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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 123 / 349
Cyclothiazide Approved DB00606
small molecule | CAS: 2259-96-3

As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport…

Kategori:
Antihypertensive AgentsCardiovascular AgentsDiuretics +11
Target Protein:
Sodium/potassium-transporting ATPase subunit gammaCarbonic anhydraseCarbonic anhydrase 2 +2
Waktu Paruh-
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Cyclouridine DB04627
small molecule | CAS: 3736-77-4

Deskripsi belum tersedia.

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleosidesPyrimidine Nucleosides +2
Target Protein:
Uridine phosphorylase
Waktu Paruh-
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Cycrimine Approved DB00942
small molecule | CAS: 77-39-4

Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.

Kategori:
Agents producing tachycardiaAnticholinergic AgentsMuscarinic Antagonists
Target Protein:
Muscarinic acetylcholine receptor M1
Waktu Paruh-
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biotech

Deskripsi belum tersedia.

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biotech

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biotech

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biotech

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Cyfluthrin DB13828
small molecule | CAS: 68359-37-5

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAntiparasitic Products, Insecticides and RepellentsCompounds used in a research, industrial, or household setting +9
Waktu Paruh-
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Cymarin DB13240
small molecule | CAS: 508-77-0

Deskripsi belum tersedia.

Kategori:
Antiarrhythmic agentsCarbohydratesCardanolides +12
Waktu Paruh-
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CYNK-001 DB15722
biotech

CYNK-001 is a novel allogenic off-the-shelf natural killer (NK) cell therapy originating from human placental CD34+ hematopoietic stem cells and enriched with CD56+/CD3-.

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CYNK-101 DB18637
biotech

CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).

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Cynodon dactylon pollen Approved DB10351
biotech

Cynodon dactylon pollen, also known as bermuda grass pollen, is a standardized grass pollen extracts used for the diagnosis and treatment of allergic disease to grass pollen. It can be cutaneously, intradermally and subcutaneously administered to initiate an …

Kategori:
Allergenic ExtractsCell-mediated ImmunityGrass Pollen Allergen Extracts +3
Waktu Paruh-
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CYP-001 DB15739
biotech

CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm. When activated with fibroblast growth factor-2 (FGF-2), MCAs create colonies with specific phenotypes. These cells are then able to differen…

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CypCaps DB17435
biotech

Deskripsi belum tersedia.

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Cypermethrin DB13721
small molecule | CAS: 52315-07-8

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAntiparasitic Products, Insecticides and RepellentsCompounds used in a research, industrial, or household setting +9
Waktu Paruh-
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Cyprenorphine DB01480
small molecule | CAS: 4406-22-8

Deskripsi belum tersedia.

Kategori:
AlkaloidsHeterocyclic Compounds, Fused-RingOpiate Alkaloids +1
Waktu Paruh-
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Cyproheptadine Approved DB00434
small molecule | CAS: 129-03-3

Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.[L32474] It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and its off-label use in the tr…

Kategori:
Agents producing tachycardiaAgents that reduce seizure thresholdAnti-Allergic Agents +28
Target Protein:
Histamine H1 receptor5-hydroxytryptamine receptor 2A5-hydroxytryptamine receptor 2C +6
Waktu Paruh-
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Cyproterone acetate Approved DB04839
small molecule | CAS: 427-51-0

An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of …

Kategori:
Adrenal Cortex HormonesAntiandrogensAntiandrogens and Estrogens +27
Target Protein:
Androgen receptorProstate-specific antigen
Waktu ParuhElimination Followi…
Vol. Distribusi-
Klirens-
Genetik -
Cysteamine Approved DB00847
small molecule | CAS: 60-23-1

Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, es…

Kategori:
Alimentary Tract and MetabolismAminesAmino Acids and Derivatives +11
Target Protein:
SomatostatinCystineNeuropeptide Y receptor type 2
Waktu ParuhThe half-life of cy…
Vol. DistribusiCysteamine has a vo…
KlirensThe plasma clearanc…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyproteinProteinase inhibitor I4, serpin
Waktu Paruh-
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Cysteinamide DB03275
small molecule | CAS: 74401-72-2

Deskripsi belum tersedia.

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Cysteine Approved DB00151
small molecule | CAS: 52-90-4

A thiol-containing non-essential amino acid that is oxidized to form cystine.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +9
Target Protein:
Glutamate--cysteine ligase regulatory subunitGlutamate--cysteine ligase catalytic subunitAspartate aminotransferase, cytoplasmic +10
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 17528-66-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3
Target Protein:
Ribonuclease pancreatic2'-5'-oligoadenylate synthase 1
Waktu Paruh-
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Genetik -
biotech

Cystic fibrosis transmembrane conductance regulator is under investigation in clinical trial NCT00004806 (Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis).

Kategori:
Amino Acids, Peptides, and ProteinsAnion Transport ProteinsATP-Binding Cassette Transporters +12
Waktu Paruh-
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Cystine Approved DB00138
small molecule | CAS: 56-89-3

A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.

