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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (17430)

Halaman 150 / 349
small molecule | CAS: 686723-15-9

Deskripsi belum tersedia.

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small molecule | CAS: 548-00-5

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

Kategori:
4-HydroxycoumarinsAnticoagulantsBenzopyrans +9
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Ethyl butyrate DB15454
small molecule | CAS: 105-54-4

Ethyl butyrate is under investigation in clinical trial NCT03202342 (fMRI of Hypothalamic Responses to Taste, Temperature and Glucose).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
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Ethyl chloride Approved DB13259
small molecule | CAS: 75-00-3

Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the…

Kategori:
AnestheticsAnesthetics, LocalCentral Nervous System Agents +6
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small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 1623-14-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +7
Target Protein:
CholinesteraseParathion hydrolase
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small molecule

Deskripsi belum tersedia.

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Ethyl ferulate Approved DB11285
small molecule | CAS: 4046-02-0

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicCinnamates
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small molecule

Deskripsi belum tersedia.

Kategori:
Cholinesterase Inhibitors
Target Protein:
Cholinesterase
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Ethyl hydroxybenzoate Approved DB13628
small molecule | CAS: 120-47-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAntifungals for Dermatological UseAntifungals for Topical Use +9
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Myoglobin
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small molecule | CAS: 29177-84-2

Deskripsi belum tersedia.

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepines and benzodiazepine derivatives +7
Target Protein:
GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
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Ethyl macadamiate Approved DB11243
small molecule

Ethyl macadamiate is derived from Macadamia terifolia seed oil. It is a non-volatile ester of ethyl alcohol and the fatty acids. Ethyl macadamiate is used in cosmetics and personal care products such as sunscreen, hair care products and skin care products as …

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small molecule | CAS: 24393-56-4

Deskripsi belum tersedia.

Kategori:
Sunscreen Agents
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small molecule | CAS: 105-40-8

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCarbamates
Target Protein:
Shiga-like toxin 1 subunit B
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Ethyl nitrite DB16560
small molecule | CAS: 109-95-5

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIons +1
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small molecule | CAS: 53074-96-7

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase A
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small molecule | CAS: 41653-21-8

Deskripsi belum tersedia.

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Ethyl pyruvate DB05869
small molecule | CAS: 617-35-6

CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-rep…

Kategori:
Keto Acids
Target Protein:
Tumor necrosis factorHigh mobility group protein B1
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Ethyl salicylate Approved DB15576
small molecule | CAS: 118-61-6

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +3
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Shiga-like toxin 1 subunit B
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small molecule | CAS: 3439-38-1

Deskripsi belum tersedia.

Target Protein:
Tetanus toxin
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small molecule

Deskripsi belum tersedia.

Target Protein:
Candidapepsin-2
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small molecule | CAS: 107-06-2

Deskripsi belum tersedia.

Kategori:
AlkanesEthaneHydrocarbons, Acyclic +2
Target Protein:
Haloalkane dehalogenase
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Ethylenediamine Approved DB14189
small molecule | CAS: 107-15-3

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer c…

Kategori:
AllergensAminesAntigens +6
Target Protein:
Dihydropteroate synthase
Waktu ParuhEthylenediamine has…
Vol. DistribusiVd = 0.133 l/kg [A3…
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Ethylestrenol DB01493
small molecule | CAS: 965-90-2

An anabolic steroid with some progestational activity and little androgenic effect. [PubChem]

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +9
Target Protein:
Androgen receptor
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Ethylhexyl methoxycrylene Approved DB11226
small molecule | CAS: 947753-66-4

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states [F104]. It returns UV filters to their ground states without absorbing sunlight [F104]. It is used as a solve…

Waktu ParuhEthylhexyl methoxyc…
Vol. DistribusiEthylhexyl methoxyc…
KlirensEthylhexyl methoxyc…
Genetik -
small molecule | CAS: 70445-33-9

An emollient solvent with antimicrobial activity.

Kategori:
AlcoholsEthersSugar Alcohols +1
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small molecule | CAS: 148-61-8

Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.

Target Protein:
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialSensor histidine kinase
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small molecule | CAS: 441-61-2

Deskripsi belum tersedia.

