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12560

Total database: 17430
Struktur (SMILES)
9109 (72.5%)
Target
6912 (55.0%)
Genomik
109 (0.9%)
Referensi
12560 (100.0%)

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Hasil Pencarian (12560)

Halaman 137 / 252
Iobenguane Approved DB06704
small molecule | CAS: 80663-95-2

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionu…

Kategori:
AmidinesBenzene DerivativesCompounds used in a research, industrial, or household setting +16
Target Protein:
Sodium-dependent noradrenaline transporter
Waktu ParuhPhysical half life …
Vol. Distribusi-
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Genetik -
Iobenguane sulfate I-123 Approved DB09546
small molecule | CAS: 80663-95-2

Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].

Kategori:
Drugs that are Mainly Renally ExcretedRadioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Iobenzamic acid DB13428
small molecule | CAS: 3115-05-7

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +7
Waktu Paruh-
Vol. Distribusi-
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Iobitridol Approved DB12407
small molecule | CAS: 136949-58-1

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iocarmic acid DB13755
small molecule | CAS: 10397-75-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodamide DB08948
small molecule | CAS: 440-58-4

Iodamide is a contrast medium molecule that is no longer marketed in the United States.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Iodide Approved DB12754
small molecule | CAS: 20461-54-5

Iodide has been investigated for the treatment of Goiter, Nodular.

Kategori:
AnionsElectrolytesIodides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodide I-123 Approved DB09420
small molecule | CAS: 69239-56-1

Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid g…

Kategori:
Diagnostic RadiopharmaceuticalsElementsHalogens +6
Waktu ParuhIodine-123 decays b…
Vol. Distribusi-
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Iodine Approved DB05382
small molecule | CAS: 7553-56-2

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A1921…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +12
Target Protein:
Sodium/iodide cotransporterMicrobial proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 56897-09-7

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesDiagnostic Radiopharmaceuticals +6
Waktu Paruh-
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biotech | CAS: 2420475-06-3

Deskripsi belum tersedia.

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Iodine I-125 DB14804
small molecule | CAS: 14158-31-7

Iodine I-125 is under investigation in clinical trial NCT00079417 (Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma).

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biotech | CAS: 1000874-23-6

Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

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Iodine povacrylex Approved DB09537
small molecule | CAS: 845736-10-9

Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity. DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the prepara…

Kategori:
Anti-Infective Agents, Local
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
Iodixanol Approved DB01249
small molecule | CAS: 92339-11-2

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu Paruh2.1 hours. In patie…
Vol. Distribusi* 0.26 L/kg
Klirens-
Genetik -
Iodobenzene DB02252
small molecule | CAS: 591-50-4

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated
Target Protein:
Endoglucanase F
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 123748-56-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodoform Approved DB13813
small molecule | CAS: 75-47-8

Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions [A32890]. Due to its antimicrobial properties following topi…

Kategori:
DermatologicalsHydrocarbons, HalogenatedMedicated Dressings +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Iodohippurate sodium I-123 Approved DB09448
small molecule | CAS: 56254-07-0

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsRenal System
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 147-58-0

Iodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults).

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +7
Waktu Paruh-
Vol. Distribusi-
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small molecule | CAS: 55406-53-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAllergensAntigens +1
Waktu Paruh-
Vol. Distribusi-
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Iodoxamic acid DB13539
small molecule | CAS: 31127-82-9

Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
Waktu Paruh-
Vol. Distribusi-
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Iofetamine I-123 Approved DB09480
small molecule | CAS: 75917-92-9

Deskripsi belum tersedia.

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +13
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 1214283-52-9

Deskripsi belum tersedia.

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Ioflupane F-18 DB16913
small molecule | CAS: 186381-69-1

Deskripsi belum tersedia.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
Waktu Paruh-
Vol. Distribusi-
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Ioflupane I-123 Approved DB08824
small molecule | CAS: 155798-07-5

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +9
Target Protein:
Sodium-dependent dopamine transporter
Waktu ParuhHalf life is 13.2 h…
Vol. DistribusiCompared to the ent…
Klirens-
Genetik -
small molecule | CAS: 949575-24-0

Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

Kategori:
AmidesAmino AcidsAmino Acids, Acidic +2
Target Protein:
Glutamate carboxypeptidase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ioforminol DB12439
small molecule | CAS: 1095110-48-7

Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.

