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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 172 / 349
GW842166 DB11903
small molecule | CAS: 666260-75-9

GW842166X has been used in trials studying the treatment of Pain, Analgesia, Inflammation, Osteoarthritis, and Pain, Inflammatory, among others.

Kategori:
Agents producing tachycardiaCannabinoid Receptor AgonistsCannabinoids and similars +1
Target Protein:
Cannabinoid receptor 2
Waktu Paruh-
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GX-19 Vaccine DB15891
biotech

The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

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GX-G8 DB18196
biotech

GX-G8 is a long-acting glucagon-like peptide 2 (GLP-2) being investigated for the treatment of short bowel syndrome.

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GXC-301 DB18831
biotech

Deskripsi belum tersedia.

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GYM329 DB18590
biotech

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner

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GZ-389988 DB16056
small molecule | CAS: 1788906-96-6

GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee).

Target Protein:
NT-3 growth factor receptorHigh affinity nerve growth factor receptorBDNF/NT-3 growth factors receptor
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small molecule

Deskripsi belum tersedia.

Target Protein:
Histo-blood group ABO system transferase
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H-89 DB07995
small molecule | CAS: 127243-85-0

Deskripsi belum tersedia.

Kategori:
AmidesEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +3
Target Protein:
cAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase inhibitor alphaSerine/threonine-protein kinase haspin +1
Waktu Paruh-
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H3B-6527 DB15169
small molecule | CAS: 1702259-66-2

H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Fibroblast growth factor receptor 4
Waktu Paruh-
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H3B-8800 DB14017
small molecule | CAS: 1825302-42-8

H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551]. It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferent…

Target Protein:
Splicing factor 3B subunit 1
Waktu Paruh-
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Hachimycin DB13302
small molecule | CAS: 1394-02-1

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntifungals for Dermatological UseAntifungals for Topical Use +6
Waktu Paruh-
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Hadacidin DB02109
small molecule | CAS: 689-13-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAntibiotics, Antineoplastic +4
Target Protein:
Inosine-5'-monophosphate dehydrogenase 1Adenylosuccinate synthetaseAdenylosuccinate synthetase +1
Waktu Paruh-
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Haddock Approved DB10615
biotech

Haddock allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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biotech

Deskripsi belum tersedia.

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biotech

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Haemagglutinin-strain B Approved DB15482
biotech

Deskripsi belum tersedia.

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biotech

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biotech

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Haematonectria haematococca Approved DB10934
biotech

Haematonectria haematococca is a fungus which can provoke allergic reactions. Haematonectria haematococca extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Deskripsi belum tersedia.

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biotech

Haemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigen is a vaccine containing outer membrane antigen extracted from *Haemophilus influenzae*.

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine
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biotech

Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by *Haemophilus influenzae* type b. *H. influenzae* is a Gram-negativ…

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine
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biotech

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vacci…

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine +2
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Hafnium oxide DB17508
small molecule | CAS: 12055-23-1

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesElements +5
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Halazepam Approved DB00801
small molecule | CAS: 23092-17-3

Halazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam.[A1212] This drug is no longer marketed in the Unite…

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepines and benzodiazepine derivatives +7
Target Protein:
Translocator proteinGABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
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Halcinonide Approved DB06786
small molecule | CAS: 3093-35-4

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Labora…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +13
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
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Haletazole DB15942
small molecule | CAS: 15599-36-7

Deskripsi belum tersedia.

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Halicin DB15624
small molecule | CAS: 40045-50-9

Deskripsi belum tersedia.

Kategori:
Sulfur CompoundsThiazoles
Target Protein:
c-Jun N-terminal kinases
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Halofantrine Approved DB01218
small molecule | CAS: 69756-53-2

Halofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poiso…

Kategori:
Agents that reduce seizure thresholdAnti-Infective AgentsAntimalarials +13
Target Protein:
Fe(II)-protoporphyrin IXCalmodulin-1Calmodulin-3 +3
Waktu Paruh6-10 days
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Halofuginone DB04866
small molecule | CAS: 55837-20-2

Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Bio…

Kategori:
Angiogenesis InhibitorsAngiogenesis Modulating AgentsAnti-Infective Agents +10
Target Protein:
Collagen alpha-1(I) chain72 kDa type IV collagenase
Waktu Paruh23.8 to 72.1 hours
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Halometasone DB13728
small molecule | CAS: 50629-82-8

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroids +19
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Haloperidol Approved DB00502
small molecule | CAS: 52-86-8

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.[A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A274…

Kategori:
Agents that reduce seizure thresholdAnti-Dyskinesia AgentsAntidepressive Agents +50
Target Protein:
5-hydroxytryptamine receptor 2CD(2) dopamine receptor5-hydroxytryptamine receptor 2A +15
Waktu ParuhFollowing oral admi…
Vol. DistribusiThe apparent volume…
KlirensFollowing intraveno…
Genetik -
Haloprogin Approved DB00793
small molecule | CAS: 777-11-7

Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Com…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +5
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Halothane Approved DB01159
small molecule | CAS: 151-67-7

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxatio…

Kategori:
Agents that produce hypertensionAnestheticsAnesthetics, General +14
Target Protein:
Potassium channel subfamily K member 3Potassium channel subfamily K member 9GABA(A) Receptor +14
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Haloxazolam DB01476
small molecule | CAS: 59128-97-1

Deskripsi belum tersedia.

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
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Haloxon DB11419
small molecule | CAS: 321-55-1

Deskripsi belum tersedia.

Kategori:
BenzopyransCoumarinsHeterocyclic Compounds, Fused-Ring +1
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Haloxyfop-P DB07870
small molecule | CAS: 95977-29-0

Deskripsi belum tersedia.

Target Protein:
Acetyl-CoA carboxylase 2
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biotech

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biotech

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biotech

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Hard fat Approved DB11578
small molecule

Deskripsi belum tersedia.

Kategori:
Pharmaceutical Vehicles
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Harmaline DB13875
small molecule | CAS: 304-21-2

Deskripsi belum tersedia.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAlkaloids +14
Target Protein:
Histamine N-methyltransferase
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Harmine DB07919
small molecule | CAS: 442-51-3

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntidepressive AgentsCarbolines +13
Target Protein:
Dual specificity tyrosine-phosphorylation-regulated kinase 2Dual specificity tyrosine-phosphorylation-regulated kinase 3Dual specificity tyrosine-phosphorylation-regulated kinase 1A +1
Waktu Paruh-
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biotech

Deskripsi belum tersedia.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +10
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Hazelnut Approved DB10654
biotech

Hazelnut allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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HCV-086 DB05884
small molecule

HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.

Target Protein:
Genome polyprotein
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HE-2200 DB06257
small molecule | CAS: 2697-85-0

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesFused-Ring Compounds +1
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HE3286 DB05212
small molecule | CAS: 1001100-69-1

Deskripsi belum tersedia.

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12
Target Protein:
Nuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit
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Genetik -
biotech

Heat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine.

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biotech

Hedera helix leaf extract allergenic extract is used in allergenic testing.

Kategori:
Cough and Cold PreparationsExpectorants
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