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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (13591)

Halaman 172 / 272
Methotrimeprazine Approved DB01403
small molecule | CAS: 60-99-1

A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Mart…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +46
Target Protein:
D(2) dopamine receptorD(1A) dopamine receptorD(1B) dopamine receptor +16
Waktu ParuhApproximately 20 ho…
Vol. Distribusi-
Klirens-
Genetik -
Methoxamine Approved DB00723
small molecule | CAS: 390-28-3

An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +19
Target Protein:
Alpha-1A adrenergic receptorAlpha-1D adrenergic receptorAlpha-1B adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methoxsalen Approved DB00553
small molecule | CAS: 298-81-7

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.

Kategori:
AntipsoriaticsAntipsoriatics for Systemic UseAntipsoriatics for Topical Use +24
Target Protein:
DNACytochrome P450 2A6
Waktu ParuhApproximately 2 hou…
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 180509-15-3

Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid amide hydrolase with specia…

Kategori:
EicosanoidsEnzyme InhibitorsFatty Acids +5
Target Protein:
Fatty-acid amide hydrolase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 677324-53-7

Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsAntianemic Preparations +20
Target Protein:
Erythropoietin receptor
Waktu ParuhIn CKD patients on …
Vol. Distribusi~94.74 ml/kg
KlirensIn CKD patients on …
Genetik -
Methoxyamine DB06328
small molecule | CAS: 67-62-9

Deskripsi belum tersedia.

Kategori:
Amines
Target Protein:
DNA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methoxyflurane Approved DB01028
small molecule | CAS: 76-38-0

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agen…

Kategori:
Agents that produce hypertensionAnalgesicsAnesthetics +18
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Glutamate receptor 1Glycine receptor subunit alpha-1 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methoxyphenamine Approved DB13624
small molecule | CAS: 93-30-1

Deskripsi belum tersedia.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-Agonists +12
Target Protein:
Beta-2 adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methscopolamine Approved DB11315
small molecule | CAS: 13265-10-6

Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunc…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAlkaloids +16
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methsuximide Approved DB05246
small molecule | CAS: 77-41-8

Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.

Kategori:
Agents causing hyperkalemiaAnti-epileptic AgentAntiarrhythmic agents +18
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1G
Waktu Paruh1.4-2.6 hours for m…
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 135-07-9

A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)

Kategori:
BenzothiadiazinesDiureticsDrugs causing inadvertant photosensitivity +12
Target Protein:
Solute carrier family 12 member 1Carbonic anhydrase 1Carbonic anhydrase 2 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 193744-04-6

This solid compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl group…

Target Protein:
Interleukin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cytochrome c1, heme protein, mitochondrialCytochrome bCytochrome b-c1 complex subunit 1, mitochondrial +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Polyhydroxybutyrate depolymerase, putative
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Caspase-3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 63177-57-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAntineoplastic AgentsCompounds used in a research, industrial, or household setting +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-betaEndoplasmin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serum amyloid P-component
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lactoylglutathione lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Dipeptidyl peptidase 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34004-14-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methyl aminolevulinate Approved DB00992
small molecule | CAS: 33320-16-0

Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAntineoplastic Agents +11
Target Protein:
Ferrochelatase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2044523-17-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 709-50-2

Deskripsi belum tersedia.

Kategori:
CarbohydratesGlucosidesGlycosides +1
Target Protein:
Endoglucanase 5AEndoglucanase FPossible cellulase CelA1 (Endoglucanase) (Endo-1,4-beta-glucanase) (FI-cmcase) (Carboxymethyl cellulase)
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24332-98-7

Deskripsi belum tersedia.

Target Protein:
Mannose-binding protein C
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 624-83-9

Methyl isocyanate has been investigated for the treatment of Nosocomial Pneumonia.

Kategori:
Antisickling AgentsHematologic Agents
Target Protein:
Transient receptor potential cation channel subfamily A member 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2577-90-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +1
Target Protein:
ProthrombinFimbrial protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 33577-16-1

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methyl nicotinate Approved DB13882
small molecule | CAS: 93-60-7

Methyl nicotinate is the methyl ester of [DB00627] that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve perip…

Kategori:
Anti-Inflammatory AgentsErythemaInflammation +2
Waktu Paruh_In vitro_, the hal…
Vol. DistribusiAccording to the an…
KlirensNo pharmacokinetic …
Genetik -
small molecule | CAS: 1731-84-6

Deskripsi belum tersedia.

Target Protein:
Immunoglobulin heavy constant gamma 1Neutrophil gelatinase-associated lipocalin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methyl red DB08209
small molecule | CAS: 493-52-7

Deskripsi belum tersedia.

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household setting
Target Protein:
FMN-dependent NADH-azoreductase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methyl salicylate Approved DB09543
small molecule | CAS: 119-36-8

Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be ma…

Kategori:
Acids, CarbocyclicAnalgesicsAntirheumatic Agents +16
Target Protein:
Transient receptor potential cation channel subfamily A member 1
Waktu ParuhThe plasma half-lif…
Vol. DistribusiAfter absorption, m…
Klirens-
Genetik -
small molecule | CAS: 85005-92-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1246371-29-8

Methyl undecenoyl leucinate is an active ingredient in whitening creams. It is an ?-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.

Kategori:
Melanin Synthesis Inhibitor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3943-74-6

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +5
Target Protein:
Endo-1,4-beta-xylanase Y
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
DNA-directed RNA polymerase subunit alphaDNA-directed RNA polymerase subunit betaDNA-directed RNA polymerase subunit beta' +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 65-04-3

Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It is a derivative of 1-testosterone with a methyl group in the carbon 17. Methyl-1-testosterone is considered a prohibited dopi…

Kategori:
Testosterone and derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 50673-41-1

Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Immunoglobulin kappa constantAlkaline phosphatase, placental type
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Squalene--hopene cyclase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Neutrophil collagenaseInterstitial collagenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methylatropine DB13833
small molecule | CAS: 31610-87-4

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAlkaloidsAutonomic Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 13473-61-5

Deskripsi belum tersedia.

Kategori:
AminesAmmonium CompoundsNitrogen Compounds +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 76970-78-0

Methylcantharidimide is under investigation in clinical trial NCT03996681 (TACE Combined With Methylcantharidimide Tablets in the Treatment of Large and Unresectable Hepatocellular Carcinoma).

Kategori:
BenzofuransHeterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methylcellulose Approved DB11228
small molecule | CAS: 9004-67-5

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of subst…

Kategori:
Alimentary Tract and MetabolismBulk-Forming LaxativesCarbohydrates +7
Waktu Paruh4.2 minutes
Vol. Distribusiaccumulation in liv…
Klirens-
Genetik -
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