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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 162 / 282
KOSN-1724 DB13078
small molecule | CAS: 693272-98-9

KOSN-1724 is under investigation in clinical trial NCT01379287 (Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors).

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KP1237 DB18401
biotech

KP1237 is a antibody-redirecting molecule composed of two binding sites (a CD38 binder and a universal antibody binding terminus binder) connected by a linker chain.

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KRN-5500 DB15215
small molecule | CAS: 151276-95-8

KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).

Kategori:
Antineoplastic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +4
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KRN-7000 DB12232
small molecule | CAS: 158021-47-7

KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.

Kategori:
Adjuvants, ImmunologicAmidesAntineoplastic Agents +11
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KT-253 DB18487
small molecule

KT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).

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KT-A261 DB19317
biotech

KT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.

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KTH-222 DB17314
biotech

Deskripsi belum tersedia.

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Genetik -
KTX-1001 DB18171
small molecule

Deskripsi belum tersedia.

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Genetik -
small molecule | CAS: 1357245-09-0

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicSulfur Acids +1
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Genetik -
small molecule | CAS: 904899-25-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyrazoles
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
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KW-6356 DB17080
small molecule

KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

Target Protein:
Adenosine receptor A2a
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KX-2361 DB17180
small molecule | CAS: 897016-26-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +6
Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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Kynurenic Acid DB11937
small molecule | CAS: 492-27-3

Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).

Kategori:
Excitatory Amino Acid AgentsExcitatory Amino Acid AntagonistsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2BGlutamate receptor ionotropic, NMDA 2A +2
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Kynurenine DB02070
small molecule | CAS: 2922-83-0

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
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Genetik -
small molecule | CAS: 1758-80-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Envelope glycoprotein gp160
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Genetik -
small molecule | CAS: 73537-09-4

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Cysteine desulfuraseCystathionine gamma-lyase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
S-adenosylmethionine synthase isoform type-1
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Meso-diaminopimelate D-dehydrogenase
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Genetik -
small molecule | CAS: 26630-55-7

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDicarboxylic Acids
Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
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L-377202 DB19022
small molecule | CAS: 207395-85-5

L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).

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L-3972-T DB17441
biotech | CAS: 2170699-22-4

L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.

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L-709,587 DB03621
small molecule

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1A
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L-756423 DB02009
small molecule | CAS: 216863-66-0

Deskripsi belum tersedia.

Kategori:
Antiviral AgentsHIV Protease InhibitorsIndenes
Target Protein:
Gag-Pol polyprotein
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L-778123 DB07227
small molecule | CAS: 183499-57-2

Deskripsi belum tersedia.

Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-1 subunit beta
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L-Acetylleucine Approved DB16956
small molecule | CAS: 1188-21-2

Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo.[A264439] Observational studies in patients with Niemann-Pi…

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +7
Waktu ParuhThe half-life of le…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Kallikrein-7
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Genetik -
small molecule | CAS: 1509-34-8

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins
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Genetik -
small molecule | CAS: 33049-08-0

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Annexin A5
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small molecule | CAS: 1006685-44-4

C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal muscle breakdown. C-101 includes a carnitine carrier mole…

Target Protein:
Calpain-3
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L-Arabinose DB16873
small molecule | CAS: 5328-37-0

Deskripsi belum tersedia.

Kategori:
ArabinoseCarbohydratesMonosaccharides +1
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L-arginine Approved DB17289
small molecule | CAS: 74-79-3

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +3
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L-Baclofen DB12098
small molecule | CAS: 66514-99-6

L-Baclofen has been used in trials studying the treatment of Trigeminal Neuralgia.

Target Protein:
Gamma-aminobutyric acid type B receptor subunit 1
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L-Cycloserine DB17627
small molecule | CAS: 339-72-0

Deskripsi belum tersedia.

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L-cysteic acid DB03661
small molecule | CAS: 498-40-8

L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1
Target Protein:
M-phase inducer phosphatase 2Peptide deformylaseTyrosine-protein phosphatase non-receptor type 1 +13
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small molecule | CAS: 118313-25-0

L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).

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small molecule | CAS: 998-06-1

Deskripsi belum tersedia.

Kategori:
GlycerophosphatesGlycerophospholipidsLipids +3
Target Protein:
Phosphatidylcholine transfer protein
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L-Eflornithine DB03856
small molecule | CAS: 66640-93-5

Deskripsi belum tersedia.

Target Protein:
Ornithine decarboxylase
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small molecule | CAS: 6779-87-9

7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.

Kategori:
CoenzymesEnzymes and CoenzymesHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Nitric oxide synthase, inducibleTyrosine 3-monooxygenasePhenylalanine-4-hydroxylase +3
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L-Gluconic Acid DB04304
small molecule | CAS: 526-97-6

Deskripsi belum tersedia.

Target Protein:
Beta-glucosidase A
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L-Glutamine Approved DB00130
small molecule | CAS: 56-85-9

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cel…

Kategori:
Alimentary Tract and MetabolismAmino AcidsAmino Acids and Derivatives +8
Target Protein:
CTP synthase 1AmidophosphoribosyltransferaseGlutamine synthetase
Waktu ParuhThe half life of el…
Vol. DistribusiVolume of distribut…
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesMonosaccharides
Target Protein:
Ferrichrome-iron receptor
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Genetik -
small molecule | CAS: 25679-93-0

Deskripsi belum tersedia.

Target Protein:
Histidinol-phosphate aminotransferaseHistidinol-phosphate aminotransferase
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L-Homoserine DB04193
small molecule | CAS: 672-15-1

Deskripsi belum tersedia.

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L-Lactic acid Approved DB14475
small molecule | CAS: 79-33-4

Deskripsi belum tersedia.

Kategori:
Hydroxy AcidsLactates
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Genetik -
biotech | CAS: 120484-65-3

Deskripsi belum tersedia.

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small molecule | CAS: 29586-66-1

L-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).

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small molecule | CAS: 62697-73-8

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2
Target Protein:
Thymidylate synthaseAmyloid-beta precursor proteinCatalase +1
Waktu Paruh-
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