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11793

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11793 (100.0%)

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Halaman 126 / 236
Iobenguane sulfate I-123 Approved DB09546
small molecule | CAS: 80663-95-2

Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].

Kategori:
Drugs that are Mainly Renally ExcretedRadioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Iobitridol Approved DB12407
small molecule | CAS: 136949-58-1

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Iocetamic acid Approved DB09403
small molecule | CAS: 16034-77-8

Iocetamic acid is a diagnostic aid (radiopaque medium)

Kategori:
Benzene DerivativesContrast MediaHydrocarbons, Halogenated +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodide Approved DB12754
small molecule | CAS: 20461-54-5

Iodide has been investigated for the treatment of Goiter, Nodular.

Kategori:
AnionsElectrolytesIodides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh-
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Iodide I-123 Approved DB09420
small molecule | CAS: 69239-56-1

Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid g…

Kategori:
Diagnostic RadiopharmaceuticalsElementsHalogens +6
Waktu ParuhIodine-123 decays b…
Vol. Distribusi-
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Iodine Approved DB05382
small molecule | CAS: 7553-56-2

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A1921…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +12
Target Protein:
Sodium/iodide cotransporterMicrobial proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 56897-09-7

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesDiagnostic Radiopharmaceuticals +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2420475-06-3

Deskripsi belum tersedia.

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biotech | CAS: 1000874-23-6

Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

Waktu Paruh-
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Iodine povacrylex Approved DB09537
small molecule | CAS: 845736-10-9

Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity. DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the prepara…

Kategori:
Anti-Infective Agents, Local
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
Iodipamide Approved DB04711
small molecule | CAS: 606-17-7

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Target Protein:
Albumin
Waktu Paruh-
Vol. Distribusi-
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Iodixanol Approved DB01249
small molecule | CAS: 92339-11-2

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu Paruh2.1 hours. In patie…
Vol. Distribusi* 0.26 L/kg
Klirens-
Genetik -
small molecule | CAS: 123748-56-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated +2
Waktu Paruh-
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Iodoform Approved DB13813
small molecule | CAS: 75-47-8

Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions [A32890]. Due to its antimicrobial properties following topi…

Kategori:
DermatologicalsHydrocarbons, HalogenatedMedicated Dressings +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Iodohippurate sodium I-123 Approved DB09448
small molecule | CAS: 56254-07-0

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsRenal System
Waktu Paruh-
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Genetik -
small molecule | CAS: 55406-53-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAllergensAntigens +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ioflupane F-18 DB16913
small molecule | CAS: 186381-69-1

Deskripsi belum tersedia.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
Waktu Paruh-
Vol. Distribusi-
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Ioglicic acid DB13701
small molecule | CAS: 49755-67-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +5
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Ioglycamic acid DB13741
small molecule | CAS: 2618-25-9

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iohexol Approved DB01362
small molecule | CAS: 66108-95-0

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmo…

Kategori:
Acids, CarbocyclicAgents that reduce seizure thresholdBenzene Derivatives +12
Waktu ParuhIntrathecal half-li…
Vol. Distribusi* 350-849 mL/kg
Klirens* 109 mL/min [Adult…
Genetik -
Iomeprol Approved DB11705
small molecule | CAS: 78649-41-9

Iomeprol has been investigated for the diagnostic of Coronary Artery Disease.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
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ION283 DB18162
biotech

Deskripsi belum tersedia.

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ION356 DB19389
biotech

Deskripsi belum tersedia.

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IONIS-FGFR4Rx DB16198
biotech | CAS: 1416376-17-4

IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients).

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IONIS-HBVRx DB16202
biotech | CAS: 1403787-62-1

IONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).

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Iopamidol Approved DB08947
small molecule | CAS: 60166-93-0

Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu Paruh-
Vol. Distribusi-
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Iopanoic acid Approved DB08946
small molecule | CAS: 96-83-3

Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Waktu Paruh-
Vol. Distribusi-
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Iopentol DB13861
small molecule | CAS: 89797-00-2

Iopentol is used as a contrast medium.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Iophendylate Approved DB01187
small molecule | CAS: 99-79-6

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Waktu Paruh-
Vol. Distribusi-
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Iopodic acid Approved DB09333
small molecule | CAS: 5587-89-3

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6.[A32080] Due to its particular structure, it presents a hi…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Target Protein:
Thyroxine 5-deiodinase
Waktu Paruh-
Vol. Distribusi-
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small molecule | CAS: 873438-88-1

Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).