Kategori:
Acids, AcyclicAcids, CarbocyclicAmides +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Ioglicic acid DB13701
small molecule | CAS: 49755-67-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ioglycamic acid DB13741
small molecule | CAS: 2618-25-9

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iohexol Approved DB01362
small molecule | CAS: 66108-95-0

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmo…

Kategori:
Acids, CarbocyclicAgents that reduce seizure thresholdBenzene Derivatives +12
Waktu ParuhIntrathecal half-li…
Vol. Distribusi* 350-849 mL/kg
Klirens* 109 mL/min [Adult…
Genetik -
Iomazenil DB14971
small molecule | CAS: 127985-21-1

Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).

Kategori:
BenzazepinesBenzodiazepinonesHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
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Iomeprol Approved DB11705
small molecule | CAS: 78649-41-9

Iomeprol has been investigated for the diagnostic of Coronary Artery Disease.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
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ION356 DB19389
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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ION582 DB18158
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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IONIS-HBVRx DB16202
biotech | CAS: 1403787-62-1

IONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).

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Iophendylate Approved DB01187
small molecule | CAS: 99-79-6

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iopodic acid Approved DB09333
small molecule | CAS: 5587-89-3

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6.[A32080] Due to its particular structure, it presents a hi…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Target Protein:
Thyroxine 5-deiodinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 873438-88-1

Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).

Kategori:
AlcoholsBenzene DerivativesEthers +12
Waktu Paruh-
Vol. Distribusi-
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Iopromide Approved DB09156
small molecule | CAS: 73334-07-3

Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures …

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +8
Waktu ParuhAfter intravenous a…
Vol. DistribusiThe total volume of…
KlirensThe mean total and …
Genetik -
Iopydol DB13389
small molecule | CAS: 5579-92-0

Deskripsi belum tersedia.

Kategori:
Contrast MediaNon-Watersoluble X-Ray Contrast MediaX-Ray Contrast Media, Iodinated
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 9062-07-1

iota-Carrageenan is under investigation in clinical trial NCT01944631 (Iota-Carrageenan Nasal Spray in Common Cold).

Kategori:
CarbohydratesPolysaccharides
Waktu Paruh-
Vol. Distribusi-
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Iothalamic acid Approved DB09133
small molecule | CAS: 2276-90-6

Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +16
Waktu ParuhIn patients with no…
Vol. Distribusi-
Klirens-
Genetik -
Iotroxic acid DB08945
small molecule | CAS: 51022-74-3

Iotroxic acid is a contrast medium molecule.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Ioversol Approved DB09134
small molecule | CAS: 87771-40-2

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.[L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays.[L4…

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu ParuhThe elimination hal…
Vol. DistribusiIn adults, the volu…
KlirensIn healthy voluntee…
Genetik -
IOWH-032 DB12959
small molecule | CAS: 1191252-49-9

Iowh032 has been investigated for the treatment of Cholera, Diarrhea, and Secretory Diarrhea.

Kategori:
Oxazoles
Target Protein:
Cystic fibrosis transmembrane conductance regulator
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Ioxaglic acid Approved DB09313
small molecule | CAS: 59017-64-0

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance …

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Waktu ParuhHexabrix 320 is rap…
Vol. DistribusiIoxaglate salts cro…
Klirens245 ml/kg [L1886]
Genetik -
Ioxilan Approved DB09135
small molecule | CAS: 107793-72-6

Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant …

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu ParuhAn initial fast dis…
Vol. DistribusiIoxilan is distribu…
KlirensThe total clearance…
Genetik -
Ioxitalamic acid Approved DB13444
small molecule | CAS: 28179-44-4

Ioxitalamate is an ionic iodinated contrast medium.[A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.[A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Lie…

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +12
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe total clearance…
Genetik -
IP501 DB06450
small molecule

IP-501 is an investigational antifibrotic compound being tested for the treatment of alcohol-induced liver disease and chronic hepatitis-C-induced cirrhosis. The compound was developed by Indevus Pharmaceuticals.

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Menampilkan 6801–6850 dari 12560
Sebelumnya Halaman 137 / 252 Berikutnya