Hasil Filter

12560

Total database: 17430
Struktur (SMILES)
9109 (72.5%)
Target
6912 (55.0%)
Genomik
109 (0.9%)
Referensi
12560 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (12560)

Halaman 124 / 252
GW810781 DB16032
small molecule | CAS: 280571-30-4

GW810781 is under investigation in clinical trial NCT00046332 (A Study Comparing 4 Doses of GW810781 Versus Placebo in Hiv-infected Patients).

Kategori:
Anti-HIV Agents
Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GW842166 DB11903
small molecule | CAS: 666260-75-9

GW842166X has been used in trials studying the treatment of Pain, Analgesia, Inflammation, Osteoarthritis, and Pain, Inflammatory, among others.

Kategori:
Agents producing tachycardiaCannabinoid Receptor AgonistsCannabinoids and similars +1
Target Protein:
Cannabinoid receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GX-19 Vaccine DB15891
biotech

The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GYM329 DB18590
biotech

GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GZ-389988 DB16056
small molecule | CAS: 1788906-96-6

GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee).

Target Protein:
NT-3 growth factor receptorHigh affinity nerve growth factor receptorBDNF/NT-3 growth factors receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
H-89 DB07995
small molecule | CAS: 127243-85-0

Deskripsi belum tersedia.

Kategori:
AmidesEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +3
Target Protein:
cAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase inhibitor alphaSerine/threonine-protein kinase haspin +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
H3B-6527 DB15169
small molecule | CAS: 1702259-66-2

H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Fibroblast growth factor receptor 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
H3B-8800 DB14017
small molecule | CAS: 1825302-42-8

H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551]. It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferent…

Target Protein:
Splicing factor 3B subunit 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haddock Approved DB10615
biotech

Haddock allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haemagglutinin-strain B Approved DB15482
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vacci…

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hafnium oxide DB17508
small molecule | CAS: 12055-23-1

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesElements +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Halcinonide Approved DB06786
small molecule | CAS: 3093-35-4

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Labora…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +13
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haletazole DB15942
small molecule | CAS: 15599-36-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Halicin DB15624
small molecule | CAS: 40045-50-9

Deskripsi belum tersedia.

Kategori:
Sulfur CompoundsThiazoles
Target Protein:
c-Jun N-terminal kinases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Halofantrine Approved DB01218
small molecule | CAS: 69756-53-2

Halofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poiso…

Kategori:
Agents that reduce seizure thresholdAnti-Infective AgentsAntimalarials +13
Target Protein:
Fe(II)-protoporphyrin IXCalmodulin-1Calmodulin-3 +3
Waktu Paruh6-10 days
Vol. Distribusi-
Klirens-
Genetik -
Halofuginone DB04866
small molecule | CAS: 55837-20-2

Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Bio…

Kategori:
Angiogenesis InhibitorsAngiogenesis Modulating AgentsAnti-Infective Agents +10
Target Protein:
Collagen alpha-1(I) chain72 kDa type IV collagenase
Waktu Paruh23.8 to 72.1 hours
Vol. Distribusi-
Klirens-
Genetik -
Halometasone DB13728
small molecule | CAS: 50629-82-8

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroids +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloperidol Approved DB00502
small molecule | CAS: 52-86-8

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.[A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A274…

Kategori:
Agents that reduce seizure thresholdAnti-Dyskinesia AgentsAntidepressive Agents +50
Target Protein:
5-hydroxytryptamine receptor 2CD(2) dopamine receptor5-hydroxytryptamine receptor 2A +15
Waktu ParuhFollowing oral admi…
Vol. DistribusiThe apparent volume…
KlirensFollowing intraveno…
Genetik -
Halothane Approved DB01159
small molecule | CAS: 151-67-7

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxatio…

Kategori:
Agents that produce hypertensionAnestheticsAnesthetics, General +14
Target Protein:
Potassium channel subfamily K member 3Potassium channel subfamily K member 9GABA(A) Receptor +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxazolam DB01476
small molecule | CAS: 59128-97-1

Deskripsi belum tersedia.

