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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (13591)

Halaman 136 / 272
biotech

Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heparin Approved DB01109
small molecule | CAS: 9005-49-6

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III …

Kategori:
Agents causing hyperkalemiaAnticoagulantsAntivaricose Therapy +16
Target Protein:
Antithrombin-IIICoagulation factor XP-selectin +9
Waktu ParuhThe plasma half-lif…
Vol. DistribusiThe volume of distr…
KlirensThe clearance in ad…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
C-C motif chemokine 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
C-C motif chemokine 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hepatitis A Vaccine Approved DB10989
biotech

Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure.[A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has bee…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +4
Target Protein:
B-lymphocytes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsAntigens +19
Waktu ParuhEvaluation of pharm…
Vol. DistribusiEvaluation of pharm…
KlirensEvaluation of pharm…
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsGlobulins +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hepcidin-25 DB19226
biotech | CAS: 1356390-47-0

Hepcidin-25 is under investigation in clinical trial NCT03381833 (A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-dependent Beta Thalassemia).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HEPES DB16872
small molecule | CAS: 7365-45-9

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsBuffers +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptabarbital DB01354
small molecule | CAS: 509-86-4

Heptabarbital is an intermediate or short term barbiturate used mainly for sedation and hypnosis.

Kategori:
Anticholinergic AgentsBarbiturates, PlainCentral Nervous System Depressants +6
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5617-32-3

Deskripsi belum tersedia.

Kategori:
Pegylated agents
Target Protein:
Carbonyl reductase [NADPH] 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptaminol DB13574
small molecule | CAS: 372-66-7

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsLipids
Target Protein:
RhodopsinFimbrial proteinFe(3+) dicitrate transport protein FecA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptanoic acid DB02938
small molecule | CAS: 111-14-8

Deskripsi belum tersedia.

Target Protein:
Phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 78617-12-6

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1APeroxisome proliferator-activated receptor delta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hesperetin DB01094
small molecule | CAS: 520-33-2

Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.

Kategori:
BCRP/ABCG2 InhibitorsBenzopyransCarbohydrates +8
Target Protein:
Diacylglycerol O-acyltransferase 1Microsomal triglyceride transfer protein large subunitSterol O-acyltransferase 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hesperidin Approved DB04703
small molecule | CAS: 520-26-3

Hesperidin is a flavan-on glycoside found in citrus fruits.

Kategori:
BenzopyransCarbohydratesChromones +5
Target Protein:
Voltage-dependent N-type calcium channel subunit alpha-1BAurora kinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24292-52-2

Deskripsi belum tersedia.

Kategori:
BenzopyransCarbohydratesChromones +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetacillin Approved DB00739
small molecule | CAS: 3511-16-8

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of ant…

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +8
Target Protein:
Penicillin-binding protein 2aPenicillin-binding protein 1bPenicillin-binding protein 3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heterotheca inuloides flower Approved DB14331
biotech

Heterotheca inuloides flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetrombopag DB16184
small molecule | CAS: 1257792-41-8

Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).

Kategori:
HydrazinesPyrazoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexachlorophene Approved DB00756
small molecule | CAS: 70-30-4

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorder…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +8
Target Protein:
D-lactate dehydrogenaseSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialGlutamate dehydrogenase 1, mitochondrial +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexadecanal DB03381
small molecule | CAS: 629-80-1

Deskripsi belum tersedia.

Target Protein:
RhodopsinAcyl-CoA-binding protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 86855-26-7

Deskripsi belum tersedia.

Kategori:
Fatty AcidsLipidsPalmitic Acids +1
Target Protein:
Palmitoyl-protein thioesterase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29710-31-4

Deskripsi belum tersedia.

Target Protein:
HTH-type transcriptional regulator EthR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 124-09-4

Deskripsi belum tersedia.

Kategori:
AminesAmphetaminesEthylamines +3
Target Protein:
Carbonic anhydrase 4Carbonic anhydrase 1Carbonic anhydrase 6 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexamidine Approved DB03808
small molecule | CAS: 3811-75-4

Deskripsi belum tersedia.

