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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (14063)

Halaman 149 / 282
Indian frankincense Approved DB14275
biotech

Indian frankincense is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indibulin DB06169
small molecule | CAS: 204205-90-3

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indigo DB16862
small molecule | CAS: 482-89-3

Deskripsi belum tersedia.

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Aryl hydrocarbon receptor
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Indigotindisulfonic acid Approved DB11577
small molecule | CAS: 483-20-5

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in …

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingDiagnostic Agents +5
Target Protein:
Alpha adrenergic receptor
Waktu ParuhIn healthy adults g…
Vol. DistribusiThe volume of distr…
KlirensIn healthy adults g…
Genetik -
Indinavir Approved DB00224
small molecule | CAS: 150378-17-9

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +33
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh1.8 (± 0.4) …
Vol. Distribusi-
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Genetik -
Indiplon DB12590
small molecule | CAS: 325715-02-4

Indiplon has been used in trials studying the treatment of Insomnia and Depression.

Kategori:
BenzazepinesCentral Nervous System AgentsCentral Nervous System Depressants +7
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1
Waktu Paruh-
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Indirubin DB12379
small molecule | CAS: 479-41-4

Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).

Kategori:
Antibiotics, AntineoplasticAntineoplastic AgentsColoring Agents +4
Target Protein:
Cytochrome P450 1A1Aryl hydrocarbon receptor
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AminesHeterocyclic Compounds, Fused-RingHydroxylamines
Target Protein:
Cyclin-dependent kinase 5 activator 1Cyclin-dependent kinase 2Aryl hydrocarbon receptor +3
Waktu Paruh-
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small molecule | CAS: 244021-67-8

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle formCell division control protein 2 homolog
Waktu Paruh-
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Indium In-111 DB11916
small molecule | CAS: 15750-15-9

Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).

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Genetik -
biotech | CAS: 156586-92-4

Deskripsi belum tersedia.

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Indium In-111 pentetate Approved DB09425
small molecule | CAS: 135998-32-2

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.

Kategori:
Central Nervous SystemDiagnostic RadiopharmaceuticalsRadioactive Diagnostic Agent +1
Waktu ParuhIndium 111 decays b…
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biotech | CAS: 138955-27-8

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.

Kategori:
AcetatesAcids, AcyclicAmines +14
Target Protein:
Tumor-associated glycoprotein 72 (TAG-72)
Waktu Paruh0.8 hours (mammalia…
Vol. Distribusi-
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Genetik -
Indobufen DB12545
small molecule | CAS: 63610-08-2

Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16
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Indocyanine green Approved DB16024
small molecule | CAS: 3599-32-4

Deskripsi belum tersedia.

Kategori:
Cardiac FunctionColoring AgentsCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
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Indocyanine green acid form Approved DB09374
small molecule | CAS: 28782-33-4

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl…

Kategori:
BSEP/ABCB11 SubstratesCardiac FunctionColoring Agents +6
Waktu ParuhICG has a half-life…
Vol. DistribusiICG distribution in…
KlirensClearance of dyes w…
Genetik -
Indole DB04532
small molecule | CAS: 120-72-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
EndolysinNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
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small molecule | CAS: 700-06-1

Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsCompounds used in a research, industrial, or household setting +2
Target Protein:
NF-kappa-B inhibitor alpha
Waktu Paruh-
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Indoleacetamide DB08652
small molecule | CAS: 879-37-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Target Protein:
Aralkylamine dehydrogenase light chainAralkylamine dehydrogenase heavy chain
Waktu Paruh-
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Genetik -
small molecule | CAS: 87-51-4

Deskripsi belum tersedia.

Kategori:
Growth SubstancesHeterocyclic Compounds, Fused-RingIndoles +1
Target Protein:
Group IIE secretory phospholipase A2S-phase kinase-associated protein 1Kynurenine--oxoglutarate transaminase 1
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Genetik -
small molecule | CAS: 830-96-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +2
Target Protein:
Group IIE secretory phospholipase A2Aspartate aminotransferaseAromatic-amino-acid aminotransferase
Waktu Paruh-
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Genetik -
Indomethacin Approved DB00328
small molecule | CAS: 53-86-1

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an ind…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +49
Target Protein:
Prostaglandin G/H synthase 2Phospholipase A2, membrane associatedHuman Cyclooxygenases +8
Waktu ParuhIndometacin disposi…
Vol. DistribusiThe volume of distr…
KlirensIn a clinical pharm…
Genetik -
Indopan DB01446
small molecule | CAS: 299-26-3

Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use a…

Kategori:
AminesBiogenic AminesBiogenic Monoamines +3
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Indoprofen DB08951
small molecule | CAS: 31842-01-0

A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +18
Target Protein:
C-X-C chemokine receptor type 1Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1 +3
Waktu Paruh2.3 hours.
Vol. Distribusi-
KlirensRenal.
Genetik -
Indoramin Approved DB08950
small molecule | CAS: 26844-12-2

Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.

Kategori:
Acids, CarbocyclicAdrenergic AgentsAdrenergic alpha-1 Receptor Antagonists +16
Target Protein:
Alpha-1D adrenergic receptorAlpha-2C adrenergic receptorAlpha-2B adrenergic receptor +1
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Indotecan DB18752
small molecule | CAS: 915303-09-2

Deskripsi belum tersedia.

Kategori:
DioxolesDNA Topoisomerases, Type IHeterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
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Indoximod DB12827
small molecule | CAS: 110117-83-4

Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +2
Target Protein:
Indoleamine 2,3-dioxygenase 1
Waktu Paruh-
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Indoxyl sulfate DB07992
small molecule | CAS: 487-94-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Waktu Paruh-
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Indralin DB18220
small molecule | CAS: 156691-86-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesReceptors, Retinoic Acid, agonistsSulfur Compounds
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biotech | CAS: 1514889-12-3

Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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Inebilizumab Approved DB12530
biotech | CAS: 1299440-37-1

Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOSD).[A214283, A214286] …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +12
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhInebilizumab exhibi…
Vol. DistribusiInebilizumab has an…
KlirensInebilizumab has an…
Genetik -
Inecalcitol DB04796
small molecule | CAS: 163217-09-2

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesFused-Ring Compounds +9
Target Protein:
Vitamin D3 receptor
Waktu Paruh-
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Inetetamab DB17457
biotech

Inetetamab is a trastuzumab analog. It differs from trastuzumab by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of trastuzumab.

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Infigratinib Approved DB11886
small molecule | CAS: 872511-34-7

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth.[A235174] Cholangiocarcinoma is the most com…

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +24
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3 +1
Waktu ParuhThe geometric mean …
Vol. DistribusiAt steady state, th…
KlirensThe geometric mean …
Genetik -
Infliximab Approved DB00065
biotech | CAS: 170277-31-3

Infliximab is a tumor necrosis factor (TNF-alpha or TNF-?) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. Infliximab is produced by a recombinant cell line cultured by continuous pe…

Kategori:
Agents Causing Muscle ToxicityAgents reducing cytokine levelsAmino Acids, Peptides, and Proteins +21
Target Protein:
Tumor necrosis factor
Gen Terkait:
FCGR3A
Waktu ParuhThe median terminal…
Vol. DistribusiBased on a pharmaco…
KlirensIn patients with Cr…
Genetik 1 Varian
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

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Vol. Distribusi-
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Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +3
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Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
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biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInfluenza VaccinesLive Attenuated Influenza A Virus Vaccine +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Menampilkan 7401–7450 dari 14063
Sebelumnya Halaman 149 / 282 Berikutnya