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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (13591)

Halaman 178 / 272
Monobenzone Approved DB00600
small molecule | CAS: 103-16-2

Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammal…

Kategori:
alpha-Galactosidase, antagonists & inhibitorsBenzene DerivativesDepigmenting Agents +3
Target Protein:
Tyrosinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Monoctanoin DB06801
small molecule | CAS: 502-54-5

Monoctanoin is used to dissolve cholesterol gallstones.

Kategori:
Acids, AcyclicFatty AcidsLipids +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15181-43-8

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +10
Target Protein:
Glycogen phosphorylase, muscle form
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesGlycoconjugatesGlycolipids +1
Target Protein:
Photosystem II protein D1 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAntigensAntigens, Bacterial +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 532-40-1

Deskripsi belum tersedia.

Kategori:
MicronutrientsPyrimidinesSulfur Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Monopotassium phosphate Approved DB09413
small molecule | CAS: 7778-77-0

Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion. It is a source of phosphorus and potassium as well as a buffering agent. It ca…

Kategori:
AcidsAcids, NoncarboxylicAnions +15
Waktu ParuhIn healthy children…
Vol. DistribusiPotassium first ent…
KlirensPhosphates are rapi…
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesSugar Alcohols +1
Target Protein:
Prolyl endopeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Monoxerutin DB13764
small molecule | CAS: 23869-24-1

Monoxerutin is a flavonol, a type of flavonoid.

Kategori:
Capillary Stabilizing AgentsFlavonoidsVasoprotectives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Montelukast Approved DB00471
small molecule | CAS: 158966-92-8

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.[L6301] The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capab…

Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityAgents to Treat Airway Disease +29
Target Protein:
Cysteinyl leukotriene receptor 1Polyunsaturated fatty acid 5-lipoxygenase
Waktu ParuhStudies have demons…
Vol. DistribusiThe steady-state vo…
KlirensThe plasma clearanc…
Genetik -
Monteplase DB12726
biotech | CAS: 156616-23-8

Monteplase has been used in trials studying the treatment of Pulmonary Embolism.

Kategori:
Amino Acids, Peptides, and ProteinsAnticoagulantsBlood Proteins +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Montmorillonite DB13654
small molecule | CAS: 1318-93-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Silicates +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moperone DB13554
small molecule | CAS: 1050-79-9

Deskripsi belum tersedia.

Kategori:
Antipsychotic AgentsButyrophenone DerivativesCentral Nervous System Depressants +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
MORAb-066 DB17347
biotech

MORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Morclofone DB13558
small molecule | CAS: 31848-01-8

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesCough and Cold PreparationsKetones
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moricizine Approved DB00680
small molecule | CAS: 31883-05-3

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.

Kategori:
Antiarrhythmic agentsAntiarrhythmics, Class IAntiarrhythmics, Class Ic +15
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu Paruh2 hours (range 1.5-…
Vol. Distribusi* 300 L
Klirens-
Genetik -
Morin DB16770
small molecule | CAS: 480-16-0

Deskripsi belum tersedia.

Kategori:
AntioxidantsBenzopyransBiological Factors +8
Target Protein:
Estrogen receptor betaSolute carrier family 22 member 12Fatty acid synthase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Morinamide DB13417
small molecule | CAS: 952-54-5

Deskripsi belum tersedia.

Kategori:
Antiinfectives for Systemic UseAntimycobacterialsDrugs for Treatment of Tuberculosis
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Moringa oleifera leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Morinidazole DB15098
small molecule | CAS: 92478-27-8

Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis).

Kategori:
ImidazolesNitro Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moroctocog alfa Approved DB13999
biotech | CAS: 284036-24-4

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is …

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +5
Target Protein:
Coagulation factor XCoagulation factor IXvon Willebrand factor +8
Waktu ParuhMean terminal elimi…
Vol. DistribusiMean steady-state v…
KlirensMean clearance = 4.…
Genetik -
Moroxydine DB13597
small molecule | CAS: 3731-59-7

Deskripsi belum tersedia.

Kategori:
AmidinesAnti-Infective AgentsAntiinfectives for Systemic Use +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Morphine Approved DB00295
small molecule | CAS: 57-27-2

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.[A176050] Morphine is still routinely used today, though there …

Kategori:
AlkaloidsAnalgesicsAnesthetics +25
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor +1
Gen Terkait:
ABCB1 OPRM1
Waktu ParuhMorphine has a half…
Vol. DistribusiThe volume of distr…
KlirensThe apparent cleara…
Genetik 2 Varian
Morpholine DB13669
small molecule | CAS: 110-91-8

Deskripsi belum tersedia.

Kategori:
AnalgesicsNervous SystemOxazines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin S
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin S
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin S
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 102-77-2

Deskripsi belum tersedia.

Kategori:
Cell-mediated ImmunityHeterocyclic Compounds, Fused-RingIncreased Histamine Release +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Morus rubra pollen Approved DB10373
biotech

Morus rubra pollen is the pollen of the Morus rubra plant. Morus rubra pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mosapramine DB13676
small molecule | CAS: 89419-40-9

Deskripsi belum tersedia.

