Hasil Filter

11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11778)

Halaman 122 / 236
Indatraline DB17032
small molecule | CAS: 86939-10-8

Indatraline is a nonselective monoamine reuptake inhibitor.[A253022]

Kategori:
AminesIndenes
Target Protein:
Sodium-dependent dopamine transporter
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1238517-16-2

Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAntibodies +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indecainide Approved DB00192
small molecule | CAS: 74517-78-5

Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.

Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indeglitazar DB07724
small molecule | CAS: 835619-41-5

Deskripsi belum tersedia.

Target Protein:
Peroxisome proliferator-activated receptor alphaPeroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor delta +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indenolol DB08952
small molecule | CAS: 60607-68-3

Indenolol is a drug of the beta-adrenergic blocker class.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indian frankincense Approved DB14275
biotech

Indian frankincense is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indigotindisulfonic acid Approved DB11577
small molecule | CAS: 483-20-5

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in …

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingDiagnostic Agents +5
Target Protein:
Alpha adrenergic receptor
Waktu ParuhIn healthy adults g…
Vol. DistribusiThe volume of distr…
KlirensIn healthy adults g…
Genetik -
Indinavir Approved DB00224
small molecule | CAS: 150378-17-9

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +33
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh1.8 (± 0.4) …
Vol. Distribusi-
Klirens-
Genetik -
Indiplon DB12590
small molecule | CAS: 325715-02-4

Indiplon has been used in trials studying the treatment of Insomnia and Depression.

Kategori:
BenzazepinesCentral Nervous System AgentsCentral Nervous System Depressants +7
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indirubin DB12379
small molecule | CAS: 479-41-4

Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).

Kategori:
Antibiotics, AntineoplasticAntineoplastic AgentsColoring Agents +4
Target Protein:
Cytochrome P450 1A1Aryl hydrocarbon receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 244021-67-8

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle formCell division control protein 2 homolog
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indisulam DB06370
small molecule | CAS: 165668-41-7

Deskripsi belum tersedia.

Kategori:
AmidesAntineoplastic AgentsCarbonic Anhydrase Inhibitors +15
Target Protein:
Carbonic anhydrase 9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium DB11659
small molecule | CAS: 7440-74-6

Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma.

Kategori:
AnionsElectrolytesElements +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 131391-70-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 DB11916
small molecule | CAS: 15750-15-9

Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 156586-92-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 oxyquinoline Approved DB09473
small molecule | CAS: 65389-08-4

Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron ca…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu ParuhIndium In 111 decay…
Vol. Distribusi-
KlirensClearance from whol…
Genetik -
biotech | CAS: 138955-27-8

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.

Kategori:
AcetatesAcids, AcyclicAmines +14
Target Protein:
Tumor-associated glycoprotein 72 (TAG-72)
Waktu Paruh0.8 hours (mammalia…
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 139096-04-1

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic Agent
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indocyanine green acid form Approved DB09374
small molecule | CAS: 28782-33-4

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl…

Kategori:
BSEP/ABCB11 SubstratesCardiac FunctionColoring Agents +6
Waktu ParuhICG has a half-life…
Vol. DistribusiICG distribution in…
KlirensClearance of dyes w…
Genetik -
Indole DB04532
small molecule | CAS: 120-72-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
EndolysinNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 700-06-1

Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsCompounds used in a research, industrial, or household setting +2
Target Protein:
NF-kappa-B inhibitor alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Tryptophan synthase alpha chainTryptophan synthase beta chainTryptophan synthase alpha chain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indoleacetamide DB08652
small molecule | CAS: 879-37-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Target Protein:
Aralkylamine dehydrogenase light chainAralkylamine dehydrogenase heavy chain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 87-51-4

Deskripsi belum tersedia.

Kategori:
Growth SubstancesHeterocyclic Compounds, Fused-RingIndoles +1
Target Protein:
Group IIE secretory phospholipase A2S-phase kinase-associated protein 1Kynurenine--oxoglutarate transaminase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 830-96-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +2
Target Protein:
Group IIE secretory phospholipase A2Aspartate aminotransferaseAromatic-amino-acid aminotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indomethacin Approved DB00328
small molecule | CAS: 53-86-1

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an ind…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +49
Target Protein:
Prostaglandin G/H synthase 2Phospholipase A2, membrane associatedHuman Cyclooxygenases +8
Waktu ParuhIndometacin disposi…
Vol. DistribusiThe volume of distr…
KlirensIn a clinical pharm…
Genetik -
Indotecan DB18752
small molecule | CAS: 915303-09-2

Deskripsi belum tersedia.

Kategori:
DioxolesDNA Topoisomerases, Type IHeterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indoximod DB12827
small molecule | CAS: 110117-83-4

Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +2
Target Protein:
Indoleamine 2,3-dioxygenase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indoxyl sulfate DB07992
small molecule | CAS: 487-94-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indralin DB18220
small molecule | CAS: 156691-86-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesReceptors, Retinoic Acid, agonistsSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inebilizumab Approved DB12530
biotech | CAS: 1299440-37-1

Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOSD).[A214283, A214286] …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +12
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhInebilizumab exhibi…
Vol. DistribusiInebilizumab has an…
KlirensInebilizumab has an…
Genetik -
Inecalcitol DB04796
small molecule | CAS: 163217-09-2

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesFused-Ring Compounds +9
Target Protein:
Vitamin D3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inetetamab DB17457
biotech

Inetetamab is a trastuzumab analog. It differs from trastuzumab by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of trastuzumab.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Infigratinib Approved DB11886
small molecule | CAS: 872511-34-7

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth.[A235174] Cholangiocarcinoma is the most com…

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +24
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3 +1
Waktu ParuhThe geometric mean …
Vol. DistribusiAt steady state, th…
KlirensThe geometric mean …
Genetik -
Infliximab Approved DB00065
biotech | CAS: 170277-31-3

Infliximab is a tumor necrosis factor (TNF-alpha or TNF-?) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. Infliximab is produced by a recombinant cell line cultured by continuous pe…

Kategori:
Agents Causing Muscle ToxicityAgents reducing cytokine levelsAmino Acids, Peptides, and Proteins +21
Target Protein:
Tumor necrosis factor
Gen Terkait:
FCGR3A
Waktu ParuhThe median terminal…
Vol. DistribusiBased on a pharmaco…
KlirensIn patients with Cr…
Genetik 1 Varian
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInfluenza VaccinesLive Attenuated Influenza A Virus Vaccine +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6051–6100 dari 11778
Sebelumnya Halaman 122 / 236 Berikutnya