Hasil Filter

15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (15718)

Halaman 146 / 315
Gevokizumab DB12119
biotech | CAS: 1129435-60-4

Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease sta…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Interleukin-1 beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GFH-925 DB17481
small molecule

GFH-925 is an irreversibly covalent inhibitor of KRAS G12C.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GFT14 DB05061
small molecule

GFT14 is a new class of medicaction for treatment of cardiometabolic disease. GFT14 aims to target mixed dyslipidemia of type IIb (high levels of triglycerides and LDL-C) as one of the major indications of cardiometabolic disease. GFT14 is destined to improv…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI heptapeptide DB15070
biotech

GI heptapeptide is under investigation in clinical trial NCT01391208 (Esophageal Protocol for Detection of Neoplasia in the Digestive Tract).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-101 DB17243
biotech

GI-101 is a bi-specific fragment crystallizable region (Fc) fusion protein containing a cluster of differentiation 80 ectodomain as an N-terminal moiety and interleukin-2 variant as a C-terminal moiety conjugated with human immunoglobulin G4 Fc.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-181771X DB12309
small molecule | CAS: 305366-98-7

Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food Intake in Humans).

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-RingReceptor, Cholecystokinin A, agonists
Target Protein:
Cholecystokinin receptor type A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-4000 DB05698
biotech

A vaccine containing a heat-killed recombinant <em>Saccharomyces cerevisiae</em> yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant and antitumor activity. [L112]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-5005 DB05942
biotech | CAS: 1001913-27-4

GI-5005 is GlobeImmune's lead infectious disease product from its proprietary Tarmogen active immunotherapy platform for the treatment of chronic hepatitis C infection. GI-5005 is whole, heat-killed recombinant yeast genetically modified to express HCV-specif…

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-6207 DB17532
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntigensAntigens, Neoplasm +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GI-6301 DB17533
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gibberella fujikuroi Approved DB15511
biotech

Gibberella fujikuroi allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 77-06-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsDiterpene AlkaloidsDiterpenes +5
Target Protein:
Arylacetamide deacetylase-like 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gibberellin A4 DB07815
small molecule | CAS: 468-44-0

Deskripsi belum tersedia.

Kategori:
AlkaloidsDiterpene AlkaloidsDiterpenes +2
Target Protein:
Arylacetamide deacetylase-like 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gildeuretinol DB18468
small molecule | CAS: 118139-36-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Giloralimab DB18862
biotech | CAS: 2226292-20-0

Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV B…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gilteritinib Approved DB12141
small molecule | CAS: 1254053-43-4

Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.[A40036] It is a pyrazinecarboxamide derivative that showed h…

Kategori:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +16
Target Protein:
Receptor-type tyrosine-protein kinase FLT3Tyrosine-protein kinase receptor UFOALK tyrosine kinase receptor +1
Waktu ParuhThe reported median…
Vol. DistribusiThe estimated appar…
KlirensThe estimated clear…
Genetik -
Gimatecan DB06721
small molecule | CAS: 292618-32-7

Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.

Kategori:
AlkaloidsOATP1B1/SLCO1B1 Substrates
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gimeracil Approved DB09257
small molecule | CAS: 103766-25-2

Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. Approved by the European Medicines Agency (EMA) in March 2011, Gimeracil is available in combination wi…

Kategori:
Drugs that are Mainly Renally Excreted
Target Protein:
Dihydropyrimidine dehydrogenase [NADP(+)]
Waktu ParuhFollowing a single …
Vol. DistribusiAlthough no intrave…
Klirens-
Genetik -
Gimsilumab DB15280
biotech | CAS: 1648796-29-5

Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAnti-Inflammatory Agents +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginger Approved DB10344
biotech

Ginger allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityHerbs and Natural ProductsIncreased Histamine Release +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginger oil Approved DB14690
biotech | CAS: 8007-08-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gingerol DB19255
small molecule | CAS: 23513-14-6

Gingerol is under investigation in clinical trial NCT05882864 (Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysis).

Kategori:
AlcoholsBenzene DerivativesLipids +2
Target Protein:
Transient receptor potential cation channel subfamily A member 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginisortamab DB18863
biotech | CAS: 2390147-17-6

Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginkgo biloba Approved DB01381
biotech | CAS: 90045-36-6

_Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties.[A232389] Most of the studies t…

Kategori:
Anti-Dementia DrugsBiological ProductsBlood Circulation +27
Target Protein:
Sodium-dependent noradrenaline transporterPhospholipase A2, membrane associatedGlycine receptor subunit alpha-1 +5
Waktu ParuhUnpublished human d…
Vol. DistribusiNo data available.
KlirensNo data available.
Genetik -
biotech

Ginkgo biloba leaf oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginkgolide A DB06743
small molecule | CAS: 15291-75-5

Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.

