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11793

Total database: 17430
Struktur (SMILES)
8607 (73.0%)
Target
6418 (54.4%)
Genomik
102 (0.9%)
Referensi
11793 (100.0%)

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Halaman 121 / 236
Indalpine DB08953
small molecule | CAS: 63758-79-2

Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematologica…

Kategori:
Antidepressive AgentsCentral Nervous System AgentsCentral Nervous System Depressants +16
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indanazoline DB13827
small molecule | CAS: 40507-78-6

Deskripsi belum tersedia.

Kategori:
Nasal PreparationsSympathomimetics, Plain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 14Carbonic anhydrase 12 +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indantadol DB12664
small molecule | CAS: 202844-10-8

Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsIndenes +1
Target Protein:
Amine oxidase [flavin-containing] BAmine oxidase [flavin-containing] A
Waktu Paruh-
Vol. Distribusi-
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Indapamide Approved DB00808
small molecule | CAS: 26807-65-8

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension.[A204155] Characterized by an office blood pressure of ?140/90, hypertension is pervasive and impacts an estimated…

Kategori:
AmidesAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension +26
Target Protein:
Solute carrier family 12 member 3Potassium voltage-gated channel subfamily KQT member 1
Waktu ParuhIndapamide is chara…
Vol. DistribusiSome sources report…
KlirensIndapamide's renal …
Genetik -
Indatraline DB17032
small molecule | CAS: 86939-10-8

Indatraline is a nonselective monoamine reuptake inhibitor.[A253022]

Kategori:
AminesIndenes
Target Protein:
Sodium-dependent dopamine transporter
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech | CAS: 1238517-16-2

Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAntibodies +10
Waktu Paruh-
Vol. Distribusi-
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Indeglitazar DB07724
small molecule | CAS: 835619-41-5

Deskripsi belum tersedia.

Target Protein:
Peroxisome proliferator-activated receptor alphaPeroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor delta +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indenolol DB08952
small molecule | CAS: 60607-68-3

Indenolol is a drug of the beta-adrenergic blocker class.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indibulin DB06169
small molecule | CAS: 204205-90-3

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indigo DB16862
small molecule | CAS: 482-89-3

Deskripsi belum tersedia.

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Aryl hydrocarbon receptor
Waktu Paruh-
Vol. Distribusi-
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Indigotindisulfonic acid Approved DB11577
small molecule | CAS: 483-20-5

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in …

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingDiagnostic Agents +5
Target Protein:
Alpha adrenergic receptor
Waktu ParuhIn healthy adults g…
Vol. DistribusiThe volume of distr…
KlirensIn healthy adults g…
Genetik -
Indirubin DB12379
small molecule | CAS: 479-41-4

Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).

Kategori:
Antibiotics, AntineoplasticAntineoplastic AgentsColoring Agents +4
Target Protein:
Cytochrome P450 1A1Aryl hydrocarbon receptor
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 244021-67-8

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle formCell division control protein 2 homolog
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indisulam DB06370
small molecule | CAS: 165668-41-7

Deskripsi belum tersedia.

Kategori:
AmidesAntineoplastic AgentsCarbonic Anhydrase Inhibitors +15
Target Protein:
Carbonic anhydrase 9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium DB11659
small molecule | CAS: 7440-74-6

Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma.

Kategori:
AnionsElectrolytesElements +5
Waktu Paruh-
Vol. Distribusi-
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Indium In-111 DB11916
small molecule | CAS: 15750-15-9

Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).

Waktu Paruh-
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Genetik -
biotech | CAS: 156586-92-4

Deskripsi belum tersedia.

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Indium In-111 chloride Approved DB09490
small molecule | CAS: 50800-85-6

Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxeta…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh2.8 days
Vol. DistribusiIndium In-111 Chlor…
KlirensIndium In-111 Chlor…
Genetik -
biotech | CAS: 138661-00-4

Indium In-111 imciromab pentetate is a mouse monoclonal antibody labelled with the radioisotope Indium-111 which was used for cardiac imaging under the trade name Myoscint, but was withdrawn in 1993.

