Hasil Filter

17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (17430)

Halaman 121 / 349
CTR-107 DB18583
biotech

CTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTS-1027 DB08490
small molecule | CAS: 193022-04-7

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.

Kategori:
AminesHydroxy AcidsHydroxylamines
Target Protein:
Stromelysin-1Interstitial collagenase72 kDa type IV collagenase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTS-21166 DB06073
small molecule

CTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far. In 2008, CoMentis revealed this s…

Target Protein:
Beta-secretase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTT-1057 DB14965
small molecule | CAS: 1628717-55-4

CTT-1057 is under investigation in clinical trial NCT03427476 (CTT1057, a Small Molecular Inhibitor of PSMA, as a Novel Imaging Agent of Neovascularization in Renal Cell Carcinoma).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTx-PDE6b DB17858
biotech

CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human _PDE6b_ gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigment…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTX110 DB18626
biotech

CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTX120 DB18625
biotech

CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTX130 DB18627
biotech

CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cu-64 sartate DB18170
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cu-67 sartate DB18698
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cu-Cyclam DB03189
small molecule

Deskripsi belum tersedia.

Target Protein:
Lysozyme C
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cucumber Approved DB10527
biotech

Cucumber allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Cucurbita pepo subsp. ovifera whole allergenic extract is used in allergenic testing.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CUDC-101 DB12174
small molecule | CAS: 1012054-59-9

CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.

Kategori:
AminesAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +5
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cudetaxestat DB18203
small molecule | CAS: 1782070-21-6

Deskripsi belum tersedia.

Target Protein:
Autotaxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Culex pipiens Approved DB14165
biotech

Culex pipiens allergenic extract is used in allergenic testing.

Kategori:
Non-Standardized Insect Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cultivated mushroom Approved DB10544
biotech

Cultivated mushroom allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cumidine DB02114
small molecule | CAS: 99-88-7

Deskripsi belum tersedia.

Kategori:
Amines
Target Protein:
Chymotrypsin-like elastase family member 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cumin Approved DB10864
biotech

Cumin allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cupressus arizonica pollen Approved DB10466
biotech

Cupressus arizonica pollen is the pollen of the Cupressus arizonica plant. Cupressus arizonica pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cupric cation DB14552
small molecule | CAS: 15158-11-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cupric Chloride Approved DB09131
small molecule | CAS: 7447-39-4

Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

Kategori:
ElementsMetalsMetals, Heavy +1
Target Protein:
Vitamin K-dependent protein CCystatin-B
Waktu Paruh-
Vol. DistribusiCopper is distribut…
Klirens-
Genetik -
small molecule | CAS: 13479-54-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cupric oxide Approved DB11134
small molecule | CAS: 1317-38-0

Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-m…

Kategori:
Diet, Food, and NutritionElementsFood +6
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing exposure …
KlirensNo pharmacokinetic …
Genetik -
Cupric sulfate Approved DB06778
small molecule | CAS: 7758-98-7

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4?5H2O) and is also known as _blue vitriol_. The anhydrous salt is created by heating the hydrate t…

Kategori:
AntidotesAutonomic AgentsCentral Nervous System Agents +10
Waktu ParuhThe biological half…
Vol. DistribusiThe body of a 70 kg…
Klirens-
Genetik -
small molecule | CAS: 7758-89-6

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Heavy +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CUR-1916 DB17838
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Curcuma aromatica root oil Approved DB11301
biotech | CAS: 94349-73-2

Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called wild tumeric, via steamed distillation. *Curcuma aromatica* belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its…

Kategori:
Biological ProductsPlant OilsPlant Preparations
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

_Curcuma xanthorrhiza_ oil is extracted from _Curcuma xanthorrhiza_ Roxb., a member of the ginger family (_Zingiberaceae_) that is widely distributed in the region of Southeastern Asia [A33162]. _Curcuma xanthorrhiza_ is also known as Javanese Turmeric or Te…

