Hasil Filter

15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (15718)

Halaman 154 / 315
Hippuric acid DB16842
small molecule | CAS: 495-69-2

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hispidulin DB14008
small molecule | CAS: 1447-88-7

Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties [A32513].

Kategori:
BenzopyransChromonesFlavonoids +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histamine Approved DB05381
small molecule | CAS: 51-45-6

A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Kategori:
Adjuvants, ImmunologicAminesAntineoplastic and Immunomodulating Agents +19
Target Protein:
Histamine H1 receptorHistamine H2 receptorHistamine H3 receptor +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1464897-15-1

Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).

Kategori:
AminesAnti-Asthmatic AgentsAutacoids +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histapyrrodine DB13479
small molecule | CAS: 493-80-1

Deskripsi belum tersedia.

Kategori:
Antihistamines for Systemic UseSubstituted Ethylene Diamines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histidine DB00117
small molecule | CAS: 71-00-1

An essential amino acid that is required for the production of histamine.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Essential +4
Target Protein:
Histidine decarboxylaseHistidine--tRNA ligase, cytoplasmicSodium-coupled neutral amino acid transporter 3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histidinol DB03811
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +3
Target Protein:
Histidinol dehydrogenaseHistidine--tRNA ligase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Histidine--tRNA ligaseHistidine--tRNA ligase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histrelin Approved DB06788
small molecule | CAS: 76712-82-8

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher pot…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +17
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe apparent volume…
KlirensIn prostate cancer …
Genetik -
small molecule | CAS: 729607-74-3

HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HKI-357 DB13002
small molecule | CAS: 848133-17-5

Hki 357 is under investigation in clinical trial NCT00550381 (Study Evaluating the Safety, Tolerability, and Pharmacokinetics (PK) of HKI-357 Administered Orally to Healthy Subjects).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HL001 DB18026
small molecule | CAS: 1186371-31-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HLX-58 DB18699
biotech

HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HLX70 DB16509
biotech

HLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics in healthy adult volunteers. The condition …

Kategori:
Experimental Unapproved Treatments for COVID-19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HM-30181 DB14070
small molecule | CAS: 849675-66-7

Deskripsi belum tersedia.

Kategori:
ATP Binding Cassette Transporter, Subfamily B, Member 1, antagonists & inhibitorsHeterocyclic Compounds, Fused-RingP-glycoprotein inhibitors +1
Target Protein:
ATP-dependent translocase ABCB1Phosphatidylcholine translocator ABCB4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HM15912 DB18266
biotech

HM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HMI-103 DB17684
biotech

HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HMI-203 DB18520
biotech

HMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HMI-204 DB18338
biotech

HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HMR4011 DB06225
small molecule

HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. IPL 576,092 has previously been investigated as a treatment for asthma.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HNM01 DB06531
biotech

The drug hNM01, a humanized monoclonal antibody developed by SRD Pharmaceuticals, Inc., targets the V(3) region of the HIV-1 envelope protein gp120, functioning as an HIV replication inhibitor. It entered Phase 1 clinical trials for the treatment of HIV infec…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Holcus lanatus pollen Approved DB10395
biotech

Holcus lanatus pollen is the pollen of the Holcus lanatus plant. Holcus lanatus pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityGrass Pollen Allergen ExtractsIncreased Histamine Release +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homatropine Approved DB11181
small molecule | CAS: 87-00-3

Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic r…

Kategori:
AlkaloidsAnticholinergic AgentsAutonomic Agents +8
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Homatropine methylbromide Approved DB00725
small molecule | CAS: 80-49-9

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAlkaloids +7
Target Protein:
Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M4 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homidium DB17031
small molecule | CAS: 3546-21-2

Homidium is a group II compound with trypanocidal effects.[A253017]

Kategori:
Anti-Infective AgentsAnticholinergic AgentsAntiparasitic Agents +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 848-53-3

Deskripsi belum tersedia.

Kategori:
Piperazines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homocysteine DB04422
small molecule | CAS: 6027-13-0

Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1
Target Protein:
S-ribosylhomocysteine lyase5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase5-methyltetrahydrofolate S-homocysteine methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 451-13-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicPhenylacetates
Target Protein:
Penicillin G acylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin F
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homosalate Approved DB11064
small molecule | CAS: 118-56-9

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet…

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Target Protein:
Progesterone receptorAndrogen receptorEstrogen receptor
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
small molecule | CAS: 1192-20-7

Deskripsi belum tersedia.

Kategori:
FuransLactonesLuminescent Proteins
Target Protein:
Sodium/hydrogen exchanger 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Honey Approved DB14242
biotech | CAS: 8028-66-8

Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Honeydew melon Approved DB10536
biotech

Honeydew melon allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Honokiol DB19283
small molecule | CAS: 35354-74-6

Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).

Kategori:
AlkenesAnti-Allergic AgentsAnti-Anxiety Agents +24
Target Protein:
Polyunsaturated fatty acid 5-lipoxygenaseProstaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hopantenic acid DB14044
small molecule | CAS: 18679-90-8

Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115]

Kategori:
Acids, AcyclicAlanineAmino Acids +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hops Approved DB10687
biotech

Hops allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityHerbs and Natural ProductsIncreased Histamine Release +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hordeum vulgare pollen Approved DB10961
biotech

Hordeum vulgare pollen is the pollen of the Hordeum vulgare plant. Hordeum vulgare pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Horse chestnut DB13195
biotech

Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are pro…

Kategori:
AngiospermsBiological ProductsCapillary Stabilizing Agents +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Horseradish Approved DB10674
biotech

Horseradish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
House dust Approved DB10345
biotech

House dust allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityComplex MixturesIncreased Histamine Release +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HOV-12020 DB17976
small molecule

HOV-12020 is a palm tocotrienols complex being investigated for the treatment of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).[L47271]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HPA-23 DB17739
small molecule | CAS: 89899-81-0

HPA-23 is an investigational antiviral compound.[A259142]

Kategori:
Anti-Infective AgentsAntineoplastic AgentsAntiviral Agents +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HQP1351 DB16185
small molecule | CAS: 1257628-77-5

HQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HRS-1167 DB18703
small molecule

HRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HSD-016 DB12419
small molecule | CAS: 946396-92-5

Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

Kategori:
Alcohols
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HSK-3486 DB16295
small molecule | CAS: 1637741-58-2

HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).

Kategori:
Benzene Derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HSV-2 theracine DB05811
biotech

HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HT-0712 DB11650
small molecule | CAS: 617720-02-2

BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).

Kategori:
Piperidines
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HT-KIT DB18467
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 7651–7700 dari 15718
Sebelumnya Halaman 154 / 315 Berikutnya