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13591

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Halaman 138 / 272
biotech

Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).

Kategori:
Amino Acids, Peptides, and ProteinsAnalgesicsAnalgesics, Non-Narcotic +12
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biotech

Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
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biotech | CAS: 183623-03-2

Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).

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biotech

Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner …

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biotech

Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
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biotech

Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsCancer immunotherapy +9
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biotech

Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
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biotech

Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 5…

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
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biotech

Deskripsi belum tersedia.

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biotech

Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +10
Waktu ParuhThe mean half-life …
Vol. DistribusiThe volume of distr…
KlirensReadily accessible …
Genetik -
biotech

Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma vi…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBiological Products +13
Waktu ParuhHuman Varicella-Zos…
Vol. DistribusiFollowing intraveno…
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Huperzine B DB03348
small molecule | CAS: 103548-82-9

Huperzine B is a novel acetylcholinesterase inhibitor.

Kategori:
Drugs, Chinese HerbalPlant Extracts
Target Protein:
Acetylcholinesterase
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HX-1171 DB12162
small molecule | CAS: 148081-72-5

Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety, Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects).

Kategori:
Benzene DerivativesPhenols
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HY-111996 DB16964
small molecule | CAS: 1380696-64-9

Deskripsi belum tersedia.

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Hyaluronic acid Approved DB08818
small molecule | CAS: 9004-61-9

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluron…

Kategori:
Adjuvants, ImmunologicBiocompatible MaterialsCarbohydrates +16
Target Protein:
CD44 antigenIntercellular adhesion molecule 1Hyaluronan mediated motility receptor +12
Waktu ParuhWhen injected by th…
Vol. DistribusiThere is limited in…
KlirensThere is limited in…
Genetik -
small molecule | CAS: 9004-61-9

Hyaluronic acid (non-animal stabilized) is under investigation in clinical trial NCT03460158 (Prospective Evaluation of Facial Cosmetic Procedures).

Kategori:
CarbohydratesGlycosaminoglycansPolysaccharides
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Hyaluronidase Approved DB14740
biotech | CAS: 9001-54-1

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.[L13338] The action of hyaluronidase was first described in 1936, and named in 1939.[A199026] Early research into hyaluron…

Kategori:
Blood and Blood Forming OrgansCarbon-Oxygen LyasesEnzymes +6
Target Protein:
Hyaluronic acidTransforming growth factor beta-1 proprotein
Waktu ParuhHyaluronidase has a…
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
biotech | CAS: 757971-58-7

A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragmen…

Kategori:
Blood and Blood Forming OrgansCarbon-Oxygen LyasesEnzymes +6
Target Protein:
Hyaluronic acidTransforming growth factor beta-1 proprotein
Waktu ParuhHyaluronidase has a…
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
Hyaluronidase (ovine) Approved DB00070
biotech | CAS: 488712-31-8

Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.

Kategori:
EnzymesEnzymes and CoenzymesGlycoside Hydrolases
Target Protein:
Transforming growth factor beta-1 proprotein
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Hycanthone DB14061
small molecule | CAS: 3105-97-3

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

Kategori:
AnthelminticsAnti-Infective AgentsAntiparasitic Agents +7
Target Protein:
ATP-dependent translocase ABCB1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Adenylosuccinate synthetaseAdenylosuccinate synthetase
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Hydracarbazine DB09243
small molecule | CAS: 3614-47-9

Hydracarbazine is a pyridazine that has found use as an antihypertensive agent [A19790] It was once marketed in France under the tradename Normatensyl.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAntidepressive Agents +3
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small molecule | CAS: 503-66-2

Deskripsi belum tersedia.

Kategori:
Hydroxy AcidsIsomerismLactates
Target Protein:
Pimeloyl-[acyl-carrier protein] methyl ester esterase
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Hydralazine Approved DB01275
small molecule | CAS: 86-54-4

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.[A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and onl…

Kategori:
Antihypertensive AgentsAntihypertensive Agents Indicated for HypertensionArteriolar Smooth Muscle, Agents Acting On +15
Target Protein:
Amine oxidase [copper-containing] 3Hypoxia-inducible factor 1-alphaProlyl 4-hydroxylase subunit alpha-1
Waktu ParuhHydralazine has a h…
Vol. DistribusiThe volume of distr…
KlirensThe majority of hyd…
Genetik -
Hydrastine DB19354
small molecule | CAS: 118-08-1

Deskripsi belum tersedia.