Kategori:
AlcoholsBenzene DerivativesEthers +12
Waktu Paruh-
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Iopromide Approved DB09156
small molecule | CAS: 73334-07-3

Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures …

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +8
Waktu ParuhAfter intravenous a…
Vol. DistribusiThe total volume of…
KlirensThe mean total and …
Genetik -
small molecule | CAS: 9062-07-1

iota-Carrageenan is under investigation in clinical trial NCT01944631 (Iota-Carrageenan Nasal Spray in Common Cold).

Kategori:
CarbohydratesPolysaccharides
Waktu Paruh-
Vol. Distribusi-
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Iothalamic acid Approved DB09133
small molecule | CAS: 2276-90-6

Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +16
Waktu ParuhIn patients with no…
Vol. Distribusi-
Klirens-
Genetik -
Ioversol Approved DB09134
small molecule | CAS: 87771-40-2

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.[L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays.[L4…

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu ParuhThe elimination hal…
Vol. DistribusiIn adults, the volu…
KlirensIn healthy voluntee…
Genetik -
Ioxaglic acid Approved DB09313
small molecule | CAS: 59017-64-0

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance …

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Waktu ParuhHexabrix 320 is rap…
Vol. DistribusiIoxaglate salts cro…
Klirens245 ml/kg [L1886]
Genetik -
Ioxilan Approved DB09135
small molecule | CAS: 107793-72-6

Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant …

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu ParuhAn initial fast dis…
Vol. DistribusiIoxilan is distribu…
KlirensThe total clearance…
Genetik -
Ioxitalamic acid Approved DB13444
small molecule | CAS: 28179-44-4

Ioxitalamate is an ionic iodinated contrast medium.[A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.[A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Lie…

Kategori:
Acids, CarbocyclicAlcoholsAmino Sugars +12
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe total clearance…
Genetik -
IP-2018 DB19049
small molecule | CAS: 881387-68-4

IP-2018 is under investigation in clinical trial NCT04686916 (Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients).

Waktu Paruh-
Vol. Distribusi-
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IP501 DB06450
small molecule

IP-501 is an investigational antifibrotic compound being tested for the treatment of alcohol-induced liver disease and chronic hepatitis-C-induced cirrhosis. The compound was developed by Indevus Pharmaceuticals.

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Vol. Distribusi-
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Ipafricept DB15045
biotech | CAS: 1391727-24-4

Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsGlobulins +10
Waktu Paruh-
Vol. Distribusi-
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Ipatasertib DB11743
small molecule | CAS: 1001264-89-6

Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.

Kategori:
Antineoplastic AgentsEnzyme InhibitorsProtein Kinase Inhibitors +1
Target Protein:
RAC-alpha serine/threonine-protein kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Ipecac Approved DB13293
small molecule | CAS: 8012-96-2

Ipecac is obtained from the plant _Cephaelis ipecacuanha_ and contains a number of emetic alkaloids including emetine and cephaeline.[L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued.[L1113] The FDA does not ha…

Kategori:
Agents Causing Muscle ToxicityAntidotesAutonomic Agents +15
Waktu ParuhThe effect of ipeca…
Vol. DistribusiThe volume of distr…
KlirensThe urinary excreti…
Genetik -
IPH 2101 DB06049
biotech | CAS: 1000676-42-5

IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IPI-493 DB13023
small molecule | CAS: 64202-81-9

IPI-493 has been used in trials studying the treatment of Advanced Malignancies.

Kategori:
AmidesHSP90 Heat-Shock Proteins, antagonists & inhibitorsLactams +2
Target Protein:
Heat shock protein HSP 90-alpha
Waktu Paruh-
Vol. Distribusi-
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Genetik -
IPI-549 DB16296
small molecule | CAS: 1693758-51-8

IPI-549 is under investigation in clinical trial NCT03795610 (Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma).

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ipidacrine DB13668
small molecule | CAS: 62732-44-9

Deskripsi belum tersedia.

Kategori:
Anti-Dementia DrugsCholinesterase InhibitorsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
Vol. Distribusi-
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Ipilimumab Approved DB06186
biotech | CAS: 477202-00-9

Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).[L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntibodies +21
Target Protein:
Cytotoxic T-lymphocyte protein 4
Waktu ParuhIpilimumab has a ha…
Vol. DistribusiThe volume of distr…
KlirensIpilimumab has a cl…
Genetik -
IPL-344 DB16958
small molecule | CAS: 877120-59-7

Deskripsi belum tersedia.

Waktu Paruh-
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Ipragliflozin DB11698
small molecule | CAS: 761423-87-4

Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

Kategori:
Alimentary Tract and MetabolismBlood Glucose Lowering AgentsCarbohydrates +6
Target Protein:
Sodium/glucose cotransporter 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6251–6300 dari 11793
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