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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Hasil Pencarian (15718)

Halaman 176 / 315
KIT-13 DB18093
small molecule | CAS: 103628-72-4

Deskripsi belum tersedia.

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Kitasamycin DB09309
small molecule | CAS: 1392-21-8

Kitasamycin is a macrolide antibiotic derived from <em>Streptomyces kitasatoensis</em>.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsCytochrome P-450 CYP3A Inhibitors +7
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KITE-222 DB17195
biotech

Deskripsi belum tersedia.

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KITE-585 DB17409
biotech

KITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.

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Kiwi fruit Approved DB10641
biotech

Kiwi fruit allergenic extract is used in allergenic testing.

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KL1333 DB17622
small molecule | CAS: 1800405-30-4

Deskripsi belum tersedia.

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KN-001 DB18495
small molecule

Deskripsi belum tersedia.

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Koeleria macrantha pollen Approved DB10949
biotech

Koeleria macrantha pollen is the pollen of the Koeleria macrantha plant. Koeleria macrantha pollen is mainly used in allergenic testing.

Kategori:
Allergenic ExtractsCell-mediated ImmunityGrass Pollen Allergen Extracts +3
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Kojic acid DB01759
small molecule | CAS: 501-30-4

Deskripsi belum tersedia.

Kategori:
AntioxidantsBiological FactorsCompounds used in a research, industrial, or household setting +3
Target Protein:
Tyrosinase
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Konjac mannan DB14963
small molecule | CAS: 37220-17-0

Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).

Kategori:
CarbohydratesGastrointestinal AgentsLaxatives +2
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KOS-1584 DB05903
small molecule | CAS: 350493-61-7

KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue …

Kategori:
Anti-Bacterial AgentsAntineoplastic AgentsCytochrome P-450 CYP3A Inhibitors +6
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KOS-2187 DB05946
small molecule

KOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease (GERD).

Target Protein:
Promotilin
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KOSN-1724 DB13078
small molecule | CAS: 693272-98-9

KOSN-1724 is under investigation in clinical trial NCT01379287 (Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors).

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KP-1461 DB05644
small molecule | CAS: 815588-85-3

KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue. Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases.

Kategori:
CarbohydratesGlycosidesNucleic Acids, Nucleotides, and Nucleosides
Target Protein:
Gag-Pol polyprotein
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KP1237 DB18401
biotech

KP1237 is a antibody-redirecting molecule composed of two binding sites (a CD38 binder and a universal antibody binding terminus binder) connected by a linker chain.

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biotech

Krascheninnikovia lanata pollen is the pollen of the Krascheninnikovia lanata plant. Krascheninnikovia lanata pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Krill oil DB16615
biotech

Deskripsi belum tersedia.

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KRN-330 DB19075
biotech

Anti-a33 fully-human monoclonal antibody is under investigation in clinical trial NCT00838578 (Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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KRN-5500 DB15215
small molecule | CAS: 151276-95-8

KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).

Kategori:
Antineoplastic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +4
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KRN-7000 DB12232
small molecule | CAS: 158021-47-7

KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.

Kategori:
Adjuvants, ImmunologicAmidesAntineoplastic Agents +11
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Krypton Kr 81m Approved DB09443
small molecule | CAS: 15678-91-8

Deskripsi belum tersedia.

Kategori:
Diagnostic Radiopharmaceuticals
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KT-253 DB18487
small molecule

KT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).

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KT-333 DB17165
small molecule

KT-333 is a small molecule targeted protein degrader of STAT3.[L44086]

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KT-A261 DB19317
biotech

KT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.

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KTH-222 DB17314
biotech

Deskripsi belum tersedia.

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KTX-1001 DB18171
small molecule

Deskripsi belum tersedia.

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KUR-113 DB18413
biotech

KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.

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small molecule | CAS: 1357245-09-0

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicSulfur Acids +1
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small molecule | CAS: 904899-25-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyrazoles
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
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KW-6356 DB17080
small molecule

KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

Target Protein:
Adenosine receptor A2a
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KW-7158 DB05498
small molecule

KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The the…

Kategori:
Heterocyclic Compounds, Fused-RingSulfur Compounds
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KX-2361 DB17180
small molecule | CAS: 897016-26-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +6
Target Protein:
Proto-oncogene tyrosine-protein kinase Src
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Kynurenic Acid DB11937
small molecule | CAS: 492-27-3

Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).

Kategori:
Excitatory Amino Acid AgentsExcitatory Amino Acid AntagonistsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2BGlutamate receptor ionotropic, NMDA 2A +2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
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small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
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small molecule | CAS: 1758-80-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Envelope glycoprotein gp160
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small molecule | CAS: 73537-09-4

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Cysteine desulfuraseCystathionine gamma-lyase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
S-adenosylmethionine synthase isoform type-1
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small molecule | CAS: 26630-55-7

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDicarboxylic Acids
Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
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L-377202 DB19022
small molecule | CAS: 207395-85-5

L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).

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L-3972-T DB17441
biotech | CAS: 2170699-22-4

L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.

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L-709,587 DB03621
small molecule

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1A
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L-756423 DB02009
small molecule | CAS: 216863-66-0

Deskripsi belum tersedia.

Kategori:
Antiviral AgentsHIV Protease InhibitorsIndenes
Target Protein:
Gag-Pol polyprotein
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L-778123 DB07227
small molecule | CAS: 183499-57-2

Deskripsi belum tersedia.

Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-1 subunit beta
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L-Acetylleucine Approved DB16956
small molecule | CAS: 1188-21-2

Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo.[A264439] Observational studies in patients with Niemann-Pi…

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +7
Waktu ParuhThe half-life of le…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Kallikrein-7
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small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 1509-34-8

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins
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small molecule | CAS: 33049-08-0

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small molecule | CAS: 1006685-44-4

C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal muscle breakdown. C-101 includes a carnitine carrier mole…

Target Protein:
Calpain-3
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