Hasil Filter

15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (15718)

Halaman 148 / 315
Glycerin Approved DB09462
small molecule | CAS: 56-81-5

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

Kategori:
AlcoholsAlimentary Tract and MetabolismBasic Ointments and Protectants +21
Target Protein:
Peroxisome proliferator-activated receptor deltaGroup IIE secretory phospholipase A2Inositol-3-phosphate synthase 1 +11
Waktu Paruh30 - 45 minutes
Vol. DistribusiGlycerin is distrib…
Klirens-
Genetik -
small molecule | CAS: 17181-54-3

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesLipids +5
Target Protein:
Triosephosphate isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycerol phenylbutyrate Approved DB08909
small molecule | CAS: 611168-24-2

Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

Kategori:
Acids, CarbocyclicAlcoholsAlimentary Tract and Metabolism +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 614-33-5

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene Derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 111-03-5

Deskripsi belum tersedia.

Kategori:
Lipids
Target Protein:
Glucose-dependent insulinotropic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 27215-38-9

Deskripsi belum tersedia.

Kategori:
Cariostatic AgentsCompounds used in a research, industrial, or household settingFatty Acids +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glyceryl monocaprylate Approved DB19362
small molecule | CAS: 26402-26-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsLipids +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 31566-31-1

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.

Kategori:
Lipids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2752-99-0

Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 122-32-7

Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

Kategori:
FatsFats, UnsaturatedGlycerides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycinamide DB03636
small molecule | CAS: 598-41-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
Target Protein:
Neutrophil collagenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycine Approved DB00145
small molecule | CAS: 56-40-6

A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBlood and Blood Forming Organs +7
Target Protein:
Glutamate receptor ionotropic, NMDA 2A2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial5-aminolevulinate synthase, non-specific, mitochondrial +22
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 640-79-9

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +12
Target Protein:
7-alpha-hydroxysteroid dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 475-31-0

The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +11
Target Protein:
Gastrotropin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycocyamine DB02751
small molecule | CAS: 352-97-6

Deskripsi belum tersedia.

Kategori:
Affinity LabelsAmino AcidsAmino Acids, Peptides, and Proteins +3
Target Protein:
Guanidinoacetate N-methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycol salicylate Approved DB11323
small molecule | CAS: 87-28-5

Glycol salicylate, also known as _2-hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic …

Kategori:
Acids, CarbocyclicAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-Steroidal +5
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu ParuhThe serum half-life…
Vol. Distribusi-
Klirens-
Genetik -
Glycolic acid Approved DB03085
small molecule | CAS: 79-14-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicDermatologicals +2
Target Protein:
Glucose-6-phosphate 1-dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycopyrronium Approved DB00986
small molecule | CAS: 740028-90-4

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.[L33110] It is one of the most commonly prescribed anticholinergic medi…

Kategori:
Adjuvants, AnesthesiaAdrenergics, InhalantsAgents producing tachycardia +30
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2 +2
Waktu ParuhThe half life after…
Vol. DistribusiThe mean volume of …
KlirensA 6 µg/kg intraveno…
Genetik -
Glycovir DB13106
small molecule | CAS: 131262-82-3

Glycovir has been used in trials studying the treatment of HIV Infections.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Target Protein:
Maltase-glucoamylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
D-alanyl-D-alanine carboxypeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prolyl tripeptidyl peptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycylglutamine DB15990
small molecule | CAS: 13115-71-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsNeural InhibitionOligopeptides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycyltyrosine DB15991
small molecule | CAS: 658-79-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycyrrhiza glabra Approved DB14312
biotech | CAS: 84775-66-6

Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsBiological ProductsCell-mediated Immunity +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycyrrhizic acid Approved DB13751
small molecule | CAS: 1405-86-3

Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_.[F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it ca…