Kategori:
Antipsychotic AgentsCentral Nervous System DepressantsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mosapride DB11675
small molecule | CAS: 112885-41-3

Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspe…

Kategori:
Acids, CarbocyclicAlimentary Tract and MetabolismAmides +13
Target Protein:
5-hydroxytryptamine receptor 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mosedipimod DB12592
small molecule | CAS: 221139-79-3

Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.

Kategori:
Experimental Unapproved Treatments for COVID-19Lipids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mosliciguat DB19425
small molecule | CAS: 2231749-54-3

Mosliciguat is under investigation in clinical trial NCT06635850 (A Phase 2 Study of Mosliciguat in PH-ILD).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mosunetuzumab Approved DB15434
biotech | CAS: 1905409-39-3

Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody.[L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells.[A249320] The …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +13
Target Protein:
B-lymphocyte antigen CD20T-cell surface glycoprotein CD3 epsilon chain
Waktu ParuhMosunetuzumab has a…
Vol. DistribusiThe estimated centr…
KlirensThe mean steady-sta…
Genetik -
Motavizumab DB06310
biotech | CAS: 677010-34-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Motesanib DB05575
small molecule | CAS: 453562-69-1

Deskripsi belum tersedia.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingNicotinic Acids +3
Target Protein:
Vascular endothelial growth factor receptor 2Mast/stem cell growth factor receptor Kit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Motixafortide Approved DB14939
biotech | CAS: 664334-36-5

Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation.[L48116] Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - h…

Kategori:
Amino Acids, Peptides, and ProteinsHematopoietic Stem Cell MobilizerPeptides
Target Protein:
C-X-C chemokine receptor type 4
Waktu ParuhThe effective half-…
Vol. DistribusiIn a typical patien…
KlirensIn a typical patien…
Genetik -
Motolimod DB12303
small molecule | CAS: 926927-61-9

Motolimod has been used in trials studying the treatment of Lymphoma, Tongue Cancer, Ovarian Cancer, Adult Solid Neoplasm, and Fallopian Tube Cancer, among others.

Kategori:
Heterocyclic Compounds, Fused-RingToll-Like Receptor 8, agonists
Target Protein:
Toll-like receptor 8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Motretinide DB13368
small molecule | CAS: 56281-36-8

Deskripsi belum tersedia.

Kategori:
AlkenesAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Motuporin DB04738
small molecule | CAS: 141672-08-4

Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey.

Kategori:
Amino Acids, Peptides, and ProteinsCytotoxinsPeptides
Target Protein:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moxaverine DB12251
small molecule | CAS: 10539-19-2

Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.

Kategori:
Alimentary Tract and MetabolismAlkaloidsAutonomic Agents +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moxestrol DB13418
small molecule | CAS: 34816-55-2

Deskripsi belum tersedia.

Kategori:
Estradiol CongenersEstrogen AntagonistsEstrogenic Steroids, Alkylated +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Moxetumomab pasudotox Approved DB12688
biotech | CAS: 1020748-57-5

CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created b…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +18
Target Protein:
B-cell receptor CD22Elongation factor 2
Waktu ParuhMxP presents a shor…
Vol. DistribusiThe mean volume of …
KlirensThe mean systemic c…
Genetik -
Moxidectin Approved DB11431
small molecule | CAS: 113507-06-5

Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-sy…

Kategori:
AgrochemicalsAnthelminticsAnti-Infective Agents +9
Target Protein:
Glutamate-gated chloride channelGABA-A gated chloride channelABC transporters
Waktu ParuhMoxidectin reporter…
Vol. DistribusiMoxidectin presents…
KlirensThe apparent cleara…
Genetik -
Moxifloxacin Approved DB00218
small molecule | CAS: 151096-09-2

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +18
Target Protein:
DNA gyrase subunit ADNA gyrase subunit BDNA gyrase subunit A +3
Waktu Paruh11.5-15.6 hours (si…
Vol. Distribusi* 1.7 to 2.7 L/kg
Klirens* 12 +/- 2 L/hr
Genetik -
Moxisylyte Approved DB09205
small molecule | CAS: 54-32-0

Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active ?1-adrenergic antagonist.[T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired the denomination of orphan product by the FDA.[L117…

Kategori:
Adrenergic AgentsAdrenergic alpha-AntagonistsAdrenergic Antagonists +17
Target Protein:
Alpha-1D adrenergic receptorAlpha adrenergic receptor
Waktu ParuhThe half-life of mo…
Vol. DistribusiIn preclinical tria…
KlirensIn preclinical tria…
Genetik -
Moxonidine Approved DB09242
small molecule | CAS: 75438-57-2

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calc…

Kategori:
Adrenergic AgonistsAdrenergic alpha-2 Receptor AgonistsAdrenergic alpha-Agonists +8
Target Protein:
Alpha-2C adrenergic receptorAlpha-2B adrenergic receptorAlpha-2A adrenergic receptor +1
Waktu ParuhPlasma elimination …
Vol. Distribusi1.8±0.4L/kg. [FDA l…
KlirensAdministered twice …
Genetik -
biotech

RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mozenavir DB02102
small molecule | CAS: 174391-92-5

Deskripsi belum tersedia.

Kategori:
Amides
Target Protein:
Gag-Pol polyproteinGag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
MP-0250 DB17218
biotech | CAS: 1816305-70-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsProteinsRecombinant Proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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