Hasil Filter

17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (17430)

Halaman 146 / 349
Epcoritamab Approved DB16672
biotech | CAS: 2134641-34-0

Epcoritamab is an IgG1-bispecific antibody that simultaneously binds to CD3 on T-cells and CD20 on B-cells.[A259736,A258488,A259761,L46516] Epcoritamab promotes the activation and expansion of T-cells and, by being able to bind to both CD20 and CD3, it leads …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +13
Target Protein:
B-lymphocyte antigen CD20T-cell surface glycoprotein CD3 epsilon chain
Waktu ParuhA full dose of epco…
Vol. DistribusiEpcoritamab has an …
KlirensA full dose of epco…
Genetik -
Epeleuton DB18100
small molecule | CAS: 1667760-39-5

Deskripsi belum tersedia.

Kategori:
Dietary FatsDietary Fats, UnsaturatedEicosanoids +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epelsiban DB11934
small molecule | CAS: 872599-83-2

Epelsiban has been investigated for the treatment of Premature Ejaculation.

Kategori:
OxazinesPiperazines
Target Protein:
Oxytocin receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eperisone DB08992
small molecule | CAS: 64840-90-0

Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAutonomic Agents +20
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epetraborole DB11744
small molecule | CAS: 1093643-37-8

Epetraborole has been used in trials studying the treatment of Infections, Bacterial, Infections, Intestinal, Infections, Urinary Tract, and Community-acquired Infection.

Kategori:
Anti-Bacterial AgentsLeucine-tRNA Ligase, antagonists & inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Ephedra is an alkaloid chemical compound traditionally obtained from the plant _Ephedra sinica_. The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for a…

Kategori:
Adrenergic AgonistsAdrenergic alpha-2 Receptor AgonistsAdrenergic alpha-Agonists +22
Target Protein:
Sodium-dependent dopamine transporterSodium-dependent noradrenaline transporterAlpha-2A adrenergic receptor +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Biological ProductsComplex MixturesCycadopsida +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ephedrine Approved DB01364
small molecule | CAS: 299-42-3

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].[A193698] Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic rece…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-Agonists +39
Target Protein:
D(2) dopamine receptorAlpha-1A adrenergic receptorBeta-1 adrenergic receptor +2
Waktu ParuhOral ephedrine has …
Vol. DistribusiOral ephedrine has …
KlirensOral ephedrine has …
Genetik -
small molecule | CAS: 1082659-36-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
EPI-589 DB16041
small molecule | CAS: 1147883-03-1

EPI-589 is under investigation in clinical trial NCT02460679 (Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epibatidine DB07720
small molecule | CAS: 140111-52-0

Deskripsi belum tersedia.

Kategori:
AnalgesicsAnalgesics, Non-NarcoticCentral Nervous System Agents +6
Target Protein:
CHRNA7-FAM7A fusion proteinNeuronal acetylcholine receptor subunit alpha-7Neuronal acetylcholine receptor subunit beta-2 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicaptopril DB02032
small molecule | CAS: 63250-36-2

Deskripsi belum tersedia.

Kategori:
Agents that produce hypertensionAmino AcidsAmino Acids, Cyclic +6
Target Protein:
Metallo-beta-lactamase L1Beta-lactamaseOrganic hydroperoxide resistance protein, putative +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicatechin DB12039
small molecule | CAS: 490-46-0

Epicatechin has been used in trials studying the treatment of Pre-diabetes.

Kategori:
BenzopyransCatechinChromans +4
Target Protein:
Prostaglandin G/H synthase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicept NP-1 DB05492
small molecule

EpiCept NP-1 is a prescription topical analgesic cream designed to provide effective, long-term relief from the pain of peripheral neuropathies. Peripheral neuropathies are medical conditions caused by damage to the nerves in the peripheral nervous system. Th…

Target Protein:
Mu-type opioid receptor5-hydroxytryptamine receptor 2A5-hydroxytryptamine receptor 2B +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicillin DB13300
small molecule | CAS: 26774-90-3

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicoccum nigrum Approved DB10434
biotech

Epicoccum nigrum is a fungus which can provoke allergic reactions. Epicoccum nigrum extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epicriptine Approved DB11275
small molecule | CAS: 88660-47-3

Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from th…

Kategori:
AlkaloidsDopamine Agonists
Target Protein:
Dopamine receptor
Waktu ParuhPlease refer to [DB…
Vol. DistribusiPlease refer to [DB…
KlirensPlease refer to [DB…
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epidermophyton floccosum Approved DB10870
biotech

Epidermophyton floccosum is a fungus which can provoke allergic reactions. Epidermophyton floccosum extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 25615-05-8

Epigallo Catechin Gallate is under investigation in clinical trial NCT00799890 (Sunphenon in Progressive Forms of Multiple Sclerosis).

Kategori:
BenzopyransChromansChromones +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 970-74-1

Deskripsi belum tersedia.

Kategori:
BenzopyransChromansChromones +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 989-51-5

Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.

Kategori:
Anticarcinogenic AgentsAntimutagenic AgentsAntineoplastic Agents +13
Target Protein:
Fatty acid synthaseSignal transducer and activator of transcription 3Gag-Pol polyprotein +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Epimedium grandiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epimestrol DB13386
small molecule | CAS: 7004-98-0

Deskripsi belum tersedia.

