22-3

Janagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin).

Kategori:
AlcoholsCarbohydratesCyclohexanes +2
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Janssen COVID-19 Vaccine Approved DB15857
biotech

The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharma…

Kategori:
Biological ProductsComplex MixturesCOVID-19 Vaccines +2
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biotech

Deskripsi belum tersedia.

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biotech

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Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +3
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biotech

Deskripsi belum tersedia.

Kategori:
Inactivated Japanese Encephalitis Virus Vaccine
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JB991 DB05081
small molecule

JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely related cyclopentenone prostaglandin…

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JBI-778 DB18074
small molecule

Deskripsi belum tersedia.

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JBI-802 DB17399
small molecule

Deskripsi belum tersedia.

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JBPOS0101 DB16034
small molecule | CAS: 1353949-71-9

JBPOS0101 is under investigation in clinical trial NCT03976076 (A Study of Orally Administered JBPOS0101 in Refractory Infantile Spasms Patients).

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JE-2147 DB02668
small molecule | CAS: 186538-00-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmino Acids, Peptides, and ProteinsAntiviral Agents +4
Target Protein:
Gag-Pol polyproteinGag-Pol polyprotein
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JHU-75528 C-11 DB14902
small molecule | CAS: 942063-86-7

JHU-75528 C-11 is under investigation in clinical trial NCT03204305 (Brain Imaging of Cannabinoid Receptors).

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JLK-247 DB17637
biotech

JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.[L46686]

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JNJ-17216498 DB17087
small molecule | CAS: 1035626-05-1

JNJ-17216498 is a histamine receptor H3 antagonist developed by Johnson and Johnson for the treatment of narcolepsy.[A253997]

Target Protein:
Histamine H3 receptor
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JNJ-1802 DB17734
small molecule | CAS: 2043343-94-6

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
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JNJ-26489112 DB15203
small molecule | CAS: 871824-55-4

JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy).

Kategori:
AmidesAnticonvulsantsCentral Nervous System Depressants +2
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JNJ-27390467 DB06962
small molecule | CAS: 1025795-11-2

JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.

Target Protein:
Tryptase beta-2
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JNJ-27548547 DB15372
small molecule | CAS: 303983-00-8

JNJ-27548547 is under investigation in clinical trial NCT01705002 (Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.).

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JNJ-28312141 DB17140
small molecule | CAS: 885692-52-4

Deskripsi belum tersedia.

Kategori:
Receptors, Colony-Stimulating Factor, antagonists & inhibitors
Target Protein:
NT-3 growth factor receptorMast/stem cell growth factor receptor KitTyrosine-protein kinase Lck +1
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JNJ-28330835 DB13936
small molecule | CAS: 888072-47-7

A selective androgen receptor modulator with minimal prostate hypertrophic activity, enhances lean body mass in male rats and stimulates sexual behavior in female rats.

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JNJ-37822681 DB12579
small molecule | CAS: 935776-74-2

JNJ-37822681 has been used in trials studying the treatment of Schizophrenia.

Kategori:
Dopamine AgentsDopamine AntagonistsDopamine D2 Receptor Antagonists +1
Target Protein:
D(2) dopamine receptor
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JNJ-38877605 DB13113
small molecule | CAS: 943540-75-8

JNJ-38877605 has been used in trials studying the treatment of Neoplasms.

Target Protein:
Hepatocyte growth factor receptor
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JNJ-38877618 DB16883
small molecule | CAS: 943540-74-7

Deskripsi belum tersedia.

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JNJ-39220675 DB12929
small molecule | CAS: 959740-39-7

JNJ-39220675 has been used in trials studying the treatment of Allergic Rhinitis.

Kategori:
Histamine H3 Antagonists
Target Protein:
Histamine H3 receptor
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JNJ-39393406 DB11867
small molecule | CAS: 953428-73-4

JNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.

Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
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JNJ-39758979 DB18899
small molecule | CAS: 1046447-90-8

JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).

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JNJ-40346527 DB12504
small molecule | CAS: 1142363-52-7

JNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.

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JNJ-40411813 DB12059
small molecule | CAS: 1127498-03-6

JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.

Kategori:
Pyridines
Target Protein:
Metabotropic glutamate receptor 2
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JNJ-41443532 DB12632
small molecule | CAS: 1228650-83-6

JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.

Kategori:
Acids, CarbocyclicAmidesAzetines +2
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JNJ-42165279 DB15173
small molecule | CAS: 1346528-50-4

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).

Kategori:
Enzyme Inhibitors
Target Protein:
Fatty-acid amide hydrolase 1
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JNJ-42396302 DB12657
small molecule | CAS: 1298030-18-8

Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).

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JNJ-54175446 DB15358
small molecule | CAS: 1627902-21-9

JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid and Plasma).

Target Protein:
P2X purinoceptor 7
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JNJ-55308942 DB19110
small molecule | CAS: 2166558-11-6

JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

Kategori:
Neurotransmitter AgentsPurinergic AgentsPurinergic Antagonists +2
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JNJ-75276617 DB17574
small molecule

JNJ-75276617 is under investigation in clinical trial NCT05453903 (A Study of JNJ-75276617 in Combination With Acute Myeloid Leukemia (AML) Directed Therapies).

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JNT-517 DB19305
small molecule | CAS: 2837993-05-0

Deskripsi belum tersedia.

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Jojoba oil Approved DB14252
biotech | CAS: 61789-91-1

Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsCosmeticsLipids +3
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Josamycin DB01321
small molecule | CAS: 16846-24-5

A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +5
Target Protein:
50S ribosomal protein L4
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small molecule | CAS: 40922-77-8

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsLactonesMacrolides +1
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JPC-3210 DB15609
small molecule | CAS: 1609655-35-7

JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant _Plasmodium falciparum_ lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable…

Kategori:
AntimalarialsAntiviral AgentsBenzene Derivatives
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JQ1 DB17021
small molecule | CAS: 1268524-70-4

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

Target Protein:
Bromodomain-containing protein 4Bromodomain testis-specific protein
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JS-K DB17257
small molecule | CAS: 205432-12-8

Deskripsi belum tersedia.

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small molecule | CAS: 244218-93-7

An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.[A253027]

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
Nociceptin receptor
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