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KT-253 DB18487

small molecule

KT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).

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KT-333 DB17165

small molecule

KT-333 is a small molecule targeted protein degrader of STAT3.[L44086]

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KT-A261 DB19317

biotech

KT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.

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KTH-222 DB17314

biotech

Deskripsi belum tersedia.

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KTX-1001 DB18171

small molecule

Deskripsi belum tersedia.

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KUR-113 DB18413

biotech

KUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.

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KUS-121 free acid DB18510

small molecule | CAS: 1357245-09-0

Deskripsi belum tersedia.

Kategori:

AcidsAcids, NoncarboxylicSulfur Acids +1

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KW-2450 free base DB16637

small molecule | CAS: 904899-25-8

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingPyrazoles

Target Protein:

Insulin receptorInsulin-like growth factor 1 receptor

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KW-6356 DB17080

small molecule

KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

Target Protein:

Adenosine receptor A2a

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KX-2361 DB17180

small molecule | CAS: 897016-26-1

Deskripsi belum tersedia.

Kategori:

AcetatesAcids, AcyclicAmides +6

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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Kynurenic Acid DB11937

small molecule | CAS: 492-27-3

Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).

Kategori:

Excitatory Amino Acid AgentsExcitatory Amino Acid AntagonistsHeterocyclic Compounds, Fused-Ring +4

Target Protein:

Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2BGlutamate receptor ionotropic, NMDA 2A +2

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Kynurenine DB02070

small molecule | CAS: 2922-83-0

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Peptides, and Proteins

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L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid DB08693

small molecule

Deskripsi belum tersedia.

Target Protein:

Chymotrypsinogen B

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L-2,4-diaminobutyric acid DB03817

small molecule | CAS: 1758-80-1

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1

Target Protein:

Envelope glycoprotein gp160

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L-2-amino-3-butynoic acid DB04217

small molecule | CAS: 73537-09-4

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1

Target Protein:

Cysteine desulfuraseCystathionine gamma-lyase

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L-2-amino-4-methoxy-cis-but-3-enoic acid DB03611

small molecule

Deskripsi belum tersedia.

Target Protein:

S-adenosylmethionine synthase isoform type-1

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L-2-aminopimelic acid DB03134

small molecule | CAS: 26630-55-7

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicDicarboxylic Acids

Target Protein:

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

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L-377202 DB19022

small molecule | CAS: 207395-85-5

L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).

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L-3972-T DB17441

biotech | CAS: 2170699-22-4

L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.

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L-709,587 DB03621

small molecule

Deskripsi belum tersedia.

Target Protein:

Peptidyl-prolyl cis-trans isomerase FKBP1A

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L-756423 DB02009

small molecule | CAS: 216863-66-0

Deskripsi belum tersedia.

Kategori:

Antiviral AgentsHIV Protease InhibitorsIndenes

Target Protein:

Gag-Pol polyprotein

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L-778123 DB07227

small molecule | CAS: 183499-57-2

Deskripsi belum tersedia.

Target Protein:

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-1 subunit beta

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L-Acetylleucine Approved DB16956

small molecule | CAS: 1188-21-2

Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo.[A264439] Observational studies in patients with Niemann-Pi…

Kategori:

Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +7

Waktu ParuhThe half-life of le…

Vol. DistribusiThe apparent volume…

KlirensThe apparent oral c…

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L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide DB08038

small molecule

Deskripsi belum tersedia.

Target Protein:

Kallikrein-7

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L-alloisoleucine DB01739

small molecule | CAS: 1509-34-8

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins

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L-alpha-Glycerophosphorylethanolamine DB15872

small molecule | CAS: 33049-08-0

Deskripsi belum tersedia.

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L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine DB03047

small molecule

Deskripsi belum tersedia.

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L-Arabinose DB16873

small molecule | CAS: 5328-37-0

Deskripsi belum tersedia.

Kategori:

ArabinoseCarbohydratesMonosaccharides +1

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L-arginine Approved DB17289

small molecule | CAS: 74-79-3

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, BasicAmino Acids, Diamino +3

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L-Cycloserine DB17627

small molecule | CAS: 339-72-0

Deskripsi belum tersedia.

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L-cysteic acid DB03661

small molecule | CAS: 498-40-8

L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light…

Kategori:

Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1

Target Protein:

M-phase inducer phosphatase 2Peptide deformylaseTyrosine-protein phosphatase non-receptor type 1 +13

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L-deprenyl-D2 C-11 DB12650

small molecule | CAS: 118313-25-0

L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).

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L-Dilinoleoyllecithin DB04372

small molecule | CAS: 998-06-1

Deskripsi belum tersedia.

Kategori:

GlycerophosphatesGlycerophospholipidsLipids +3

Target Protein:

Phosphatidylcholine transfer protein

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L-Eflornithine DB03856

small molecule | CAS: 66640-93-5

Deskripsi belum tersedia.

Target Protein:

Ornithine decarboxylase

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L-gamma-glutamyl-S-(naphthalen-1-ylmethyl)-L-cysteinylglycine DB03885

small molecule

Deskripsi belum tersedia.

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L-Gluconic Acid DB04304

small molecule | CAS: 526-97-6

Deskripsi belum tersedia.

Target Protein:

Beta-glucosidase A

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L-Glutamine Approved DB00130

small molecule | CAS: 56-85-9

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cel…

Kategori:

Alimentary Tract and MetabolismAmino AcidsAmino Acids and Derivatives +8

Target Protein:

CTP synthase 1AmidophosphoribosyltransferaseGlutamine synthetase

Waktu ParuhThe half life of el…

Vol. DistribusiVolume of distribut…

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L-Histidine Beta Naphthylamide DB01938

small molecule

Deskripsi belum tersedia.

Target Protein:

Hut operon positive regulatory protein

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L-histidinol phosphate DB03997

small molecule | CAS: 25679-93-0

Deskripsi belum tersedia.

Target Protein:

Histidinol-phosphate aminotransferaseHistidinol-phosphate aminotransferase

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L-homoarginine DB03974

small molecule | CAS: 156-86-5

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, BasicAmino Acids, Diamino +2

Target Protein:

Nitric oxide synthase 3

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L-Homoserine DB04193

small molecule | CAS: 672-15-1

Deskripsi belum tersedia.

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L-Lactic acid Approved DB14475

small molecule | CAS: 79-33-4

Deskripsi belum tersedia.

Kategori:

Hydroxy AcidsLactates

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L-Leucyl-Hydroxylamine DB03308

small molecule

Deskripsi belum tersedia.

Target Protein:

Thermolysin

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L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine DB17176

biotech | CAS: 120484-65-3

Deskripsi belum tersedia.

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L-lysyl-l-arginine DB19436

small molecule | CAS: 29586-66-1

L-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).

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L-methionine (R)-S-oxide DB02235

small molecule | CAS: 62697-73-8

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2

Target Protein:

Thymidylate synthaseAmyloid-beta precursor proteinCatalase +1

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L-methionine sulfone DB03790

small molecule | CAS: 7314-32-1

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2

Target Protein:

Catalase

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L-Myo-Inositol-1-Phosphate DB03542

small molecule

Deskripsi belum tersedia.

Target Protein:

Inositol monophosphatase 1

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L-naphthyl-1-acetamido boronic acid alanine DB03290

small molecule

Deskripsi belum tersedia.

Target Protein:

Subtilisin Carlsberg

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L-Octahydroindole-2-carboxylic acid DB03409

small molecule | CAS: 80875-98-5

Deskripsi belum tersedia.

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