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807

Total database: 17430
Struktur (SMILES)
608 (75.3%)
Target
525 (65.1%)
Genomik
15 (1.9%)
Referensi
807 (100.0%)

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Hasil Pencarian (807)

Halaman 17 / 17
YSIL6 DB05017
small molecule

YSIL6 is a small-molecule drug in development for the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. The molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell prolife…

Target Protein:
Tumor necrosis factorInterleukin-6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Zafiride DB18371
biotech

Zafiride is a human tumor necrosis factor coupled to the C terminus of CNGRCG peptide.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Zeranol DB11478
small molecule | CAS: 26538-44-3

Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x more potent as an estrogen agonist than the related compound zearalenone.

Kategori:
Benzene DerivativesEstrogensEstrogens, Non-Steroidal +6
Target Protein:
Estrogen receptorSex hormone-binding globulin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Zilucoplan Approved DB15636
small molecule | CAS: 1841136-73-9

Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses.[A261841] On October 1…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating AgentsBlood Proteins +5
Target Protein:
Complement C5
Waktu ParuhThe mean plasma ter…
Vol. DistribusiThe mean volume of …
KlirensNo information is a…
Genetik -
Zuclopenthixol Approved DB01624
small molecule | CAS: 53772-83-1

Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine rece…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +34
Target Protein:
D(1A) dopamine receptorD(1B) dopamine receptorD(2) dopamine receptor +4
Waktu Paruh20 hours (range 12-…
Vol. Distribusi20 L/kg.
Klirensapproximately 0.9 L…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-lactamase TEM
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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