Kategori:
EstranesEstrenesEstrogens +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epinastine Approved DB00751
small molecule | CAS: 80012-43-7

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic respon…

Kategori:
Acid ReducersAntidepressive AgentsCentral Nervous System Depressants +27
Target Protein:
Histamine H1 receptorHistamine H2 receptorAlpha-1A adrenergic receptor +3
Waktu Paruh12 hours
Vol. Distribusi-
Klirens* 56 L/hr [patients…
Genetik -
Epinephrine Approved DB00668
small molecule | CAS: 51-43-4

Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, …

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +52
Target Protein:
Alpha-1A adrenergic receptorAlpha-1B adrenergic receptorBeta-1 adrenergic receptor +5
Waktu ParuhThe plasma half-lif…
Vol. Distribusi-
KlirensIntravenous injecti…
Genetik -
Epirizole DB08991
small molecule | CAS: 18694-40-1

Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epirubicin Approved DB00445
small molecule | CAS: 56420-45-2

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

Kategori:
Anthracycline Topoisomerase InhibitorAnthracyclinesAnthracyclines and Related Substances +17
Target Protein:
DNA topoisomerase 2-betaDNADNA topoisomerase 2-alpha
Waktu ParuhHalf-lives for the …
Vol. Distribusi* 21 ± 2 L/kg [60 m…
Klirens* 65 +/- 8 L/hour […
Genetik -
Epitalon DB17882
small molecule | CAS: 307297-39-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Telomerase reverse transcriptase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epitestosterone DB07768
small molecule | CAS: 481-30-1

Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epit…

Kategori:
AndrostanesAndrostenesAndrostenols +7
Target Protein:
Aldo-keto reductase family 1 member C1Aldo-keto reductase family 1 member C2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epitizide DB13989
small molecule | CAS: 1764-85-8

Epitizide is an agent, commonly found in combination [triamterene], used to produce diuresis.

Kategori:
DiureticsLow-Ceiling Diuretics and Potassium-Sparing AgentsSodium Chloride Symporter Inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
EpiVacCorona DB16439
biotech

EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus[L30608]. It is currently being tested in Phase I/II clinical trials for …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eplerenone Approved DB00700
small molecule | CAS: 107724-20-9

Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. Th…

Kategori:
Agents causing hyperkalemiaAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension +19
Target Protein:
Mineralocorticoid receptor
Waktu Paruh4-6 hours
Vol. Distribusi* 43 to 90 L
Klirens* Apparent plasma c…
Genetik -
Eplivanserin DB12177
small molecule | CAS: 130579-75-8

Eplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others.

Kategori:
Antidepressive AgentsBenzene DerivativesCardiovascular Agents +8
Target Protein:
5-hydroxytryptamine receptor 2A5-hydroxytryptamine receptor 2C
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eplontersen Approved DB16199
biotech | CAS: 1637600-16-8

Eplontersen is a transthyretin-directed antisense oligonucleotide with 3 covalently linked e N-acetyl galactosamine residues for hepatic delivery. It was previously investigated as a potential treatment for hereditary transthyretin-mediated amyloidosis.[A2629…

Kategori:
Antisense OligonucleotidesNervous SystemNucleic Acids, Nucleotides, and Nucleosides +3
Target Protein:
Transthyretin mRNA
Waktu ParuhThe terminal elimin…
Vol. DistribusiEplontersen is expe…
KlirensThe clearance was e…
Genetik -
Epoetin beta DB19434
biotech | CAS: 122312-54-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCarbohydrates +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epoetin delta Approved DB11624
biotech | CAS: 261356-80-3

Epoetin Delta is an ingredient in the EMA-withdrawn product Dynepo.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCarbohydrates +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epofolate DB12266
small molecule | CAS: 958646-17-8

Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. In Phase I/IIa…

Kategori:
Anti-Bacterial AgentsAntineoplastic AgentsCytochrome P-450 CYP3A Inhibitors +9
Target Protein:
Folate receptor alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epomediol DB13802
small molecule | CAS: 1310101-21-3

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyCholagogues and Choleretics +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epoprostenol Approved DB01240
small molecule | CAS: 35121-78-9

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.

Kategori:
AnticoagulantsAntihypertensive AgentsAntiplatelet agents +19
Target Protein:
Prostacyclin synthaseP2Y purinoceptor 12Prostacyclin receptor
Waktu ParuhThe in vitro half-l…
Vol. Distribusi* 357 mL/kg
Klirens-
Genetik -
Epothilone D DB01873
small molecule | CAS: 189453-10-9

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsAntimitotic AgentsAntineoplastic Agents +9
Target Protein:
Tubulin beta chainTubulin beta-1 chainTubulin beta-4B chain +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Epratuzumab DB04958
biotech | CAS: 205923-57-5

Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Target Protein:
B-cell receptor CD22
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprazinone DB08990
small molecule | CAS: 10402-90-1

Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.

Kategori:
Cough and Cold PreparationsExpectorantsKetones +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprenetapopt DB11684
small molecule | CAS: 5291-32-7

Eprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.

Target Protein:
Cellular tumor antigen p53
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprinomectin DB11405
small molecule | CAS: 123997-26-2

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAnthelminticsAnti-Bacterial Agents +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprodisate DB06405
small molecule | CAS: 21668-77-9

Eprodisate slows the decline of renal function in AA amyloidosis.

Kategori:
AcidsAcids, NoncarboxylicAlkanes +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprosartan Approved DB00876
small molecule | CAS: 133040-01-4

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting no…

Kategori:
Acids, AcyclicAgents Acting on the Renin-Angiotensin SystemAgents causing angioedema +13
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhThe terminal elimin…
Vol. Distribusi-
Klirens-
Genetik -
Eprotirome DB05035
small molecule | CAS: 355129-15-6

Eprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.

Kategori:
AmidesAminesAniline Compounds
Target Protein:
Thyroid hormone receptor alphaThyroid hormone receptor beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eprozinol DB13395
small molecule | CAS: 32665-36-4

Deskripsi belum tersedia.

Kategori:
Drugs for Obstructive Airway Diseases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1188-07-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 7251–7300 dari 17430
Sebelumnya Halaman 146 / 349 Berikutnya