Kategori:
Diagnostic Radiopharmaceuticals
Waktu Paruh-
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Indium In-111 oxyquinoline Approved DB09473
small molecule | CAS: 65389-08-4

Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron ca…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu ParuhIndium In 111 decay…
Vol. Distribusi-
KlirensClearance from whol…
Genetik -
Indium In-111 pentetreotide Approved DB11835
small molecule | CAS: 139096-04-1

Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic RadiopharmaceuticalsHormones +14
Waktu Paruh-
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Genetik -
small molecule | CAS: 139096-04-1

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic Agent
Waktu Paruh-
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Genetik -
Indobufen DB12545
small molecule | CAS: 63610-08-2

Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16
Waktu Paruh-
Vol. Distribusi-
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Indocyanine green Approved DB16024
small molecule | CAS: 3599-32-4

Deskripsi belum tersedia.

Kategori:
Cardiac FunctionColoring AgentsCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indocyanine green acid form Approved DB09374
small molecule | CAS: 28782-33-4

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl…

Kategori:
BSEP/ABCB11 SubstratesCardiac FunctionColoring Agents +6
Waktu ParuhICG has a half-life…
Vol. DistribusiICG distribution in…
KlirensClearance of dyes w…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Waktu Paruh-
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Genetik -
small molecule | CAS: 700-06-1

Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsCompounds used in a research, industrial, or household setting +2
Target Protein:
NF-kappa-B inhibitor alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indoleacetamide DB08652
small molecule | CAS: 879-37-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Target Protein:
Aralkylamine dehydrogenase light chainAralkylamine dehydrogenase heavy chain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 830-96-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +2
Target Protein:
Group IIE secretory phospholipase A2Aspartate aminotransferaseAromatic-amino-acid aminotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indomethacin Approved DB00328
small molecule | CAS: 53-86-1

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an ind…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +49
Target Protein:
Prostaglandin G/H synthase 2Phospholipase A2, membrane associatedHuman Cyclooxygenases +8
Waktu ParuhIndometacin disposi…
Vol. DistribusiThe volume of distr…
KlirensIn a clinical pharm…
Genetik -
Indopan DB01446
small molecule | CAS: 299-26-3

Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use a…

Kategori:
AminesBiogenic AminesBiogenic Monoamines +3
Waktu Paruh-
Vol. Distribusi-
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Indoramin Approved DB08950
small molecule | CAS: 26844-12-2

Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.

Kategori:
Acids, CarbocyclicAdrenergic AgentsAdrenergic alpha-1 Receptor Antagonists +16
Target Protein:
Alpha-1D adrenergic receptorAlpha-2C adrenergic receptorAlpha-2B adrenergic receptor +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indotecan DB18752
small molecule | CAS: 915303-09-2

Deskripsi belum tersedia.

Kategori:
DioxolesDNA Topoisomerases, Type IHeterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Indralin DB18220
small molecule | CAS: 156691-86-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesReceptors, Retinoic Acid, agonistsSulfur Compounds
Waktu Paruh-
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Genetik -
Inebilizumab Approved DB12530
biotech | CAS: 1299440-37-1

Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOSD).[A214283, A214286] …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +12
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhInebilizumab exhibi…
Vol. DistribusiInebilizumab has an…
KlirensInebilizumab has an…
Genetik -
Inecalcitol DB04796
small molecule | CAS: 163217-09-2

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesFused-Ring Compounds +9
Target Protein:
Vitamin D3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Infigratinib Approved DB11886
small molecule | CAS: 872511-34-7

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth.[A235174] Cholangiocarcinoma is the most com…

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +24
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3 +1
Waktu ParuhThe geometric mean …
Vol. DistribusiAt steady state, th…
KlirensThe geometric mean …
Genetik -
Infliximab Approved DB00065
biotech | CAS: 170277-31-3

Infliximab is a tumor necrosis factor (TNF-alpha or TNF-?) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. Infliximab is produced by a recombinant cell line cultured by continuous pe…

Kategori:
Agents Causing Muscle ToxicityAgents reducing cytokine levelsAmino Acids, Peptides, and Proteins +21
Target Protein:
Tumor necrosis factor
Gen Terkait:
FCGR3A
Waktu ParuhThe median terminal…
Vol. DistribusiBased on a pharmaco…
KlirensIn patients with Cr…
Genetik 1 Varian
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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