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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
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14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 143 / 282
HRS-1167 DB18703
small molecule

HRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).

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HSD-016 DB12419
small molecule | CAS: 946396-92-5

Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

Kategori:
Alcohols
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HSK-3486 DB16295
small molecule | CAS: 1637741-58-2

HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).

Kategori:
Benzene Derivatives
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HSV-2 theracine DB05811
biotech

HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes.

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HT-0712 DB11650
small molecule | CAS: 617720-02-2

BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).

Kategori:
Piperidines
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B
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HTPEP-001 DB18730
biotech

HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-?). It is being investigated for the treatment of fibrosis.[A263527]

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hu3S193 DB17213
biotech

Deskripsi belum tersedia.

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HUB-101 DB18656
biotech

Deskripsi belum tersedia.

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biotech

Human adenovirus b serotype 7 is a vaccine.

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biotech | CAS: 1822383-06-1

Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus Erythematosus).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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biotech

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Kategori:
AntigensAntigens, NeoplasmBiological Factors +3
Target Protein:
Histo-blood group ABO system transferase
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biotech

Infant botulism is a rare infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission…

Kategori:
Bacterial Neurotoxin NeutralizationHuman Immunoglobulin GPassively Acquired Immunity
Waktu ParuhThe half-life of hu…
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Human calcitonin Approved DB06773
biotech | CAS: 21215-62-3

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.[A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus …

Kategori:
Bone Density Conservation AgentsCalcitonin PreparationsCalcium Homeostasis +1
Target Protein:
Alpha-actinin-1
Waktu ParuhIntravenous adminis…
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KlirensThe metabolic clear…
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biotech

Human ciliary neurotrophic factor, recombinant was investigated for macular telangiectasia in two clinical trials. The trials were NCT03071965, an extension study of the NT-501 CNTF implant for macular telangiectasia, and NCT01949324, a Phase 2 multicenter ra…

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Human colostrum DB19286
biotech

Deskripsi belum tersedia.

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biotech

Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures…

Kategori:
Allogeneic Cord Blood Hematopoietic Progenitor Cell Therapy
Waktu ParuhPharmacokinetic par…
Vol. DistribusiPharmacokinetic par…
KlirensPharmacokinetic par…
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biotech | CAS: 339086-15-6

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntiinfectives for Systemic Use +15
Waktu ParuhIgG1 has a half-lif…
Vol. DistribusiIgG is distributed …
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biotech

Deskripsi belum tersedia.

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biotech | CAS: 259230-56-3

Human growth hormone-releasing peptide 3 is under investigation in clinical trial NCT00846872 (Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance).

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Human immunoglobulin G Approved DB00028
biotech | CAS: 308067-58-5

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatogra…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntigen Neutralization +13
Target Protein:
High affinity immunoglobulin gamma Fc receptor IPutative high affinity immunoglobulin gamma Fc receptor IBLow affinity immunoglobulin gamma Fc region receptor II-a +8
Waktu Paruh>20 hours (mammalia…
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Human interferon beta Approved DB14999
biotech | CAS: 74899-71-1

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992.[L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and s…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsBiological Factors +7
Target Protein:
Interferon alpha/beta receptor 1
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe average state v…
KlirensAverage serum clear…
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biotech

Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are m…

Kategori:
Immunosuppressive AgentsMyelosuppressive Agents
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
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biotech

Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +17
Target Protein:
Interleukin-8
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biotech

Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).

Kategori:
Amino Acids, Peptides, and ProteinsAnalgesicsAnalgesics, Non-Narcotic +12
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biotech

Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
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biotech | CAS: 183623-03-2

Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).

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biotech

Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
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biotech

Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsCancer immunotherapy +9
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biotech

Deskripsi belum tersedia.

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biotech

Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
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biotech

Deskripsi belum tersedia.

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biotech

Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 5…

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age f…

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
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biotech

Deskripsi belum tersedia.

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biotech

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Human thrombin Approved DB11571
biotech | CAS: 9002-04-4

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This tra…

Kategori:
Blood Coagulation FactorsIncreased Coagulation Factor Activity
Target Protein:
Coagulation factor VCoagulation factor VIIICoagulation factor XI +5
Waktu ParuhDue to the nature o…
Vol. DistribusiDue to the nature o…
KlirensDue to the nature o…
Genetik -
biotech

Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines thes…

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biotech

Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marro…

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biotech

Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +10
Waktu ParuhThe mean half-life …
Vol. DistribusiThe volume of distr…
KlirensReadily accessible …
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biotech

Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma vi…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBiological Products +13
Waktu ParuhHuman Varicella-Zos…
Vol. DistribusiFollowing intraveno…
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biotech

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biotech

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The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that…

Target Protein:
Interleukin-12 subunit beta
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Huperzine A Approved DB04864
small molecule | CAS: 102518-79-6

Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss _Huperzia serrata_. The botanical has been used in China for centuries for the treatment of swelling, fever and blood disorders. Recently in clinical trials in C…

Kategori:
Central Nervous System AgentsCholinergic AgentsCholinesterase Inhibitors +6
Target Protein:
Acetylcholinesterase
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Huperzine B DB03348
small molecule | CAS: 103548-82-9

Huperzine B is a novel acetylcholinesterase inhibitor.

Kategori:
Drugs, Chinese HerbalPlant Extracts
Target Protein:
Acetylcholinesterase
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