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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (15718)

Halaman 131 / 315
Ethinamate Approved DB01031
small molecule | CAS: 126-52-3

Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally …

Kategori:
Acids, Acyclic
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh2.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethinylestradiol Approved DB00977
small molecule | CAS: 57-63-6

Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.[A191107] These properties were achieved by the substitution…

Kategori:
Adrenal Cortex HormonesAntineoplastic and Immunomodulating AgentsBSEP/ABCB11 inducers +48
Target Protein:
Estrogen receptorNuclear receptor subfamily 1 group I member 2
Waktu ParuhA 30µg oral dose ha…
Vol. DistribusiA 30µg oral dose ha…
KlirensEthinylestradiol ha…
Genetik -
Ethionamide Approved DB00609
small molecule | CAS: 536-33-4

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiinfectives for Systemic Use +9
Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]Nuclear factor erythroid 2-related factor 2Catalase-peroxidase
Waktu Paruh2 to 3 hours
Vol. Distribusi* 93.5 L [healthy v…
Klirens-
Genetik -
Ethoheptazine Approved DB08988
small molecule | CAS: 77-15-6

Ethoheptazine is marketed under the name Zactane. It is a phenazepine based opioid analgesic. It was invented in the 1950s and is related to other drugs such as proheptazine. Ethoheptazine is no longer marketed in the United States.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethosuximide Approved DB00593
small molecule | CAS: 77-67-8

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

Kategori:
Agents causing hyperkalemiaAnti-epileptic AgentAntiarrhythmic agents +18
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1G
Waktu Paruh53 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethotoin Approved DB00754
small molecule | CAS: 86-35-1

Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabili…

Kategori:
Anti-epileptic AgentAnticonvulsantsCardiovascular Agents +14
Target Protein:
Sodium channel protein type 5 subunit alphaNuclear receptor subfamily 1 group I member 2
Waktu Paruh3 to 9 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethoxyquin DB16866
small molecule | CAS: 91-53-2

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethoxzolamide DB00311
small molecule | CAS: 452-35-7

Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypoka…

Kategori:
AmidesBenzothiazolesCarbonic Anhydrase Inhibitors +9
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 4Carbonic anhydrase 7 +2
Waktu Paruh2.5-5.5 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lactase/phlorizin hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15400-53-0

Deskripsi belum tersedia.

Target Protein:
Dihydroneopterin aldolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Dual specificity protein kinase CLK1Dual specificity tyrosine-phosphorylation-regulated kinase 1ADual specificity protein kinase CLK3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducible
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducibleNitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 686723-15-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 548-00-5

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

Kategori:
4-HydroxycoumarinsAnticoagulantsBenzopyrans +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl butyrate DB15454
small molecule | CAS: 105-54-4

Ethyl butyrate is under investigation in clinical trial NCT03202342 (fMRI of Hypothalamic Responses to Taste, Temperature and Glucose).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl chloride Approved DB13259
small molecule | CAS: 75-00-3

Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the…

Kategori:
AnestheticsAnesthetics, LocalCentral Nervous System Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1623-14-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +7
Target Protein:
CholinesteraseParathion hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl ferulate Approved DB11285
small molecule | CAS: 4046-02-0

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicCinnamates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl hydroxybenzoate Approved DB13628
small molecule | CAS: 120-47-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAntifungals for Dermatological UseAntifungals for Topical Use +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29177-84-2

Deskripsi belum tersedia.

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepines and benzodiazepine derivatives +7
Target Protein:
GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl macadamiate Approved DB11243
small molecule

Ethyl macadamiate is derived from Macadamia terifolia seed oil. It is a non-volatile ester of ethyl alcohol and the fatty acids. Ethyl macadamiate is used in cosmetics and personal care products such as sunscreen, hair care products and skin care products as …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24393-56-4

Deskripsi belum tersedia.

Kategori:
Sunscreen Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 105-40-8

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCarbamates
Target Protein:
Shiga-like toxin 1 subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl nitrite DB16560
small molecule | CAS: 109-95-5

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIons +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 53074-96-7

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 41653-21-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl pyruvate DB05869
small molecule | CAS: 617-35-6

CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-rep…

Kategori:
Keto Acids
Target Protein:
Tumor necrosis factorHigh mobility group protein B1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl salicylate Approved DB15576
small molecule | CAS: 118-61-6

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Shiga-like toxin 1 subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3439-38-1

Deskripsi belum tersedia.

Target Protein:
Tetanus toxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 107-06-2

Deskripsi belum tersedia.

Kategori:
AlkanesEthaneHydrocarbons, Acyclic +2
Target Protein:
Haloalkane dehalogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylenediamine Approved DB14189
small molecule | CAS: 107-15-3

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer c…

Kategori:
AllergensAminesAntigens +6
Target Protein:
Dihydropteroate synthase
Waktu ParuhEthylenediamine has…
Vol. DistribusiVd = 0.133 l/kg [A3…
Klirens-
Genetik -
Ethylestrenol DB01493
small molecule | CAS: 965-90-2

An anabolic steroid with some progestational activity and little androgenic effect. [PubChem]

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +9
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylhexyl methoxycrylene Approved DB11226
small molecule | CAS: 947753-66-4

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states [F104]. It returns UV filters to their ground states without absorbing sunlight [F104]. It is used as a solve…

Waktu ParuhEthylhexyl methoxyc…
Vol. DistribusiEthylhexyl methoxyc…
KlirensEthylhexyl methoxyc…
Genetik -
small molecule | CAS: 70445-33-9

An emollient solvent with antimicrobial activity.

Kategori:
AlcoholsEthersSugar Alcohols +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 148-61-8

Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.

Target Protein:
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialSensor histidine kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 441-61-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylmorphine DB01466
small molecule | CAS: 76-58-4

A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a sched…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +22
Target Protein:
Mu-type opioid receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethynodiol diacetate Approved DB00823
small molecule | CAS: 297-76-7

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacet…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +19
Target Protein:
Progesterone receptorEstrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Eticlopride DB15492
small molecule | CAS: 84226-12-0

Deskripsi belum tersedia.

Kategori:
AmidesDopamine AgentsDopamine Antagonists +1
Target Protein:
D(2) dopamine receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etidocaine Approved DB08987
small molecule | CAS: 36637-18-0

Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

Kategori:
AcetanilidesAmidesAmines +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etidronic acid Approved DB01077
small molecule | CAS: 2809-21-4

Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.[A1923] Etidronate’s use has decr…

Kategori:
BisphosphonatesBone Density Conservation AgentsDrugs Affecting Bone Structure and Mineralization +4
Target Protein:
HydroxylapatiteReceptor-type tyrosine-protein phosphatase SV-type proton ATPase catalytic subunit A +3
Waktu ParuhThe half life of et…
Vol. DistribusiEtidronic acid has …
KlirensEtidronic acid has …
Genetik -
Etifoxine DB08986
small molecule | CAS: 21715-46-8

Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiaze…

Kategori:
Anti-Anxiety AgentsCentral Nervous System AgentsCentral Nervous System Depressants +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etigilimab DB18854
biotech | CAS: 2044984-83-8

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etilamfetamine DB13285
small molecule | CAS: 457-87-4

Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this amphetamine analog was used as an appetite suppressant in the 1…

Kategori:
Alimentary Tract and MetabolismAntiobesity Preparations, Excl. Diet ProductsCentrally Acting Antiobesity Products
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6501–6550 dari 15718
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