Kategori:
AmidinesAnti-Infective AgentsAnti-Infective Agents, Local +8
Target Protein:
HTH-type transcriptional regulator QacRHTH-type transcriptional regulator QacR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexanoyl-CoA DB02563
small molecule | CAS: 5060-32-2

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
Enoyl-CoA hydratase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexapeptide-2 DB18238
biotech | CAS: 87616-84-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsGrowth Hormone-Releasing HormonePeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexapropymate DB13662
small molecule | CAS: 358-52-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCentral Nervous System DepressantsHypnotics and Sedatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34367-89-0

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesInositol Phosphates +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexestrol DB07931
small molecule | CAS: 84-16-2

A synthetic estrogen that has been used as a hormonal antineoplastic agent.

Kategori:
Antineoplastic AgentsAntineoplastic Agents, HormonalBenzene Derivatives +11
Target Protein:
Aldo-keto reductase family 1 member C1Estrogen receptorNuclear receptor subfamily 1 group I member 2 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexobarbital DB01355
small molecule | CAS: 56-29-1

A barbiturate that is effective as a hypnotic and sedative.

Kategori:
AdjuvantsAnestheticsAnesthetics, General +18
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-4 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexobendine Approved DB13265
small molecule | CAS: 54-03-5

Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478].

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexocyclium Approved DB06787
small molecule | CAS: 6004-98-4

Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. Proton pump inhibitors lik…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAnticholinergic Agents +3
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexoprenaline DB08957
small molecule | CAS: 3215-70-1

Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +18
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexylcaine Approved DB00473
small molecule | CAS: 532-77-4

Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mout…

Kategori:
AminesCyclohexanesCycloparaffins
Target Protein:
Sodium channel protein type 5 subunit alphaSodium channel protein type 10 subunit alpha
Waktu Paruh<10 minutes
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexylresorcinol Approved DB11254
small molecule | CAS: 136-77-6

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid …

Kategori:
AnthelminticsAnti-Infective AgentsAnti-Infective Agents, Local +6
Target Protein:
TyrosinaseDNA topoisomerase 1Protein-glutamine gamma-glutamyltransferase 2
Waktu ParuhReadily accessible …
Vol. DistribusiReadily accessible …
KlirensReadily accessible …
Genetik -
HGTV-43 DB05807
biotech

HGTV43 is an anti-sense treatment designed to produce T cells that are genetically resistant to HIV infection. HGTV43 is one of a number of so-called 'gene transfer vectors' developed by the biotechnology company Enzo Biochem, Inc.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hidrosmin DB13490
small molecule | CAS: 115960-14-0

Deskripsi belum tersedia.

Kategori:
BenzopyransCapillary Stabilizing AgentsChromones +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Higenamine DB12779
small molecule | CAS: 5843-65-2

Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-Agonists +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hiltonol DB17293
biotech | CAS: 59789-29-6

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAmino AcidsAmino Acids, Basic +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hispidulin DB14008
small molecule | CAS: 1447-88-7

Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties [A32513].

Kategori:
BenzopyransChromonesFlavonoids +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histamine Approved DB05381
small molecule | CAS: 51-45-6

A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Kategori:
Adjuvants, ImmunologicAminesAntineoplastic and Immunomodulating Agents +19
Target Protein:
Histamine H1 receptorHistamine H2 receptorHistamine H3 receptor +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1464897-15-1

Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).

Kategori:
AminesAnti-Asthmatic AgentsAutacoids +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histapyrrodine DB13479
small molecule | CAS: 493-80-1

Deskripsi belum tersedia.

Kategori:
Antihistamines for Systemic UseSubstituted Ethylene Diamines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histidine DB00117
small molecule | CAS: 71-00-1

An essential amino acid that is required for the production of histamine.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Essential +4
Target Protein:
Histidine decarboxylaseHistidine--tRNA ligase, cytoplasmicSodium-coupled neutral amino acid transporter 3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6751–6800 dari 13591
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