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11778

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8554 (72.6%)
Target
6383 (54.2%)
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96 (0.8%)
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11778 (100.0%)

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Halaman 160 / 236
Nattokinase DB15329
biotech | CAS: 133876-92-3

Nattokinase is under investigation in clinical trial NCT00749801 (Efficacy and Safety of Geneferm Nattokinase).

Kategori:
EndopeptidasesEnzymesEnzymes and Coenzymes +5
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Natural Killer (NK) cells originate and differentiate from hematopoietic stem cells through various signalling pathways involving cytokines and interleukins. These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human per…

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NAV 1800 DB05437
biotech

RIGScan CR49, a 125I-labelled CR monoclonal antibody directed against the tumour-associated antigen TAG-72, is undergoing development with Neoprobe for the intraoperative detection of metastatic colorectal cancer.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
Waktu Paruh-
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Navafenterol DB19195
small molecule | CAS: 1435519-06-4

Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).

Kategori:
Heterocyclic Compounds, Fused-Ring
Waktu Paruh-
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Navarixin DB11711
small molecule | CAS: 473727-83-2

Navarixin has been investigated for the treatment of Asthma.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +4
Waktu Paruh-
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Naveglitazar DB12662
small molecule | CAS: 476436-68-7

Naveglitazar has been used in trials studying the treatment of Diabetes Mellitus, Non-Insulin-Dependent.

Kategori:
Acids, CarbocyclicPPAR alpha, agonistsPPAR gamma, agonists
Target Protein:
Peroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alpha
Waktu Paruh-
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Navicixizumab DB12634
biotech | CAS: 1638338-43-8

Navicixizumab is under investigation in clinical trial NCT02298387 (A Phase 1 Study of Navicixizumab in Subjects With Solid Tumors).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
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Navocaftor DB19039
small molecule | CAS: 2159103-66-7

Navocaftor is under investigation in clinical trial NCT04853368 (Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/navocaftor/abbv-119 or Galicaftor/navocaftor/abbv-576 Combination Therapies in Adult Participants…

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Navoximod DB15439
small molecule | CAS: 1402837-78-8

Navoximod is under investigation in clinical trial NCT02048709 (Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors).

Kategori:
Heterocyclic Compounds, Fused-Ring
Waktu Paruh-
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Navuridine DB17759
small molecule | CAS: 84472-85-5

Deskripsi belum tersedia.

Kategori:
DeoxyribonucleosidesDideoxynucleosidesNucleic Acids, Nucleotides, and Nucleosides +3
Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
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Naxifylline DB06471
small molecule | CAS: 166374-49-8

Deskripsi belum tersedia.

Kategori:
Adenosine A1 Receptor AntagonistsAlkaloidsHeterocyclic Compounds, Fused-Ring +6
Target Protein:
Adenosine receptor A1
Waktu Paruh-
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Naxitamab Approved DB15965
biotech | CAS: 1879925-92-4

Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 …

Kategori:
Agents that produce hypertensionAmino Acids, Peptides, and ProteinsAntibodies +18
Target Protein:
GD2 disialoganglioside
Waktu ParuhThe mean terminal h…
Vol. Distribusi-
KlirensThe clearance of na…
Genetik -
Nazartinib DB16250
small molecule | CAS: 1508250-71-2

Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).

Kategori:
AlkaloidsAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Epidermal growth factor receptor
Waktu Paruh-
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NB-001 DB12716
small molecule | CAS: 686301-48-4

NB-001 has been investigated for the treatment of Recurrent Herpes Labialis.

Kategori:
Adenine NucleotidesAdenylyl Cyclase InhibitorsEnzyme Inhibitors +6
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NB-124 sulfate DB16951
small molecule | CAS: 1375073-96-3

Deskripsi belum tersedia.

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NBI-98782 Approved DB16905
small molecule | CAS: 85081-18-1

Deskripsi belum tersedia.

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NC-6300 DB17341
small molecule

NC-6300, also known as K-912, is a novel [epirubicin] drug-conjugated polymeric micelle.

Kategori:
Amino Acids, Peptides, and ProteinsAminoglycoside AntibacterialsAnthracyclines +5
Waktu Paruh-
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NCATS-BL0746 DB18322
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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NCX 1022 DB05410
small molecule | CAS: 571186-50-0

NCX is an NO-releasing derivative of hydrocortisone.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +8
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NCX 701 DB05409
small molecule

Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.

Kategori:
AcetanilidesAmidesAmines +6
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
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ND7001 DB05142
small molecule

ND7001, a selective PDE2 inhibitor is in clinical trials for the treatment of depression. ND7001 is a solid. Known drug targets of ND7001 including phosphodiesterase 2A, cGMP-stimulated and cGMP-dependent 3',5'-cyclic phosphodiesterase. It is a new type of an…

Target Protein:
cGMP-dependent 3',5'-cyclic phosphodiesterase
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NDI-5001 DB17609
small molecule | CAS: 1365571-66-9

Deskripsi belum tersedia.

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NDX-3315 DB18671
small molecule

NDX-3315 is an investigational radiopharmaceutical agent for the diagnosis, treatment monitoring, and management of eosinophilic esophagitis. It is a technetium-99m radiolabeled [heparin].

