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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 137 / 282
small molecule

Deskripsi belum tersedia.

Kategori:
Amino SugarsCarbohydratesHexosamines +2
Target Protein:
Ferrichrome-iron receptor
Waktu Paruh-
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Genetik -
small molecule | CAS: 3616-42-0

Deskripsi belum tersedia.

Kategori:
Amino SugarsCarbohydratesGlucosephosphates +3
Target Protein:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]N-acetylglucosamine-6-phosphate deacetylase
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Glucose oxidase DB12862
biotech | CAS: 9001-37-0

Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.

Kategori:
Alcohol OxidoreductasesEnzymesEnzymes and Coenzymes +1
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small molecule | CAS: 56-73-5

An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)

Kategori:
CarbohydratesGlucosephosphatesHexosephosphates +1
Target Protein:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]Glucose-6-phosphate isomerase
Waktu Paruh-
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Glufosfamide DB06177
small molecule | CAS: 132682-98-5

Deskripsi belum tersedia.

Kategori:
CarbohydratesHexosesHydrocarbons, Halogenated +7
Waktu Paruh-
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Glumetinib DB15630
small molecule | CAS: 1642581-63-2

Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).

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Glutamic acid Approved DB00142
small molecule | CAS: 56-86-0

A peptide that is a homopolymer of glutamic acid.

Kategori:
Acid PreparationsAlimentary Tract and MetabolismAmino Acids +11
Target Protein:
Metabotropic glutamate receptor 1Metabotropic glutamate receptor 4Glutamate receptor ionotropic, kainate 4 +59
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small molecule | CAS: 80143-57-3

Glutamine 2-n-15 is under investigation in clinical trial NCT01912235 (Arginine Synthesis in Healthy Adult Humans).

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small molecule | CAS: 1955-67-5

Deskripsi belum tersedia.

Kategori:
AminesAmino AcidsAmino Acids, Acidic +5
Target Protein:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
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Glutaral DB03266
small molecule | CAS: 111-30-8

One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.

Kategori:
AldehydesAnti-Infective AgentsCompounds used in a research, industrial, or household setting +5
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Glutathione disulfide Approved DB03310
small molecule | CAS: 27025-41-8

A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Glutathione peroxidaseMicrosomal glutathione S-transferase 1Glutathione S-transferases (Cytosolic) +2
Waktu Paruh-
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small molecule | CAS: 24429-05-8

Deskripsi belum tersedia.

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small molecule | CAS: 33932-35-3

Deskripsi belum tersedia.

Kategori:
AminesAmino Acids, Peptides, and ProteinsBiogenic Amines +4
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glutathione reductase, mitochondrial
Waktu Paruh-
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Glutazumab DB16697
biotech

Glutazumab is a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein exerting anti-diabetic effects.[A235745]

Kategori:
Blood Glucose Lowering Agents
Target Protein:
Glucagon-like peptide 1 receptor
Waktu Paruh-
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Glutethimide Approved DB01437
small molecule | CAS: 77-21-4

Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.

Kategori:
Central Nervous System AgentsCentral Nervous System DepressantsHypnotics and Sedatives +5
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Cytochrome P450 2D6GABA(A) Receptor
Waktu Paruh10-12 hours
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Glyburide Approved DB01016
small molecule | CAS: 10238-21-8

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II.[L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin].[L8123] Glyburide stimulates insulin secretio…

Kategori:
Alimentary Tract and MetabolismAmidesBCRP/ABCG2 Substrates +28
Target Protein:
ATP-binding cassette sub-family C member 8Sulfonylurea receptor 1, Kir6.2ATP-binding cassette sub-family C member 9 +6
Waktu ParuhElderly patients ha…
Vol. DistribusiElderly patients ha…
KlirensElderly patients ha…
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Aldehyde OxidoreductasesEnzymesEnzymes and Coenzymes +3
Waktu Paruh-
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Glycerin Approved DB09462
small molecule | CAS: 56-81-5

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

Kategori:
AlcoholsAlimentary Tract and MetabolismBasic Ointments and Protectants +21
Target Protein:
Peroxisome proliferator-activated receptor deltaGroup IIE secretory phospholipase A2Inositol-3-phosphate synthase 1 +11
Waktu Paruh30 - 45 minutes
Vol. DistribusiGlycerin is distrib…
Klirens-
Genetik -
small molecule | CAS: 17181-54-3

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesLipids +5
Target Protein:
Triosephosphate isomerase
Waktu Paruh-
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Glycerol phenylbutyrate Approved DB08909
small molecule | CAS: 611168-24-2

Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

Kategori:
Acids, CarbocyclicAlcoholsAlimentary Tract and Metabolism +14
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Genetik -
small molecule | CAS: 614-33-5

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene Derivatives
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Genetik -
small molecule | CAS: 111-03-5

Deskripsi belum tersedia.

Kategori:
Lipids
Target Protein:
Glucose-dependent insulinotropic receptor
Waktu Paruh-
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Genetik -
small molecule | CAS: 27215-38-9

Deskripsi belum tersedia.

