Hasil Filter

11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11778)

Halaman 126 / 236
Insulin aspart Approved DB01306
biotech | CAS: 116094-23-6

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhElimination half-li…
Vol. Distribusi-
Klirens1.2 L/h/kg
Genetik -
Insulin beef Approved DB09456
biotech | CAS: 11070-73-8

Insulin beef has been discontinued in the US and Canada since 2017.[L10827]

Kategori:
Alimentary Tract and MetabolismBlood Glucose Lowering AgentsCytochrome P-450 CYP1A2 Inducers +6
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Insulin degludec Approved DB09564
biotech | CAS: 844439-96-9

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the ac…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
InsulinInsulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhThe half-life after…
Vol. DistribusiUsing a one-compart…
KlirensThe mean apparent c…
Genetik -
Insulin detemir Approved DB01307
biotech | CAS: 169148-63-4

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenou…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhAfter subcutaneous …
Vol. DistribusiInsulin detemir has…
KlirensThe apparent cleara…
Genetik -
Insulin glargine Approved DB00047
biotech | CAS: 160337-95-1

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insuli…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsAntimetabolites +18
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Insulin glulisine Approved DB01309
biotech | CAS: 207748-29-6

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insu…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +15
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhElimination half li…
Vol. Distribusi13 L
Klirens-
Genetik -
Insulin human Approved DB00030
biotech | CAS: 11061-68-0

Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced ins…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptorCarboxypeptidase E +3
Waktu ParuhSystemic insulin di…
Vol. Distribusi-
Klirens-
Genetik -
Insulin icodec Approved DB16693
biotech | CAS: 1188379-43-2

Insulin icodec is an ultra long-acting basal insulin analogue. It is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life.[A264093] These modifications - which c…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +10
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhThe mean half-life …
Vol. DistribusiAccording to popula…
KlirensAccording to popula…
Genetik -
Insulin lispro Approved DB00046
biotech | CAS: 133107-64-9

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptid…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhAfter subcutaneous …
Vol. DistribusiWhen administered i…
KlirensWhen administered i…
Genetik -
biotech | CAS: 1200440-65-8

Deskripsi belum tersedia.

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +16
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Insulin pork Approved DB00071
biotech | CAS: 12584-58-6

Insulin isolated from pig pancreas. Composed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 874442-57-6

Deskripsi belum tersedia.

Kategori:
Blood Glucose Lowering AgentsCytochrome P-450 CYP1A2 InducersCytochrome P-450 CYP1A2 Inducers (strength unknown) +3
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 67763-97-7

The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biol…

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Proteins +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
INT41 DB17935
biotech

INT41 (also known as rAAV6-INT41) is a recombinant adeno-associated virus vector containing DNA encoding INT41 intrabody.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intepirdine DB12680
small molecule | CAS: 607742-69-8

Intepirdine has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
Heterocyclic Compounds, Fused-RingSulfur Compounds
Target Protein:
5-hydroxytryptamine receptor 6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfa DB05258
biotech

Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-? subtypes and is purified by affinity chromatography. Interferon alp…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntiviral Agents +14
Target Protein:
Interferon alpha/beta receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfa-2a Approved DB00034
biotech | CAS: 76543-88-9

Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used ext…

Kategori:
Adjuvants, ImmunologicAlfa InterferonsAmino Acids, Peptides, and Proteins +20
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu ParuhThe IM half-life of…
Vol. Distribusi* 0.223 to 0.748 L/…
Klirens* 2.14 - 3.62 mL/mi…
Genetik -
biotech | CAS: 142192-09-4

Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytochrome P-450 CYP1A2 Inhibitors +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfa-n1 Approved DB00011
biotech | CAS: 74899-72-2

Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alp…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +13
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh1.2 hours (mammalia…
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfa-n3 Approved DB00018
biotech

Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).

Kategori:
Alfa InterferonsAmino Acids, Peptides, and ProteinsBiological Factors +13
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon beta-1b Approved DB00068
biotech | CAS: 145155-23-3

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +15
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh-
Vol. Distribusi* 0.25 to 2,88 L/kg
Klirens* 9.4 – 28.9 mL/min…
Genetik -
biotech

Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. It has antitumor properties, antiviral activities, and important immunoregulatory functions. The interferon is primarily produced by activated T lymphocytes and natural killer…

Kategori:
Adjuvants, ImmunologicAntineoplastic and Immunomodulating AgentsInterferons
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide conserved in type I inter…

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon tau DB16972
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntiviral Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interleukin-7 DB11997
biotech | CAS: 858376-81-5

Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intermedine DB17612
biotech | CAS: 581-05-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAmino Acids, Peptides, and ProteinsHeterocyclic Compounds, Fused-Ring +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intetumumab DB12701
biotech | CAS: 725735-28-4

Intetumumab has been used in trials studying the treatment of Melanoma.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intoplicine DB12868
small molecule | CAS: 125974-72-3

Intoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inupadenant DB19129
small molecule | CAS: 2246607-08-7

Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).

Target Protein:
Adenosine receptor A2a
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
INVAC-1 DB16196
biotech | CAS: 1708137-44-3

INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Invert sugar DB09344
small molecule | CAS: 8013-17-0

Invert sugar is obtained from sugar cane when this is treated with dilute acid or with the invertase enzyme. It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case o…

Kategori:
Antivaricose TherapyCarbohydratesCariogenic Agents +14
Waktu ParuhThe glucose half-li…
Vol. Distribusi-
Klirens-
Genetik -
INZ-701 DB17629
biotech

INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IO-202 DB17548
biotech

IO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iobenguane Approved DB06704
small molecule | CAS: 80663-95-2

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionu…

Kategori:
AmidinesBenzene DerivativesCompounds used in a research, industrial, or household setting +16
Target Protein:
Sodium-dependent noradrenaline transporter
Waktu ParuhPhysical half life …
Vol. Distribusi-
Klirens-
Genetik -
Iobenzamic acid DB13428
small molecule | CAS: 3115-05-7

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iobitridol Approved DB12407
small molecule | CAS: 136949-58-1

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iocarmic acid DB13755
small molecule | CAS: 10397-75-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iocetamic acid Approved DB09403
small molecule | CAS: 16034-77-8

Iocetamic acid is a diagnostic aid (radiopaque medium)

Kategori:
Benzene DerivativesContrast MediaHydrocarbons, Halogenated +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodide Approved DB12754
small molecule | CAS: 20461-54-5

Iodide has been investigated for the treatment of Goiter, Nodular.

Kategori:
AnionsElectrolytesIodides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodine Approved DB05382
small molecule | CAS: 7553-56-2

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A1921…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +12
Target Protein:
Sodium/iodide cotransporterMicrobial proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 56897-09-7

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesDiagnostic Radiopharmaceuticals +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2420475-06-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodine I-125 DB14804
small molecule | CAS: 14158-31-7

Iodine I-125 is under investigation in clinical trial NCT00079417 (Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1000874-23-6

Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodine povacrylex Approved DB09537
small molecule | CAS: 845736-10-9

Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity. DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the prepara…

Kategori:
Anti-Infective Agents, Local
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
Iodipamide Approved DB04711
small molecule | CAS: 606-17-7

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Target Protein:
Albumin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 42220-21-3

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsIodine (131I) Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 123748-56-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6251–6300 dari 11778
Sebelumnya Halaman 126 / 236 Berikutnya