Kategori:
DiterpenesTerpenes
Target Protein:
Glycine receptor subunit alpha-1Glycine receptor subunit alpha-2Glycine receptor subunit alpha-3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ginkgolide-C DB06745
small molecule | CAS: 15291-76-6

Deskripsi belum tersedia.

Kategori:
DiterpenesTerpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ginkgolide-J DB06746
small molecule | CAS: 107438-79-9

Deskripsi belum tersedia.

Kategori:
DiterpenesTerpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ginkgolide-M DB06747
small molecule | CAS: 15291-78-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginseng DB01404
biotech | CAS: 50647-08-0

Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.

Kategori:
AngiospermsAraliaceaeBiological Products +11
Target Protein:
Aryl hydrocarbon receptorInterleukin-6Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside B2 DB14815
small molecule | CAS: 52286-59-6

Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes).

Kategori:
CarbohydratesGlycosidesPanax +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside C DB06748
small molecule | CAS: 11021-13-9

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsCarbohydratesGlycosides +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside Rb1 DB06749
small molecule | CAS: 41753-43-9

Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. B…

Kategori:
CarbohydratesGlycosidesOATP1B3 inhibitors +4
Target Protein:
Solute carrier organic anion transporter family member 1B3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside Rd DB19256
small molecule | CAS: 52705-93-8

Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

Kategori:
CarbohydratesGlycosidesPanax +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside Rg1 DB06750
small molecule | CAS: 22427-39-0

Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. B…

Kategori:
CarbohydratesCentral Nervous System AgentsGlycosides +4
Target Protein:
Solute carrier organic anion transporter family member 1B3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenoside Rg3 DB19257
small molecule | CAS: 14197-60-5

Ginsenoside Rg3 is under investigation in clinical trial NCT01757366 (Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer).

Kategori:
Antineoplastic AgentsAntineoplastic Agents, PhytogenicCarbohydrates +5
Target Protein:
Voltage-gated inwardly rectifying potassium channel KCNH2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ginsenosides DB14152
small molecule | CAS: 74749-74-9

Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.

Kategori:
CarbohydratesGlycosidesSaponins +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Giredestrant DB19125
small molecule | CAS: 1953133-47-5

Giredestrant is under investigation in clinical trial NCT06065748 (A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With Er-positive, Her2-negative Advanced Breast Cancer Resistant to…

Kategori:
Heterocyclic Compounds, Fused-RingIndole AlkaloidsIndoles +1
Target Protein:
Estrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Girentuximab DB05304
biotech | CAS: 916138-87-9

Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
Target Protein:
Carbonic anhydrase 9Interleukin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1011710-99-8

Girentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Giripladib DB15426
small molecule | CAS: 865200-20-0

Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2166101-71-7

Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).

Kategori:
Adeno-associated Viral Vector Therapies
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gisadenafil DB11902
small molecule | CAS: 334826-98-1

Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia.

Kategori:
AmidesCyclic Nucleotide Phosphodiesterases, Type 5Pyrimidines +2
Target Protein:
cGMP-specific 3',5'-cyclic phosphodiesterase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gitoformate DB13537
small molecule | CAS: 10176-39-3

Deskripsi belum tersedia.

Kategori:
CarbohydratesCardanolidesCardenolides +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Givastomig DB18618
biotech

Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GIVI-MPC DB17905
biotech

GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Givinostat Approved DB12645
small molecule | CAS: 497833-27-9

Givinostat is a small molecule histone deacetylase (HDAC) inhibitor. It has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several…

Kategori:
Acids, AcyclicAminesAntineoplastic Agents +20
Target Protein:
Histone deacetylaseTyrosine-protein kinase JAK2Histone deacetylase 1
Waktu ParuhThe apparent plasma…
Vol. DistribusiAccording to popula…
KlirensAccording to popula…
Genetik -
Givosiran Approved DB15066
biotech | CAS: 1639325-43-1

Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway.[L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in Nove…

Kategori:
Alimentary Tract and MetabolismAmino SugarsAminolevulinate Synthase 1-directed RNA Interaction +13
Target Protein:
ALAS1 mRNA5-aminolevulinate synthase, non-specific, mitochondrial
Waktu ParuhBoth givosiran and …
Vol. DistribusiThe apparent centra…
KlirensThe apparent cleara…
Genetik -
GL-0719 DB18436
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GL-2045 DB16971
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 7251–7300 dari 15718
Sebelumnya Halaman 146 / 315 Berikutnya