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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (14063)

Halaman 141 / 282
Haloperidol Approved DB00502
small molecule | CAS: 52-86-8

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.[A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A274…

Kategori:
Agents that reduce seizure thresholdAnti-Dyskinesia AgentsAntidepressive Agents +50
Target Protein:
5-hydroxytryptamine receptor 2CD(2) dopamine receptor5-hydroxytryptamine receptor 2A +15
Waktu ParuhFollowing oral admi…
Vol. DistribusiThe apparent volume…
KlirensFollowing intraveno…
Genetik -
Halothane Approved DB01159
small molecule | CAS: 151-67-7

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxatio…

Kategori:
Agents that produce hypertensionAnestheticsAnesthetics, General +14
Target Protein:
Potassium channel subfamily K member 3Potassium channel subfamily K member 9GABA(A) Receptor +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxazolam DB01476
small molecule | CAS: 59128-97-1

Deskripsi belum tersedia.

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxon DB11419
small molecule | CAS: 321-55-1

Deskripsi belum tersedia.

Kategori:
BenzopyransCoumarinsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxyfop-P DB07870
small molecule | CAS: 95977-29-0

Deskripsi belum tersedia.

Target Protein:
Acetyl-CoA carboxylase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Harmaline DB13875
small molecule | CAS: 304-21-2

Deskripsi belum tersedia.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAlkaloids +14
Target Protein:
Histamine N-methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Harmine DB07919
small molecule | CAS: 442-51-3

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntidepressive AgentsCarbolines +13
Target Protein:
Dual specificity tyrosine-phosphorylation-regulated kinase 2Dual specificity tyrosine-phosphorylation-regulated kinase 3Dual specificity tyrosine-phosphorylation-regulated kinase 1A +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HE-2200 DB06257
small molecule | CAS: 2697-85-0

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesFused-Ring Compounds +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HE3286 DB05212
small molecule | CAS: 1001100-69-1

Deskripsi belum tersedia.

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12
Target Protein:
Nuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Helium Approved DB09155
small molecule | CAS: 7440-59-7

Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table. Its boiling and melting …

Kategori:
ElementsGasesMedical Gases +3
Waktu Paruh0.8 seconds
Vol. Distribusi-
Klirens-
Genetik -
Helium He-3 DB12940
small molecule | CAS: 14762-55-1

Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI).

Kategori:
ElementsGasesNoble Gases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hematoxylin DB16871
small molecule | CAS: 517-28-2

Deskripsi belum tersedia.

Kategori:
BenzopyransColoring AgentsCompounds used in a research, industrial, or household setting +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heme arginate DB17310
biotech | CAS: 100438-92-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemicellulase DB15820
biotech | CAS: 9025-56-3

Deskripsi belum tersedia.

Kategori:
EnzymesEnzymes and CoenzymesHydrolases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoglobin Approved DB04945
biotech | CAS: 9008-02-0

The respiratory protein of the red blood cells. It consists primarily of globin and heme.

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsGlobins +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 142261-03-8

Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.

Kategori:
Amino Acids, Peptides, and ProteinsBenzene DerivativesBlood and Blood Forming Organs +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 192230-36-7

Hemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).

Kategori:
Amino Acids, Peptides, and ProteinsBiomimetic MaterialsBlood Proteins +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 679404-95-6

Hemoglobin glutamer-256 (human) is under investigation in clinical trial NCT00076648 (Safety and Efficacy of Polyheme(r) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-hospital Setting).

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsBlood Substitutes +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 197462-97-8

Deskripsi belum tersedia.

Kategori:
Blood and Blood Forming OrgansBlood and Related ProductsBlood Substitutes and Perfusion Solutions +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemopexin DB18229
biotech

Deskripsi belum tersedia.

Kategori:
Acute-Phase ProteinsAmino Acids, Peptides, and ProteinsBeta-Globulins +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoporfin DB16183
small molecule | CAS: 14459-29-1

Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).

