Digital Pharmacy - Dashboard Peneliti

GW-274150 DB12237

small molecule | CAS: 210354-22-6

GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid.

Kategori:

AnionsElectrolytesHydrogen Sulfide +3

Target Protein:

Nitric oxide synthase, inducible

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GW-3965 DB03791

small molecule | CAS: 405911-09-3

GW-3965 is a liver X receptor ligand.

Kategori:

Acids, CarbocyclicAminesBenzene Derivatives +2

Target Protein:

Oxysterols receptor LXR-betaOxysterols receptor LXR-alpha

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GW-406381 DB12009

small molecule | CAS: 221148-46-5

GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.

Target Protein:

Prostaglandin G/H synthase 2

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GW-493838 DB12760

small molecule | CAS: 253124-46-8

GW493838 has been used in trials studying the treatment of Neuropathic Pain.

Target Protein:

Adenosine receptor A1

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GW-590735 DB07215

small molecule | CAS: 343321-96-0

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicFatty AcidsFatty Acids, Volatile +2

Target Protein:

Nuclear receptor coactivator 1Peroxisome proliferator-activated receptor alpha

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GW-813893 DB07278

small molecule | CAS: 478644-12-1

Deskripsi belum tersedia.

Kategori:

AmidesAnticoagulantsAntithrombins +8

Target Protein:

Coagulation factor XProthrombin

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GW-870086 DB12322

small molecule | CAS: 827319-43-7

GW870086X has been investigated for the treatment of ASTHMA.

Kategori:

Fused-Ring Compounds

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GW810781 DB16032

small molecule | CAS: 280571-30-4

GW810781 is under investigation in clinical trial NCT00046332 (A Study Comparing 4 Doses of GW810781 Versus Placebo in Hiv-infected Patients).

Kategori:

Anti-HIV Agents

Target Protein:

Gag-Pol polyprotein

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GW842166 DB11903

small molecule | CAS: 666260-75-9

GW842166X has been used in trials studying the treatment of Pain, Analgesia, Inflammation, Osteoarthritis, and Pain, Inflammatory, among others.

Kategori:

Agents producing tachycardiaCannabinoid Receptor AgonistsCannabinoids and similars +1

Target Protein:

Cannabinoid receptor 2

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GXC-301 DB18831

biotech

Deskripsi belum tersedia.

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GYM329 DB18590

biotech

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner

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GZ-389988 DB16056

small molecule | CAS: 1788906-96-6

GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee).

Target Protein:

NT-3 growth factor receptorHigh affinity nerve growth factor receptorBDNF/NT-3 growth factors receptor

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H-89 DB07995

small molecule | CAS: 127243-85-0

Deskripsi belum tersedia.

Kategori:

AmidesEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +3

Target Protein:

cAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase inhibitor alphaSerine/threonine-protein kinase haspin +1

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H3B-6527 DB15169

small molecule | CAS: 1702259-66-2

H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).

Kategori:

Heterocyclic Compounds, Fused-Ring

Target Protein:

Fibroblast growth factor receptor 4

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H3B-8800 DB14017

small molecule | CAS: 1825302-42-8

H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551]. It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferent…

Target Protein:

Splicing factor 3B subunit 1

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Hachimycin DB13302

small molecule | CAS: 1394-02-1

Deskripsi belum tersedia.

Kategori:

Anti-Infective AgentsAntifungals for Dermatological UseAntifungals for Topical Use +6

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Hadacidin DB02109

small molecule | CAS: 689-13-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Peptides, and ProteinsAntibiotics, Antineoplastic +4

Target Protein:

Inosine-5'-monophosphate dehydrogenase 1Adenylosuccinate synthetaseAdenylosuccinate synthetase +1

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Haemagglutinin-strain A(H3N2) Approved DB15475

biotech

Deskripsi belum tersedia.

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Haemagglutinin-strain B (Victoria-like) Approved DB15473

biotech

Deskripsi belum tersedia.

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Haematonectria haematococca Approved DB10934

biotech

Haematonectria haematococca is a fungus which can provoke allergic reactions. Haematonectria haematococca extract is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

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Haemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigen Approved DB10342

biotech

Haemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigen is a vaccine containing outer membrane antigen extracted from *Haemophilus influenzae*.

Kategori:

Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine

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Hafnium oxide DB17508

small molecule | CAS: 12055-23-1

Deskripsi belum tersedia.

Kategori:

AnionsElectrolytesElements +5

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Halazepam Approved DB00801

small molecule | CAS: 23092-17-3

Halazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam.[A1212] This drug is no longer marketed in the Unite…

Kategori:

Anti-Anxiety AgentsBenzazepinesBenzodiazepines and benzodiazepine derivatives +7

Target Protein:

Translocator proteinGABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site

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Halcinonide Approved DB06786

small molecule | CAS: 3093-35-4

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Labora…

Kategori:

Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +13

Target Protein:

Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1

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Haletazole DB15942

small molecule | CAS: 15599-36-7

Deskripsi belum tersedia.

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Halicin DB15624

small molecule | CAS: 40045-50-9

Deskripsi belum tersedia.