Kategori:
AlkaloidsHeterocyclic Compounds, Fused-RingHydrastis +1
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Hydrastinine DB19359
small molecule | CAS: 6592-85-4

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIsoquinolines
Waktu Paruh-
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Genetik -
small molecule | CAS: 7647-01-0

Deskripsi belum tersedia.

Kategori:
Acid PreparationsAcidsAcids, Noncarboxylic +7
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Hydrochlorothiazide Approved DB00999
small molecule | CAS: 58-93-5

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic.[A185138] It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.[A18513…

Kategori:
AmidesAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension +25
Target Protein:
Solute carrier family 12 member 3Angiotensin-converting enzymeCalcium-activated potassium channel subunit alpha-1
Waktu ParuhThe plasma half lif…
Vol. DistribusiThe volume of distr…
KlirensThe renal clearance…
Genetik -
Hydrocodone Approved DB00956
small molecule | CAS: 125-29-1

Hydrocodone is a synthetic opioid derivative of codeine.[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced b…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +23
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorSigma non-opioid intracellular receptor 1
Waktu ParuhThe half-life of el…
Vol. DistribusiThe apparent volume…
KlirensOfficial FDA labeli…
Genetik -
Hydrocortisone Approved DB00741
small molecule | CAS: 50-23-7

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendal…

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +55
Target Protein:
Glucocorticoid receptorAnnexin A1
Waktu ParuhTotal hydrocortison…
Vol. DistribusiTotal hydrocortison…
KlirensTotal hydrocortison…
Genetik -
small molecule | CAS: 74050-20-7

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +25
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
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Genetik -
Hydrocortisone acetate Approved DB14539
small molecule | CAS: 50-03-3

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +24
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Hydrocortisone butyrate Approved DB14540
small molecule | CAS: 13609-67-1

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdministration, Topical +26
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Hydrocortisone phosphate Approved DB14542
small molecule | CAS: 3863-59-0

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +18
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Hydrocortisone probutate Approved DB14543
small molecule | CAS: 72590-77-3

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +26
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
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Genetik -
Hydrocortisone succinate Approved DB14545
small molecule | CAS: 2203-97-6

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +22
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Hydroflumethiazide Approved DB00774
small molecule | CAS: 135-09-1

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)

Kategori:
AmidesAntihypertensive AgentsBenzothiadiazines +19
Target Protein:
Solute carrier family 12 member 1Carbonic anhydrase 7Carbonic anhydrase 9 +6
Waktu ParuhIt appears to have …
Vol. Distribusi-
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Hydrogen DB15127
small molecule | CAS: 1333-74-0

Hydrogen is under investigation in clinical trial NCT02830854 (Molecular Hydrogen for Cognitive Function and Performance in Elderly).

Kategori:
ElementsGases
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Hydrogen fluoride Approved DB11072
small molecule | CAS: 7664-39-3

Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as [DB00472] (Prozac). It is used as a chemical reagent in several industrial processes such as oil refinery. It is also …

Kategori:
AcidsAcids, NoncarboxylicDental Agents +1
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Hydrogen iodide DB15778
small molecule | CAS: 10034-85-2

Deskripsi belum tersedia.

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Hydrogen peroxide Approved DB11091
small molecule | CAS: 7722-84-1

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it…

Kategori:
Alimentary Tract and MetabolismAnionsAnti-Infective Agents +19
Target Protein:
Tyrosine-protein phosphatase non-receptor type 1
Waktu Paruh-
Vol. DistribusiTarget organs affec…
Klirens-
Genetik -
biotech | CAS: 84836-98-6

Hydrogenated coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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biotech | CAS: 8016-70-4

Extracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. According to the FDA, hydrogenated soybean oil is generally recognized as safe (G…

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small molecule | CAS: 23599-55-5

Deskripsi belum tersedia.

Kategori:
Biological FactorsHeterocyclic Compounds, Fused-RingPigments, Biological +1
Target Protein:
Precorrin-8X methylmutase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 1236208-20-0

Deskripsi belum tersedia.

Kategori:
Antipsychotic AgentsCentral Nervous System DepressantsHeterocyclic Compounds, Fused-Ring +2
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Hydromorphinol DB01512
small molecule | CAS: 2183-56-4

Deskripsi belum tersedia.

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