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxon DB11419
small molecule | CAS: 321-55-1

Deskripsi belum tersedia.

Kategori:
BenzopyransCoumarinsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxyfop-P DB07870
small molecule | CAS: 95977-29-0

Deskripsi belum tersedia.

Target Protein:
Acetyl-CoA carboxylase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hard fat Approved DB11578
small molecule

Deskripsi belum tersedia.

Kategori:
Pharmaceutical Vehicles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Harmaline DB13875
small molecule | CAS: 304-21-2

Deskripsi belum tersedia.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAlkaloids +14
Target Protein:
Histamine N-methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Harmine DB07919
small molecule | CAS: 442-51-3

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntidepressive AgentsCarbolines +13
Target Protein:
Dual specificity tyrosine-phosphorylation-regulated kinase 2Dual specificity tyrosine-phosphorylation-regulated kinase 3Dual specificity tyrosine-phosphorylation-regulated kinase 1A +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hazelnut Approved DB10654
biotech

Hazelnut allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HCV-086 DB05884
small molecule

HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.

Target Protein:
Genome polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HE-2200 DB06257
small molecule | CAS: 2697-85-0

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesFused-Ring Compounds +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HE3286 DB05212
small molecule | CAS: 1001100-69-1

Deskripsi belum tersedia.

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12
Target Protein:
Nuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Helium Approved DB09155
small molecule | CAS: 7440-59-7

Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table. Its boiling and melting …

Kategori:
ElementsGasesMedical Gases +3
Waktu Paruh0.8 seconds
Vol. Distribusi-
Klirens-
Genetik -
Helium He-3 DB12940
small molecule | CAS: 14762-55-1

Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI).

Kategori:
ElementsGasesNoble Gases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hematin DB13387
small molecule | CAS: 15489-90-4

Deskripsi belum tersedia.

Kategori:
Biological FactorsHemeHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hematoxylin DB16871
small molecule | CAS: 517-28-2

Deskripsi belum tersedia.

Kategori:
BenzopyransColoring AgentsCompounds used in a research, industrial, or household setting +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemicellulase DB15820
biotech | CAS: 9025-56-3

Deskripsi belum tersedia.

Kategori:
EnzymesEnzymes and CoenzymesHydrolases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemin Approved DB03404
biotech | CAS: 16009-13-5

Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

Kategori:
Biological FactorsBlood and Blood Forming OrgansHeme +5
Target Protein:
5-aminolevulinate synthase, non-specific, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoglobin Approved DB04945
biotech | CAS: 9008-02-0

The respiratory protein of the red blood cells. It consists primarily of globin and heme.

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsGlobins +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 192230-36-7

Hemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).

Kategori:
Amino Acids, Peptides, and ProteinsBiomimetic MaterialsBlood Proteins +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 679404-95-6

Hemoglobin glutamer-256 (human) is under investigation in clinical trial NCT00076648 (Safety and Efficacy of Polyheme(r) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-hospital Setting).

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsBlood Substitutes +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 197462-97-8

Deskripsi belum tersedia.

Kategori:
Blood and Blood Forming OrgansBlood and Related ProductsBlood Substitutes and Perfusion Solutions +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoporfin DB16183
small molecule | CAS: 14459-29-1

Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).

Kategori:
Biological FactorsDermatologicalsHeterocyclic Compounds, Fused-Ring +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hemoximer DB17600
biotech

Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.[A258528]

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsBlood Proteins +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Henatinib DB13019
small molecule | CAS: 1239269-51-2

Henatinib has been used in trials studying the treatment of Advanced Solid Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingVascular Endothelial Growth Factors, antagonists & inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heparin Approved DB01109
small molecule | CAS: 9005-49-6

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III …

Kategori:
Agents causing hyperkalemiaAnticoagulantsAntivaricose Therapy +16
Target Protein:
Antithrombin-IIICoagulation factor XP-selectin +9
Waktu ParuhThe plasma half-lif…
Vol. DistribusiThe volume of distr…
KlirensThe clearance in ad…
Genetik -
Menampilkan 6151–6200 dari 12560
Sebelumnya Halaman 124 / 252 Berikutnya