Kategori:

Sulfur CompoundsThiazoles

Target Protein:

c-Jun N-terminal kinases

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Halofantrine Approved DB01218

small molecule | CAS: 69756-53-2

Halofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poiso…

Kategori:

Agents that reduce seizure thresholdAnti-Infective AgentsAntimalarials +13

Target Protein:

Fe(II)-protoporphyrin IXCalmodulin-1Calmodulin-3 +3

Waktu Paruh6-10 days

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Halofuginone DB04866

small molecule | CAS: 55837-20-2

Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Bio…

Kategori:

Angiogenesis InhibitorsAngiogenesis Modulating AgentsAnti-Infective Agents +10

Target Protein:

Collagen alpha-1(I) chain72 kDa type IV collagenase

Waktu Paruh23.8 to 72.1 hours

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Halometasone DB13728

small molecule | CAS: 50629-82-8

Deskripsi belum tersedia.

Kategori:

Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroids +19

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Haloperidol Approved DB00502

small molecule | CAS: 52-86-8

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.[A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A274…

Kategori:

Agents that reduce seizure thresholdAnti-Dyskinesia AgentsAntidepressive Agents +50

Target Protein:

5-hydroxytryptamine receptor 2CD(2) dopamine receptor5-hydroxytryptamine receptor 2A +15

Waktu ParuhFollowing oral admi…

Vol. DistribusiThe apparent volume…

KlirensFollowing intraveno…

Genetik -

Haloprogin Approved DB00793

small molecule | CAS: 777-11-7

Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Com…

Kategori:

Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +5

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Haloxon DB11419

small molecule | CAS: 321-55-1

Deskripsi belum tersedia.

Kategori:

BenzopyransCoumarinsHeterocyclic Compounds, Fused-Ring +1

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Harmaline DB13875

small molecule | CAS: 304-21-2

Deskripsi belum tersedia.

Kategori:

Agents that produce hypertensionAgents that reduce seizure thresholdAlkaloids +14

Target Protein:

Histamine N-methyltransferase

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Harmine DB07919

small molecule | CAS: 442-51-3

Deskripsi belum tersedia.

Kategori:

AlkaloidsAntidepressive AgentsCarbolines +13

Target Protein:

Dual specificity tyrosine-phosphorylation-regulated kinase 2Dual specificity tyrosine-phosphorylation-regulated kinase 3Dual specificity tyrosine-phosphorylation-regulated kinase 1A +1

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Hawthorn leaf with flower DB15839

biotech

Deskripsi belum tersedia.

Kategori:

AngiospermsBiological ProductsComplex Mixtures +10

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HE3286 DB05212

small molecule | CAS: 1001100-69-1

Deskripsi belum tersedia.

Kategori:

17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12

Target Protein:

Nuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit

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Hedera helix leaf extract DB13194

biotech

Hedera helix leaf extract allergenic extract is used in allergenic testing.

Kategori:

Cough and Cold PreparationsExpectorants

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Helium He-3 DB12940

small molecule | CAS: 14762-55-1

Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI).

Kategori:

ElementsGasesNoble Gases

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Helminthosporium solani Approved DB10436

biotech

Helminthosporium solani is a fungus which can provoke allergic reactions. Helminthosporium solani extract is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

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Hematin DB13387

small molecule | CAS: 15489-90-4

Deskripsi belum tersedia.

Kategori:

Biological FactorsHemeHeterocyclic Compounds, Fused-Ring +3

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Heme arginate DB17310

biotech | CAS: 100438-92-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, BasicAmino Acids, Diamino +8

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Heme D DB03469

small molecule

Deskripsi belum tersedia.

Kategori:

Biological FactorsHeterocyclic Compounds, Fused-RingMetalloporphyrins +2

Target Protein:

Nitrite reductaseNitrite reductase

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Hemicellulase DB15820

biotech | CAS: 9025-56-3

Deskripsi belum tersedia.

Kategori:

EnzymesEnzymes and CoenzymesHydrolases

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Hemin Approved DB03404

biotech | CAS: 16009-13-5

Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

Kategori:

Biological FactorsBlood and Blood Forming OrgansHeme +5

Target Protein:

5-aminolevulinate synthase, non-specific, mitochondrial

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Hemoglobin crosfumaril DB13864

biotech | CAS: 142261-03-8

Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.

Kategori:

Amino Acids, Peptides, and ProteinsBenzene DerivativesBlood and Blood Forming Organs +10

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Hemoglobin glutamer-250 (bovine) DB19235

biotech | CAS: 192230-36-7

Hemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).

Kategori:

Amino Acids, Peptides, and ProteinsBiomimetic MaterialsBlood Proteins +5

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Hemoglobin raffimer DB13658

small molecule | CAS: 197462-97-8

Deskripsi belum tersedia.

Kategori:

Blood and Blood Forming OrgansBlood and Related ProductsBlood Substitutes and Perfusion Solutions +1

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Hemoporfin DB16183

small molecule | CAS: 14459-29-1

Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).

Kategori:

Biological FactorsDermatologicalsHeterocyclic Compounds, Fused-Ring +4

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Henagliflozin DB11939

small molecule | CAS: 1623804-44-3

Henagliflozin has been used in trials studying the treatment of Type 2 Diabetes.

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Henatinib DB13019

small molecule | CAS: 1239269-51-2

Henatinib has been used in trials studying the treatment of Advanced Solid Cancer.

Kategori:

Heterocyclic Compounds, Fused-RingVascular Endothelial Growth Factors, antagonists & inhibitors

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