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Neamine DB04808
small molecule | CAS: 3947-65-7

Deskripsi belum tersedia.

Kategori:
Agents that produce neuromuscular block (indirect)Aminoglycoside AntibacterialsAnti-Bacterial Agents +3
Waktu Paruh-
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Nebicapone DB14849
small molecule | CAS: 274925-86-9

Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-do…

Kategori:
COMT InhibitorsKetones
Target Protein:
Catechol O-methyltransferase
Waktu Paruh-
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Nebivolol Approved DB04861
small molecule | CAS: 118457-14-0

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity.[A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic Antagonists +29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorBeta-3 adrenergic receptor
Waktu Paruhd-nebivolol has a h…
Vol. DistribusiFor a 20mg dose, d-…
KlirensFor a 20mg dose, th…
Genetik -
Nedaplatin Approved DB13145
small molecule | CAS: 95734-82-0

Nedaplatin is a second generation platinum analog [A20300]. It is less nephrotoxic than [DB00515] but has proven equally effective. It was approved for use in Japan in 1995.

Kategori:
Antineoplastic AgentsDrugs that are Mainly Renally ExcretedDrugs that are Mainly Renally Excreted with a Narrow Therapeutic Index +3
Target Protein:
DNAGlutathione
Waktu Paruh-
Vol. DistribusiThe volume of distr…
KlirensClearance of the fr…
Genetik -
Nedisertib DB16252
small molecule | CAS: 1637542-33-6

Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingProtein Kinase Inhibitors
Target Protein:
DNA-dependent protein kinase catalytic subunit
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Nedocromil Approved DB00716
small molecule | CAS: 69049-73-6

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.

Kategori:
4-QuinolonesAnti-Allergic AgentsAnti-Asthmatic Agents +16
Target Protein:
Cysteinyl leukotriene receptor 1Cysteinyl leukotriene receptor 2fMet-Leu-Phe receptor +2
Waktu Paruh~3.3 hours
Vol. Distribusi-
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Nedosiran Approved DB17635
biotech | CAS: 2266591-83-5

Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate.[A261690] Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore…

Target Protein:
L-lactate dehydrogenase A chain
Waktu ParuhThe half-life of ne…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of ne…
Genetik -
Nefiracetam DB13082
small molecule | CAS: 77191-36-7

Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
Central Nervous System AgentsCentral Nervous System DepressantsCompounds used in a research, industrial, or household setting +5
Waktu Paruh-
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Neflamapimod DB07138
small molecule | CAS: 209410-46-8

Neflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.

Target Protein:
Mitogen-activated protein kinase 11Mitogen-activated protein kinase 12Mitogen-activated protein kinase 14
Waktu Paruh-
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Nefopam Approved DB12293
small molecule | CAS: 13669-70-0

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.

Kategori:
AnalgesicsAnalgesics, Non-NarcoticAzocines +5
Waktu Paruh-
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biotech

Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
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biotech

Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria meningitidis* serogroup a. The vaccine contains *N. m…

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
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Genetik -
biotech

Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria meningitidis* serogroup c. The vaccine contains *N. m…

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
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Genetik -
biotech

Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
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Genetik -
biotech

Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

Kategori:
Actively Acquired ImmunityInactivated Meningococcal Vaccine
Waktu Paruh-
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Genetik -
biotech

Deskripsi belum tersedia.

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biotech

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biotech

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biotech

Deskripsi belum tersedia.

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Nelarabine Approved DB01280
small molecule | CAS: 121032-29-9

Nelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), in both adult and pediatric patients whose disease h…

Kategori:
AntimetabolitesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +8
Target Protein:
DNADNA polymerase alpha catalytic subunitDNA ligase 1 +2
Waktu ParuhNelarabine and ara-…
Vol. DistribusiNelarabine and ara-…
KlirensRenal clearance ave…
Genetik -
Nelatimotide DB17249
small molecule | CAS: 1629213-88-2

Deskripsi belum tersedia.

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Nelfinavir Approved DB00220
small molecule | CAS: 159989-64-7

Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, …

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +45
Target Protein:
HIV-1 protease
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe apparent volume…
KlirensOral clearance esti…
Genetik -
Nelipepimut-S DB06226
biotech | CAS: 160212-35-1

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntigensAntigens, Surface +25
Target Protein:
Receptor tyrosine-protein kinase erbB-2HLA class I histocompatibility antigen, A-3 alpha chain
Waktu Paruh-
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Nelistotug DB19334
biotech | CAS: 2645437-82-5

Nelistotug is under investigation in clinical trial NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-2…

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Nelivaptan DB12643
small molecule | CAS: 439687-69-1

Nelivaptan has been used in trials studying the treatment of Anxiety Disorders, Depressive Disorder, and Major Depressive Disorder.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Vasopressin V1b receptorVasopressin V2 receptorOxytocin receptor +1
Waktu Paruh-
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Nelonicline DB19040
small molecule | CAS: 1026134-63-3

Nelonicline is under investigation in clinical trial NCT01678755 (A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia).

Kategori:
Sulfur CompoundsThiazoles
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