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15718

Total database: 17430
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10762 (68.5%)
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7957 (50.6%)
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112 (0.7%)
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15718 (100.0%)

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Halaman 169 / 315
biotech

Deskripsi belum tersedia.

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biotech

Deskripsi belum tersedia.

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Interleukin-7 DB11997
biotech | CAS: 858376-81-5

Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
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Intermedine DB17612
biotech | CAS: 581-05-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAmino Acids, Peptides, and ProteinsHeterocyclic Compounds, Fused-Ring +13
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Intetumumab DB12701
biotech | CAS: 725735-28-4

Intetumumab has been used in trials studying the treatment of Melanoma.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
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Intoplicine DB12868
small molecule | CAS: 125974-72-3

Intoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
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Inula helenium root Approved DB14350
biotech

Inula helenium root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Inupadenant DB19129
small molecule | CAS: 2246607-08-7

Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).

Target Protein:
Adenosine receptor A2a
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INVAC-1 DB16196
biotech | CAS: 1708137-44-3

INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

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Invert sugar DB09344
small molecule | CAS: 8013-17-0

Invert sugar is obtained from sugar cane when this is treated with dilute acid or with the invertase enzyme. It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case o…

Kategori:
Antivaricose TherapyCarbohydratesCariogenic Agents +14
Waktu ParuhThe glucose half-li…
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INZ-701 DB17629
biotech

INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.

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IO-202 DB17548
biotech

IO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.

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Iobenguane Approved DB06704
small molecule | CAS: 80663-95-2

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionu…

Kategori:
AmidinesBenzene DerivativesCompounds used in a research, industrial, or household setting +16
Target Protein:
Sodium-dependent noradrenaline transporter
Waktu ParuhPhysical half life …
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Iobenguane sulfate I-123 Approved DB09546
small molecule | CAS: 80663-95-2

Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].

Kategori:
Drugs that are Mainly Renally ExcretedRadioactive Diagnostic AgentRadiopharmaceutical Activity
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Iobenzamic acid DB13428
small molecule | CAS: 3115-05-7

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +7
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Iobitridol Approved DB12407
small molecule | CAS: 136949-58-1

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
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Iocarmic acid DB13755
small molecule | CAS: 10397-75-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +12
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Iocetamic acid Approved DB09403
small molecule | CAS: 16034-77-8

Iocetamic acid is a diagnostic aid (radiopaque medium)

Kategori:
Benzene DerivativesContrast MediaHydrocarbons, Halogenated +3
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Iodide Approved DB12754
small molecule | CAS: 20461-54-5

Iodide has been investigated for the treatment of Goiter, Nodular.

Kategori:
AnionsElectrolytesIodides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
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Iodide I-123 Approved DB09420
small molecule | CAS: 69239-56-1

Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid g…

Kategori:
Diagnostic RadiopharmaceuticalsElementsHalogens +6
Waktu ParuhIodine-123 decays b…
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Iodide I-131 Approved DB09293
small molecule | CAS: 14914-30-8

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result o…

Kategori:
Diagnostic RadiopharmaceuticalsIodine (131I) CompoundsRadioactive Therapeutic Agent +3
Waktu ParuhIodine I-131 decays…
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Iodine Approved DB05382
small molecule | CAS: 7553-56-2

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A1921…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +12
Target Protein:
Sodium/iodide cotransporterMicrobial proteins
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small molecule | CAS: 56897-09-7

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesDiagnostic Radiopharmaceuticals +6
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biotech | CAS: 2420475-06-3

Deskripsi belum tersedia.

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Iodine I-125 DB14804
small molecule | CAS: 14158-31-7

Iodine I-125 is under investigation in clinical trial NCT00079417 (Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma).

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biotech | CAS: 1000874-23-6

Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

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Iodine povacrylex Approved DB09537
small molecule | CAS: 845736-10-9

Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity. DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the prepara…

Kategori:
Anti-Infective Agents, Local
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
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Iodipamide Approved DB04711
small molecule | CAS: 606-17-7

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Target Protein:
Albumin
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Iodixanol Approved DB01249
small molecule | CAS: 92339-11-2

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu Paruh2.1 hours. In patie…
Vol. Distribusi* 0.26 L/kg
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small molecule

Deskripsi belum tersedia.

Target Protein:
Glutamate receptor ionotropic, kainate 1Glutamate receptor 2
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Iodobenzene DB02252
small molecule | CAS: 591-50-4

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated
Target Protein:
Endoglucanase F
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small molecule | CAS: 42220-21-3

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsIodine (131I) Compounds
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small molecule | CAS: 123748-56-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated +2
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Iodoform Approved DB13813
small molecule | CAS: 75-47-8

Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions [A32890]. Due to its antimicrobial properties following topi…

Kategori:
DermatologicalsHydrocarbons, HalogenatedMedicated Dressings +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Iodohippurate sodium I-123 Approved DB09448
small molecule | CAS: 56254-07-0

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsRenal System
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Iodohippurate sodium I-131 Approved DB09382
small molecule | CAS: 881-17-4

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsRenal System
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small molecule | CAS: 147-58-0

Iodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults).

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +7
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small molecule | CAS: 55406-53-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAllergensAntigens +1
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Iodoxamic acid DB13539
small molecule | CAS: 31127-82-9

Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
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Iofetamine I-123 Approved DB09480
small molecule | CAS: 75917-92-9

Deskripsi belum tersedia.

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +13
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small molecule | CAS: 1214283-52-9

Deskripsi belum tersedia.

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Ioflupane F-18 DB16913
small molecule | CAS: 186381-69-1

Deskripsi belum tersedia.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
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Ioflupane I-123 Approved DB08824
small molecule | CAS: 155798-07-5

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +9
Target Protein:
Sodium-dependent dopamine transporter
Waktu ParuhHalf life is 13.2 h…
Vol. DistribusiCompared to the ent…
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small molecule | CAS: 949575-24-0

Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

Kategori:
AmidesAmino AcidsAmino Acids, Acidic +2
Target Protein:
Glutamate carboxypeptidase 2
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Ioforminol DB12439
small molecule | CAS: 1095110-48-7

Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.

Kategori:
Acids, AcyclicAcids, CarbocyclicAmides +5
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Ioglicic acid DB13701
small molecule | CAS: 49755-67-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +5
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Ioglycamic acid DB13741
small molecule | CAS: 2618-25-9

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
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Iohexol Approved DB01362
small molecule | CAS: 66108-95-0

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmo…

Kategori:
Acids, CarbocyclicAgents that reduce seizure thresholdBenzene Derivatives +12
Waktu ParuhIntrathecal half-li…
Vol. Distribusi* 350-849 mL/kg
Klirens* 109 mL/min [Adult…
Genetik -
Iomazenil DB14971
small molecule | CAS: 127985-21-1

Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).

Kategori:
BenzazepinesBenzodiazepinonesHeterocyclic Compounds, Fused-Ring +1
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Iomeprol Approved DB11705
small molecule | CAS: 78649-41-9

Iomeprol has been investigated for the diagnostic of Coronary Artery Disease.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
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