Kategori:
Biological FactorsDermatologicalsHeterocyclic Compounds, Fused-Ring +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoximer DB17600
biotech

Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.[A258528]

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsBlood Proteins +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Henagliflozin DB11939
small molecule | CAS: 1623804-44-3

Henagliflozin has been used in trials studying the treatment of Type 2 Diabetes.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Henatinib DB13019
small molecule | CAS: 1239269-51-2

Henatinib has been used in trials studying the treatment of Advanced Solid Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingVascular Endothelial Growth Factors, antagonists & inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
C-C motif chemokine 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
C-C motif chemokine 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heparin, bovine DB15404
small molecule | CAS: 9005-49-6

Heparin, bovine is under investigation in clinical trial NCT01072747 (Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hepatitis A Vaccine Approved DB10989
biotech

Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure.[A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has bee…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +4
Target Protein:
B-lymphocytes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hepatitis B immune globulin Approved DB05276
biotech

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatit…

Kategori:
Amino Acids, Peptides, and ProteinsAntiinfectives for Systemic UseBlood Proteins +12
Target Protein:
HBsAg
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsAntigens +19
Waktu ParuhEvaluation of pharm…
Vol. DistribusiEvaluation of pharm…
KlirensEvaluation of pharm…
Genetik -
Hepcidin-25 DB19226
biotech | CAS: 1356390-47-0

Hepcidin-25 is under investigation in clinical trial NCT03381833 (A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-dependent Beta Thalassemia).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HEPES DB16872
small molecule | CAS: 7365-45-9

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsBuffers +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5617-32-3

Deskripsi belum tersedia.

Kategori:
Pegylated agents
Target Protein:
Carbonyl reductase [NADPH] 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptaminol DB13574
small molecule | CAS: 372-66-7

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptanamide DB02641
small molecule | CAS: 628-62-6

Deskripsi belum tersedia.

Target Protein:
Limonene-1,2-epoxide hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsLipids
Target Protein:
RhodopsinFimbrial proteinFe(3+) dicitrate transport protein FecA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptanoic acid DB02938
small molecule | CAS: 111-14-8

Deskripsi belum tersedia.

Target Protein:
Phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle form
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 78617-12-6

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1APeroxisome proliferator-activated receptor delta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HER-902 DB17948
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hesperetin DB01094
small molecule | CAS: 520-33-2

Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.

Kategori:
BCRP/ABCG2 InhibitorsBenzopyransCarbohydrates +8
Target Protein:
Diacylglycerol O-acyltransferase 1Microsomal triglyceride transfer protein large subunitSterol O-acyltransferase 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hesperidin Approved DB04703
small molecule | CAS: 520-26-3

Hesperidin is a flavan-on glycoside found in citrus fruits.

Kategori:
BenzopyransCarbohydratesChromones +5
Target Protein:
Voltage-dependent N-type calcium channel subunit alpha-1BAurora kinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24292-52-2

Deskripsi belum tersedia.

Kategori:
BenzopyransCarbohydratesChromones +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetacillin Approved DB00739
small molecule | CAS: 3511-16-8

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of ant…

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +8
Target Protein:
Penicillin-binding protein 2aPenicillin-binding protein 1bPenicillin-binding protein 3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetrombopag DB16184
small molecule | CAS: 1257792-41-8

Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).

Kategori:
HydrazinesPyrazoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexachlorophene Approved DB00756
small molecule | CAS: 70-30-4

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorder…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +8
Target Protein:
D-lactate dehydrogenaseSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialGlutamate dehydrogenase 1, mitochondrial +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexadecanal DB03381
small molecule | CAS: 629-80-1

Deskripsi belum tersedia.

Target Protein:
RhodopsinAcyl-CoA-binding protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 86855-26-7

Deskripsi belum tersedia.

Kategori:
Fatty AcidsLipidsPalmitic Acids +1
Target Protein:
Palmitoyl-protein thioesterase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29710-31-4

Deskripsi belum tersedia.

Target Protein:
HTH-type transcriptional regulator EthR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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