Kategori:
Cariostatic AgentsCompounds used in a research, industrial, or household settingFatty Acids +5
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Glyceryl monocaprylate Approved DB19362
small molecule | CAS: 26402-26-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsLipids +1
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small molecule | CAS: 31566-31-1

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.

Kategori:
Lipids
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small molecule | CAS: 2752-99-0

Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.

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small molecule | CAS: 122-32-7

Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

Kategori:
FatsFats, UnsaturatedGlycerides +2
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsNucleic Acids, Nucleotides, and Nucleosides +1
Target Protein:
Phosphoribosylglycinamide formyltransferase 2Phosphoribosylglycinamide formyltransferaseTrifunctional purine biosynthetic protein adenosine-3
Waktu Paruh-
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small molecule | CAS: 640-79-9

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +12
Target Protein:
7-alpha-hydroxysteroid dehydrogenase
Waktu Paruh-
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small molecule | CAS: 475-31-0

The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +11
Target Protein:
Gastrotropin
Waktu Paruh-
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Glycocyamine DB02751
small molecule | CAS: 352-97-6

Deskripsi belum tersedia.

Kategori:
Affinity LabelsAmino AcidsAmino Acids, Peptides, and Proteins +3
Target Protein:
Guanidinoacetate N-methyltransferase
Waktu Paruh-
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Glycol salicylate Approved DB11323
small molecule | CAS: 87-28-5

Glycol salicylate, also known as _2-hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic …

Kategori:
Acids, CarbocyclicAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-Steroidal +5
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu ParuhThe serum half-life…
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Glycolic acid Approved DB03085
small molecule | CAS: 79-14-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicDermatologicals +2
Target Protein:
Glucose-6-phosphate 1-dehydrogenase
Waktu Paruh-
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GlycoPEG-GCSF DB06022
biotech

GlycoPEG-GCSF is a long-acting GlycoPEGylated granulocyte colony stimulating factor for the treatment of chemotherapy-induced neutropenia.

Kategori:
Pegylated agents
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Glycopyrronium Approved DB00986
small molecule | CAS: 740028-90-4

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.[L33110] It is one of the most commonly prescribed anticholinergic medi…

Kategori:
Adjuvants, AnesthesiaAdrenergics, InhalantsAgents producing tachycardia +30
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2 +2
Waktu ParuhThe half life after…
Vol. DistribusiThe mean volume of …
KlirensA 6 µg/kg intraveno…
Genetik -
Glycovir DB13106
small molecule | CAS: 131262-82-3

Glycovir has been used in trials studying the treatment of HIV Infections.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Target Protein:
Maltase-glucoamylase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
D-alanyl-D-alanine carboxypeptidase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
D-alanyl-D-alanine carboxypeptidase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prolyl tripeptidyl peptidase
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Glycyrrhiza glabra Approved DB14312
biotech | CAS: 84775-66-6

Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsBiological ProductsCell-mediated Immunity +12
Waktu Paruh-
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Glycyrrhizic acid Approved DB13751
small molecule | CAS: 1405-86-3

Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_.[F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it ca…

Kategori:
Alimentary Tract and MetabolismAnti-Inflammatory AgentsBile and Liver Therapy +6
Target Protein:
11-beta-hydroxysteroid dehydrogenase 1Tumor necrosis factorCaspase-3 +2
Waktu ParuhDepending on the do…
Vol. DistribusiThe apparent volume…
KlirensThe constant reabso…
Genetik -
Glymidine Approved DB01382
small molecule | CAS: 339-44-6

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be depende…

Kategori:
Alimentary Tract and MetabolismAmidesBlood Glucose Lowering Agents +7
Target Protein:
ATP-sensitive inward rectifier potassium channel 1ATP-sensitive inward rectifier potassium channel 10ATP-binding cassette sub-family C member 8
Waktu Paruh4 hours.
Vol. Distribusi-
Klirens-
Genetik -
Glyoxylic acid DB04343
small molecule | CAS: 298-12-4

Deskripsi belum tersedia.

Kategori:
Acids, Aldehydic
Target Protein:
Malate synthase GIsocitrate lyaseMalate synthase G +1
Waktu Paruh-
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Glypromate DB05633
small molecule | CAS: 32302-76-4

Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by …

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
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GMA-161 DB15397
biotech | CAS: 946415-70-9

GMA-161 is under investigation in clinical trial NCT00244257 (Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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GMI-1359 DB18092
biotech

GMI-1359 is a small molecule, glycomimetic compound with dual inhibitory activity against E-selectin and CXCR4.[A261406]

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GMK DB06661
biotech

GMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma

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GMX1777 DB05217
small molecule

GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact me…

Kategori:
Amidines
Target Protein:
Nicotinamide phosphoribosyltransferase
Waktu Paruh-
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GO-203-2C DB15008
small molecule | CAS: 1469735-88-3

GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).

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