Waktu ParuhThere are no pharma…
Vol. DistribusiThere are no pharma…
KlirensThere are no pharma…
Genetik -
Curcumin Approved DB11672
small molecule | CAS: 458-37-7

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in [Curcuma xanthorrhiza oil]. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wo…

Kategori:
AlkanesAnalgesicsAnalgesics, Non-Narcotic +29
Target Protein:
Cytochrome P450 3A4Nitric oxide synthase, inducibleCarbonic anhydrase 14 +18
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
small molecule | CAS: 339286-19-0

Deskripsi belum tersedia.

Kategori:
Cytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown)Cytochrome P-450 CYP2B6 Inhibitors +13
Target Protein:
Peroxisome proliferator-activated receptor gammaVitamin D3 receptorATP-binding cassette sub-family C member 5 +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
Curvularia inaequalis Approved DB10697
biotech

Curvularia inaequalis is a fungus which can provoke allergic reactions. Curvularia inaequalis extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cusatuzumab DB15100
biotech | CAS: 1864871-20-4

CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival. An overexpression of CD70 can result in the proliferation of mali…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4
Target Protein:
CD70 antigen
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Custirsen DB05487
biotech | CAS: 890056-27-6

Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis o…

Kategori:
Antisense OligonucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +3
Target Protein:
ClusterinEstrogen receptorNuclear factor NF-kappa-B p100 subunit +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cutamesine DB06618
small molecule | CAS: 165377-43-5

Deskripsi belum tersedia.

Kategori:
Central Nervous System AgentsNootropic AgentsReceptors, sigma, agonists
Target Protein:
Sigma non-opioid intracellular receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CV-8102 DB19184
biotech

CV-8102 is under investigation in clinical trial NCT03203005 (IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CV-MG01 DB16994
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CVac Approved DB17351
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CVN-424 DB18958
small molecule | CAS: 2254706-21-1

CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CVnCoV DB15844
biotech

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CVnCoV Vaccine DB15843
biotech

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CVT-6883 DB05936
small molecule | CAS: 752222-83-6

CVT-6883 is a selective, potent and orally available A2B-adenosine receptor antagonist which CV Therapeutics is investigating for the potential treatment of asthma and other conditions related to inflammation and fibrosis.

Kategori:
Adenosine A2 Receptor AntagonistsHeterocyclic Compounds, Fused-Ring
Target Protein:
Adenosine receptor A2b
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX-046684 Approved DB19414
biotech

CX-046684 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.[L40074]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX-2009 DB16090
biotech | CAS: 2145115-85-9

CX-2009 is under investigation in clinical trial NCT03149549 (PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX-717 DB05047
small molecule | CAS: 867276-98-0

CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.

Target Protein:
Neurotrophic factor BDNF precursor formGlutamate receptor 1Glutamate receptor 2 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX157 DB05205
small molecule

CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor of MAO-A designed to have improved oral bioavailability and reduced clearance compared to previous MAO-A inhibitors of this class.

Target Protein:
Amine oxidase [flavin-containing] A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX501 DB05174
small molecule

Cx501 is used to treat epidermolysis bullosa (EB), a rare genetic condition which can lead to contraction of the joints, fusion of fingers and toes, contraction of the mouth membranes and narrowing of the oesophagus. It is developed by Cellerix and is in phas…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX516 DB06247
small molecule | CAS: 154235-83-3

Deskripsi belum tersedia.

Kategori:
Receptors, AMPA
Target Protein:
Glutamate receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CXA-10 DB15026
small molecule | CAS: 875685-46-4

CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)).

Kategori:
Anti-Inflammatory AgentsFatty AcidsFatty Acids, Monounsaturated +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CXD101 DB16182
small molecule | CAS: 934828-12-3

CXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 6001–6050 dari 17430
Sebelumnya Halaman 121 / 349 Berikutnya