Kategori:
Amino AcidsAmino Acids, DiaminoAmino Acids, Dicarboxylic +12
Target Protein:
Cystine/glutamate transporterCystinosin
Waktu Paruh-
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CYT-6091 DB05991
small molecule

CYT-6091 (Aurimune) is an investigational small molecule made up of recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol bound to the surface of 27 nm colloidal gold particles. It was under investagtion in clinical trials N…

Kategori:
AlcoholsCompounds used in a research, industrial, or household settingElements +7
Waktu Paruh-
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CYT006-AngQb DB05739
biotech

CYT006-AngQb is a therapeutic vaccine in development for treatment of hypertension. It is designed to instruct the patient’s immune system to produce an antibody response against angiotensin II, a small peptide that causes blood vessels to narrow and results…

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Type-1 angiotensin II receptorType-2 angiotensin II receptor
Waktu Paruh4 months
Vol. Distribusi-
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CYT007-TNFQb DB05758
biotech

CYT007-TNFQb is an active immunization therapy that aims at providing a novel treatment to people suffering from RA or psoriasis. The vaccine should allow for administration of low amounts of drug to individual patients (in the microgram range) and for conv…

Target Protein:
Tumor necrosis factor
Waktu Paruh-
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CYT997 DB05147
small molecule

CYT997 is an orally available vascular targeting and cytotoxic agent that has proven effective in animal models of a wide range of tumour types including breast, prostate and colon, as well as some leukemias.

Target Protein:
Tubulin alpha-1A chainTubulin alpha-1B chainTubulin alpha-1C chain +12
Waktu Paruh-
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Cytarabine Approved DB00987
small molecule | CAS: 147-94-4

A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of …

Kategori:
Agents Causing Muscle ToxicityAnti-Infective AgentsAntimetabolites +23
Target Protein:
DNA polymerase betaDNA polymerase catalytic subunitDNA
Waktu Paruh10 minutes
Vol. Distribusi-
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Cythioate DB11392
small molecule | CAS: 115-93-5

Cythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.

Kategori:
AgrochemicalsCompounds used in a research, industrial, or household settingInsecticides +4
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Cytidine DB02097
small molecule | CAS: 65-46-3

Deskripsi belum tersedia.

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleosidesPyrimidine Nucleosides +2
Target Protein:
Uridine-cytidine kinase 2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 84-52-6

Deskripsi belum tersedia.

Kategori:
Cytosine NucleotidesNucleic Acids, Nucleotides, and NucleosidesNucleotides +3
Target Protein:
Ribonuclease pancreatic
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycerol-3-phosphate cytidylyltransferase
Waktu Paruh-
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Genetik -
small molecule | CAS: 63-38-7

Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate. [PubChem]

Target Protein:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase3-deoxy-manno-octulosonate cytidylyltransferase2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase +3
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
CDP-glucose 4,6-dehydratase
Waktu Paruh-
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Genetik -
small molecule | CAS: 63-37-6

A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.

Kategori:
Cytosine NucleotidesNucleic Acids, Nucleotides, and NucleosidesNucleotides +3
Target Protein:
Uridine-cytidine kinase 23-deoxy-manno-octulosonate cytidylyltransferase2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein. [PubChem]

Target Protein:
N-acylneuraminate cytidylyltransferase
Waktu Paruh-
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Genetik -
small molecule | CAS: 65-47-4

Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]

Target Protein:
P2Y purinoceptor 43-deoxy-manno-octulosonate cytidylyltransferaseUridine-cytidine kinase 2 +6
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

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Cytisine DB09028
small molecule | CAS: 485-35-8

Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement…

Kategori:
AlkaloidsDrugs Used in Addictive DisordersDrugs Used in Nicotine Dependence +5
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Neuronal acetylcholine receptor subunit beta-4Neuronal acetylcholine receptor subunit alpha-4 +4
Waktu Paruh4.8 hours.
Vol. DistribusiOral: 6.2 l/kg Oral…
KlirensRenal: 43 mL/min.
Genetik -
biotech

Cytisus scoparius flowering top allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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Cytochalasin B DB16766
small molecule | CAS: 14930-96-2

Deskripsi belum tersedia.

Kategori:
Biological FactorsCytochalasinsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
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Cytochlor DB12383
small molecule | CAS: 32387-56-7

Cytochlor has been used in trials studying the treatment of Head and Neck Cancer and Brain and Central Nervous System Tumors.

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Cytochrome C DB18543
biotech | CAS: 9007-43-6

Cytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain.

Kategori:
Amino Acids, Peptides, and ProteinsCytochrome c GroupCytochromes +3
Waktu Paruh-
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CZEN 002 DB05479
small molecule

CZEN-002 is a novel, non-azole anti-fungal synthetic octapeptide, derived from alpha-Melanocyte-Stimulating Hormone (a-MSH). CZEN-002 modulates inflammatory and immune responses. It has also been shown to kill Candida albicans (C. albicans), a single-celled f…

Target Protein:
Melanocyte-stimulating hormone receptor
Waktu Paruh-
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small molecule

A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]

Target Protein:
6,7-dimethyl-8-ribityllumazine synthase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chymotrypsinogen B
Waktu Paruh-
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Genetik -
Menampilkan 6101–6150 dari 17430
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