Hasil Filter

12560

Total database: 17430
Struktur (SMILES)
9109 (72.5%)
Target
6912 (55.0%)
Genomik
109 (0.9%)
Referensi
12560 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (12560)

Halaman 143 / 252
KX-2361 DB17180
small molecule | CAS: 897016-26-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +6
Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Kynurenic Acid DB11937
small molecule | CAS: 492-27-3

Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).

Kategori:
Excitatory Amino Acid AgentsExcitatory Amino Acid AntagonistsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2BGlutamate receptor ionotropic, NMDA 2A +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1758-80-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Envelope glycoprotein gp160
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 73537-09-4

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Cysteine desulfuraseCystathionine gamma-lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 26630-55-7

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDicarboxylic Acids
Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-377202 DB19022
small molecule | CAS: 207395-85-5

L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-709,587 DB03621
small molecule

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-756423 DB02009
small molecule | CAS: 216863-66-0

Deskripsi belum tersedia.

Kategori:
Antiviral AgentsHIV Protease InhibitorsIndenes
Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-778123 DB07227
small molecule | CAS: 183499-57-2

Deskripsi belum tersedia.

Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-1 subunit beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Acetylleucine Approved DB16956
small molecule | CAS: 1188-21-2

Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo.[A264439] Observational studies in patients with Niemann-Pi…

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +7
Waktu ParuhThe half-life of le…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
Genetik -
small molecule | CAS: 1509-34-8

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 33049-08-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 1006685-44-4

C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal muscle breakdown. C-101 includes a carnitine carrier mole…

Target Protein:
Calpain-3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Arabinose DB16873
small molecule | CAS: 5328-37-0

Deskripsi belum tersedia.

Kategori:
ArabinoseCarbohydratesMonosaccharides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Baclofen DB12098
small molecule | CAS: 66514-99-6

L-Baclofen has been used in trials studying the treatment of Trigeminal Neuralgia.

Target Protein:
Gamma-aminobutyric acid type B receptor subunit 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carboxypeptidase A1ThermolysinRetinoid-inducible serine carboxypeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 118313-25-0

L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Eflornithine DB03856
small molecule | CAS: 66640-93-5

Deskripsi belum tersedia.

Target Protein:
Ornithine decarboxylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Gluconic Acid DB04304
small molecule | CAS: 526-97-6

Deskripsi belum tersedia.

Target Protein:
Beta-glucosidase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Glutamine Approved DB00130
small molecule | CAS: 56-85-9

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cel…

Kategori:
Alimentary Tract and MetabolismAmino AcidsAmino Acids and Derivatives +8
Target Protein:
CTP synthase 1AmidophosphoribosyltransferaseGlutamine synthetase
Waktu ParuhThe half life of el…
Vol. DistribusiVolume of distribut…
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesMonosaccharides
Target Protein:
Ferrichrome-iron receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 25679-93-0

Deskripsi belum tersedia.

Target Protein:
Histidinol-phosphate aminotransferaseHistidinol-phosphate aminotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-homoarginine DB03974
small molecule | CAS: 156-86-5

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +2
Target Protein:
Nitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Homoserine DB04193
small molecule | CAS: 672-15-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Lactic acid Approved DB14475
small molecule | CAS: 79-33-4

Deskripsi belum tersedia.

Kategori:
Hydroxy AcidsLactates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 120484-65-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 29586-66-1

L-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 62697-73-8

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2
Target Protein:
Thymidylate synthaseAmyloid-beta precursor proteinCatalase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Inositol monophosphatase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 80875-98-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6152-89-2

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiomarkers
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3182-95-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Rhamnitol DB02399
small molecule | CAS: 488-28-8

Deskripsi belum tersedia.

Target Protein:
L-rhamnose isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Saccharopine DB04207
small molecule | CAS: 997-68-2

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +1
Target Protein:
Alpha-aminoadipic semialdehyde synthase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-tartaric acid DB09459
small molecule | CAS: 87-69-4

Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

Kategori:
Acids, AcyclicCarbohydratesChelating Agents +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-thioproline DB02846
small molecule | CAS: 2756-91-4

Deskripsi belum tersedia.

Target Protein:
Annexin A5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-Threoninol DB01724
small molecule | CAS: 3228-51-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L-tyrosinamide DB03380
small molecule | CAS: 4985-46-0

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +1
Target Protein:
Pro-neuropeptide YValacyclovir hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 64913-51-5

Deskripsi belum tersedia.

Kategori:
CarbohydratesSugar Phosphates
Target Protein:
3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 60802-29-1

Deskripsi belum tersedia.

Target Protein:
3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carboxypeptidase A1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
L523S DB06498
biotech

According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) and when delivered following incorporation into an E1B-del…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Labetalol Approved DB00598
small molecule | CAS: 36894-69-6

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture.[L7730] Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 …

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +35
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorAlpha-1 adrenergic receptors
Waktu ParuhLabetalol has a hal…
Vol. DistribusiIn normotensive pat…
KlirensLabetalol has a pla…
Genetik -
Labetuzumab DB05097
biotech | CAS: 219649-07-7

Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Target Protein:
Cell adhesion molecule CEACAM5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Labradimil DB06549
small molecule | CAS: 159768-75-9

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +8
Target Protein:
B2 bradykinin receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Lacidipine Approved DB09236
small molecule | CAS: 103890-78-4

Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia [A31536]. It displays specificity in the vascular smooth muscle, whe…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +16
Target Protein:
Voltage-dependent L-type calcium channel
Waktu ParuhThe average termina…
Vol. Distribusi-
Klirens-
Genetik -
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