Kategori:
Alimentary Tract and MetabolismAnti-Inflammatory AgentsBile and Liver Therapy +6
Target Protein:
11-beta-hydroxysteroid dehydrogenase 1Tumor necrosis factorCaspase-3 +2
Waktu ParuhDepending on the do…
Vol. DistribusiThe apparent volume…
KlirensThe constant reabso…
Genetik -
Glymidine Approved DB01382
small molecule | CAS: 339-44-6

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be depende…

Kategori:
Alimentary Tract and MetabolismAmidesBlood Glucose Lowering Agents +7
Target Protein:
ATP-sensitive inward rectifier potassium channel 1ATP-sensitive inward rectifier potassium channel 10ATP-binding cassette sub-family C member 8
Waktu Paruh4 hours.
Vol. Distribusi-
Klirens-
Genetik -
Glyoxylic acid DB04343
small molecule | CAS: 298-12-4

Deskripsi belum tersedia.

Kategori:
Acids, Aldehydic
Target Protein:
Malate synthase GIsocitrate lyaseMalate synthase G +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glyphosate DB04539
small molecule | CAS: 1071-83-6

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAmino AcidsAmino Acids, Peptides, and Proteins +9
Target Protein:
Aromatase3-phosphoshikimate 1-carboxyvinyltransferase3-phosphoshikimate 1-carboxyvinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glypromate DB05633
small molecule | CAS: 32302-76-4

Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by …

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GMA-161 DB15397
biotech | CAS: 946415-70-9

GMA-161 is under investigation in clinical trial NCT00244257 (Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GMI-1359 DB18092
biotech

GMI-1359 is a small molecule, glycomimetic compound with dual inhibitory activity against E-selectin and CXCR4.[A261406]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GMK DB06661
biotech

GMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GMX1777 DB05217
small molecule

GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact me…

Kategori:
Amidines
Target Protein:
Nicotinamide phosphoribosyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

The GnRH pharmaccine consists of synthetic peptides (constructed to "look like" GnRH), which are bound chemically to a carrier and suspended in a proprietary "delivery vehicle". The pharmaccine is administered intramuscularly to the patient by injection and i…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GO-203-2C DB15008
small molecule | CAS: 1469735-88-3

GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Go-6976 DB17029
small molecule | CAS: 136194-77-9

An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingIndoles +1
Target Protein:
Transcription factor RelBNuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Goat milk Approved DB10542
biotech

Goat milk allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Goflikicept DB16396
biotech | CAS: 2416984-26-2

Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) …

Kategori:
Experimental Unapproved Treatments for COVID-19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golcadomide DB18115
small molecule | CAS: 2379572-34-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gold DB14154
small molecule | CAS: 7440-57-5

A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in t…

Kategori:
Cell-mediated ImmunityElementsGold Compounds +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gold Au-198 DB13427
small molecule | CAS: 10043-49-9

Deskripsi belum tersedia.

Kategori:
Anti-Inflammatory AgentsElementsGold Isotopes +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 20681-14-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15283-45-1

Deskripsi belum tersedia.

Kategori:
Antirheumatic AgentsGold CompoundsSodium Compounds +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Goldenseal Approved DB16594
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golexanolone DB18200
small molecule | CAS: 2089238-18-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golidocitinib DB18057
small molecule | CAS: 2091134-68-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golimumab Approved DB06674
biotech | CAS: 476181-74-5

Golimumab is a human IgG1? monoclonal antibody derived from immunizing genetically engineered mice with human TNF?. Golimumab binds and inhibits soluble and transmembrane human TNF?. Increased TNF? is associated with chronic inflammation. Thus golimumab is in…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAnti-Inflammatory Agents +17
Target Protein:
Tumor necrosis factor
Waktu ParuhGolimumab has a lon…
Vol. DistribusiAfter IV administra…
KlirensAfter one IV dose o…
Genetik -
biotech | CAS: 957472-14-9

Deskripsi belum tersedia.

Kategori:
Gene Transfer TechniquesNucleic AcidsNucleic Acids, Nucleotides, and Nucleosides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 7351–7400 dari 15718
Sebelumnya Halaman 148 / 315 Berikutnya