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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 160 / 282
JAB-21822 DB17478
small molecule

JAB-21822 is an oral small-molecule KRAS G12C inhibitor.

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JAG101 DB18321
biotech

Deskripsi belum tersedia.

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JAK4D DB18527
small molecule | CAS: 882400-49-9

JAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.

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Jaktinib DB17545
small molecule

Jaktinib is a JAK 1, JAK 2 and JAK 3 inhibitor, being developed by Suzhou Zelgen Biopharmaceuticals. Jaktinib is under investigation in clinical trial NCT04866056 (Jaktinib and Azacitidine in Treating Patients With MDS With MF or MDS/MPN With MF.).

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Janagliflozin DB16209
small molecule | CAS: 1800115-22-3

Janagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin).

Kategori:
AlcoholsCarbohydratesCyclohexanes +2
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Janssen COVID-19 Vaccine Approved DB15857
biotech

The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharma…

Kategori:
Biological ProductsComplex MixturesCOVID-19 Vaccines +2
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biotech

Deskripsi belum tersedia.

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biotech

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Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +3
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biotech

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Kategori:
Inactivated Japanese Encephalitis Virus Vaccine
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JBI-802 DB17399
small molecule

Deskripsi belum tersedia.

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JCAR014 DB17232
biotech

Deskripsi belum tersedia.

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JE-2147 DB02668
small molecule | CAS: 186538-00-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmino Acids, Peptides, and ProteinsAntiviral Agents +4
Target Protein:
Gag-Pol polyproteinGag-Pol polyprotein
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JHU-75528 C-11 DB14902
small molecule | CAS: 942063-86-7

JHU-75528 C-11 is under investigation in clinical trial NCT03204305 (Brain Imaging of Cannabinoid Receptors).

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JLK-247 DB17637
biotech

JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.[L46686]

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JNJ-17216498 DB17087
small molecule | CAS: 1035626-05-1

JNJ-17216498 is a histamine receptor H3 antagonist developed by Johnson and Johnson for the treatment of narcolepsy.[A253997]

Target Protein:
Histamine H3 receptor
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JNJ-1802 DB17734
small molecule | CAS: 2043343-94-6

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
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JNJ-26489112 DB15203
small molecule | CAS: 871824-55-4

JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy).

Kategori:
AmidesAnticonvulsantsCentral Nervous System Depressants +2
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JNJ-27390467 DB06962
small molecule | CAS: 1025795-11-2

JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.

Target Protein:
Tryptase beta-2
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JNJ-27548547 DB15372
small molecule | CAS: 303983-00-8

JNJ-27548547 is under investigation in clinical trial NCT01705002 (Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.).

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JNJ-28312141 DB17140
small molecule | CAS: 885692-52-4

Deskripsi belum tersedia.

Kategori:
Receptors, Colony-Stimulating Factor, antagonists & inhibitors
Target Protein:
NT-3 growth factor receptorMast/stem cell growth factor receptor KitTyrosine-protein kinase Lck +1
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JNJ-28330835 DB13936
small molecule | CAS: 888072-47-7

A selective androgen receptor modulator with minimal prostate hypertrophic activity, enhances lean body mass in male rats and stimulates sexual behavior in female rats.

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JNJ-37822681 DB12579
small molecule | CAS: 935776-74-2

JNJ-37822681 has been used in trials studying the treatment of Schizophrenia.

Kategori:
Dopamine AgentsDopamine AntagonistsDopamine D2 Receptor Antagonists +1
Target Protein:
D(2) dopamine receptor
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JNJ-39220675 DB12929
small molecule | CAS: 959740-39-7

JNJ-39220675 has been used in trials studying the treatment of Allergic Rhinitis.

Kategori:
Histamine H3 Antagonists
Target Protein:
Histamine H3 receptor
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JNJ-39393406 DB11867
small molecule | CAS: 953428-73-4

JNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.

Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
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JNJ-39758979 DB18899
small molecule | CAS: 1046447-90-8

JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).

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JNJ-40346527 DB12504
small molecule | CAS: 1142363-52-7

JNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.

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JNJ-40411813 DB12059
small molecule | CAS: 1127498-03-6

JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.

Kategori:
Pyridines
Target Protein:
Metabotropic glutamate receptor 2
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JNJ-41443532 DB12632
small molecule | CAS: 1228650-83-6

JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.

Kategori:
Acids, CarbocyclicAmidesAzetines +2
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JNJ-42165279 DB15173
small molecule | CAS: 1346528-50-4

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).

Kategori:
Enzyme Inhibitors
Target Protein:
Fatty-acid amide hydrolase 1
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JNJ-42396302 DB12657
small molecule | CAS: 1298030-18-8

Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).

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JNJ-54175446 DB15358
small molecule | CAS: 1627902-21-9

JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid and Plasma).

Target Protein:
P2X purinoceptor 7
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JNJ-55308942 DB19110
small molecule | CAS: 2166558-11-6

JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

Kategori:
Neurotransmitter AgentsPurinergic AgentsPurinergic Antagonists +2
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JNJ-75276617 DB17574
small molecule

JNJ-75276617 is under investigation in clinical trial NCT05453903 (A Study of JNJ-75276617 in Combination With Acute Myeloid Leukemia (AML) Directed Therapies).

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JNT-517 DB19305
small molecule | CAS: 2837993-05-0

Deskripsi belum tersedia.

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Jojoba oil Approved DB14252
biotech | CAS: 61789-91-1

Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsCosmeticsLipids +3
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Josamycin DB01321
small molecule | CAS: 16846-24-5

A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +5
Target Protein:
50S ribosomal protein L4
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small molecule | CAS: 40922-77-8

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsLactonesMacrolides +1
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JPC-3210 DB15609
small molecule | CAS: 1609655-35-7

JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant _Plasmodium falciparum_ lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable…

Kategori:
AntimalarialsAntiviral AgentsBenzene Derivatives
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JQ1 DB17021
small molecule | CAS: 1268524-70-4

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

Target Protein:
Bromodomain-containing protein 4Bromodomain testis-specific protein
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JS-K DB17257
small molecule | CAS: 205432-12-8

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JSM 6427 DB06139
small molecule

JSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed. It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age…

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small molecule | CAS: 244218-93-7

An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.[A253027]

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
Nociceptin receptor
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JTT-251 DB18174
small molecule | CAS: 1627957-25-8

Deskripsi belum tersedia.

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Juniperus monosperma pollen Approved DB10727
biotech

Juniperus monosperma pollen is the pollen of the Juniperus monosperma plant. Juniperus monosperma pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus pinchotii pollen Approved DB10728
biotech

Juniperus pinchotii pollen is the pollen of the Juniperus pinchotii plant. Juniperus pinchotii pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Juniperus scopulorum pollen Approved DB10729
biotech

Juniperus scopulorum pollen is the pollen of the Juniperus scopulorum plant. Juniperus scopulorum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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small molecule

JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.

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K-00546 DB07664
small molecule | CAS: 443798-47-8

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 1Cyclin-dependent kinase 1Cyclin-dependent kinase 2 +5
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K-134 DB12685
small molecule | CAS: 189362-06-9

K-134 has been used in trials studying the treatment of Intermittent Claudication.

Kategori:
AmidesHeterocyclic Compounds, Fused-Ring
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K-252a DB02152
small molecule | CAS: 97161-97-2

Deskripsi belum tersedia.

Kategori:
AlkaloidsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Dual specificity mitogen-activated protein kinase kinase 1Hepatocyte growth factor receptor
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