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Ethylmorphine DB01466
small molecule | CAS: 76-58-4

A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a sched…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +22
Target Protein:
Mu-type opioid receptor
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Ethynodiol diacetate Approved DB00823
small molecule | CAS: 297-76-7

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacet…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +19
Target Protein:
Progesterone receptorEstrogen receptor
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Eticlopride DB15492
small molecule | CAS: 84226-12-0

Deskripsi belum tersedia.

Kategori:
AmidesDopamine AgentsDopamine Antagonists +1
Target Protein:
D(2) dopamine receptor
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Etidocaine Approved DB08987
small molecule | CAS: 36637-18-0

Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

Kategori:
AcetanilidesAmidesAmines +10
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Etidronic acid Approved DB01077
small molecule | CAS: 2809-21-4

Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.[A1923] Etidronate’s use has decr…

Kategori:
BisphosphonatesBone Density Conservation AgentsDrugs Affecting Bone Structure and Mineralization +4
Target Protein:
HydroxylapatiteReceptor-type tyrosine-protein phosphatase SV-type proton ATPase catalytic subunit A +3
Waktu ParuhThe half life of et…
Vol. DistribusiEtidronic acid has …
KlirensEtidronic acid has …
Genetik -
Etifoxine DB08986
small molecule | CAS: 21715-46-8

Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiaze…

Kategori:
Anti-Anxiety AgentsCentral Nervous System AgentsCentral Nervous System Depressants +4
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Etigilimab DB18854
biotech | CAS: 2044984-83-8

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

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Etilamfetamine DB13285
small molecule | CAS: 457-87-4

Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this amphetamine analog was used as an appetite suppressant in the 1…

Kategori:
Alimentary Tract and MetabolismAntiobesity Preparations, Excl. Diet ProductsCentrally Acting Antiobesity Products
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Etilefrine Approved DB08985
small molecule | CAS: 709-55-7

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-Agonists +20
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Etilevodopa DB06535
small molecule | CAS: 37178-37-3

Deskripsi belum tersedia.

Kategori:
AminesAmino AcidsAmino Acids, Aromatic +11
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small molecule | CAS: 1229-12-5

Deskripsi belum tersedia.

Target Protein:
Immunoglobulin heavy constant gamma 2Immunoglobulin heavy constant gamma 1Immunoglobulin kappa constant +1
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small molecule | CAS: 199331-40-3

Etiprednol dicloacetate (BNP-166) is a soft corticosteroid with anti-inflammatory properties that has been indicated in the treatment of asthma and Chron's disease. Anti-asthmatic effects were associated with decreased cytokine production in lipopolysaccharid…

Kategori:
HormonesHormones, Hormone Substitutes, and Hormone Antagonists
Target Protein:
Glucocorticoid receptorInterleukin-1 beta
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Etiracetam DB11868
small molecule | CAS: 33996-58-6

Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).

Kategori:
AcetamidesAcetatesAcids, Acyclic +7
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small molecule | CAS: 848779-32-8

Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).

Kategori:
AlcoholsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +9
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Etizolam DB09166
small molecule | CAS: 40054-69-1

Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant,…

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepine hypnotics and sedatives +17
Target Protein:
GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding SitePlatelet-activating factor receptor
Waktu ParuhThe average elimina…
Vol. DistribusiApparent distributi…
Klirens-
Genetik -
Etodolac Approved DB00749
small molecule | CAS: 41340-25-4

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rhe…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +29
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1Retinoic acid receptor RXR-alpha
Waktu ParuhTerminal t<sub>1/2<…
Vol. Distribusi* 390 mL/kg
Klirens* Oral cl=49.1 mL/h…
Genetik -
Etofamide Approved DB13258
small molecule | CAS: 25287-60-9

Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].

Kategori:
AcetatesAcids, AcyclicAmebicides +6
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Etofenamate DB08984
small molecule | CAS: 30544-47-9

Etofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +18
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Etofibrate DB08983
small molecule | CAS: 31637-97-5

Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.

Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityAnticholesteremic Agents +11
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small molecule | CAS: 13425-39-3

Etofylline nicotinate, a theophylline derivative, is a drug that causes vasodilation and relaxation of smooth muscle.

Kategori:
Peripheral VasodilatorsPurine Derivatives
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