Hasil Filter

14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
Referensi
14494 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (14494)

Halaman 120 / 290
Ethacizine DB13645
small molecule | CAS: 33414-33-4

Deskripsi belum tersedia.

Kategori:
Antiarrhythmic agentsAntiarrhythmics, Class IAntiarrhythmics, Class Ic +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethacridine DB13190
small molecule | CAS: 442-16-0

Deskripsi belum tersedia.

Kategori:
Acridine DerivativesAcridinesAminoacridines +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethambutol Approved DB00330
small molecule | CAS: 74-55-5

Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis.[L31743] Ethambutol was first described in the literature in 1961.[A229048] It was developed ou…

Kategori:
AminesAnti-Bacterial AgentsAnti-Infective Agents +23
Target Protein:
Probable arabinosyltransferase CProbable arabinosyltransferase BProbable arabinosyltransferase A
Waktu ParuhEthambutol has a ha…
Vol. DistribusiPatients coinfected…
KlirensPatients coinfected…
Genetik -
small molecule | CAS: 594-45-6

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsHydrocarbons, Acyclic +3
Target Protein:
Platelet basic proteinPhosphonoacetaldehyde hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethanol Approved DB00898
small molecule | CAS: 64-17-5

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical prepara…

Kategori:
Agents Causing Muscle ToxicityAlcoholsAnti-Infective Agents +34
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Glutamate receptor ionotropic, NMDA 3AGlycine receptor subunit alpha-1 +51
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethanolamine DB03994
small molecule | CAS: 141-43-5

A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.

Kategori:
AlcoholsAminesAmino Alcohols +4
Target Protein:
Surface protein AAnnexin A3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethanolamine oleate Approved DB06689
small molecule | CAS: 2272-11-9

Ethanolamine oleate is a mild sclerosing agent. It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.

Kategori:
Antivaricose TherapyCardiovascular AgentsCompounds used in a research, industrial, or household setting +10
Target Protein:
Calcium ionsCoagulation factor XII
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethaselen DB15051
small molecule | CAS: 217798-39-5

Ethaselen is under investigation in clinical trial NCT02166242 (Ethaselen for the Treatment of Thioredoxin Reductase High Expression Advanced Non-small Cell Lung Cancers).

Kategori:
Selenium Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethchlorvynol Approved DB00189
small molecule | CAS: 113-18-8

Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.

Kategori:
AlcoholsCentral Nervous System AgentsCentral Nervous System Depressants +4
Target Protein:
Gamma-aminobutyric acid receptor subunit beta-2Gamma-aminobutyric acid receptor subunit alpha-1GABA(A) Receptor
Waktu ParuhPlasma half-life is…
Vol. Distribusi-
Klirens-
Genetik -
Ethinamate Approved DB01031
small molecule | CAS: 126-52-3

Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally …

Kategori:
Acids, Acyclic
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh2.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethinylestradiol Approved DB00977
small molecule | CAS: 57-63-6

Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.[A191107] These properties were achieved by the substitution…

Kategori:
Adrenal Cortex HormonesAntineoplastic and Immunomodulating AgentsBSEP/ABCB11 inducers +48
Target Protein:
Estrogen receptorNuclear receptor subfamily 1 group I member 2
Waktu ParuhA 30µg oral dose ha…
Vol. DistribusiA 30µg oral dose ha…
KlirensEthinylestradiol ha…
Genetik -
Ethiodized oil Approved DB00965
small molecule | CAS: 8008-53-5

Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl dii…

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethionamide Approved DB00609
small molecule | CAS: 536-33-4

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiinfectives for Systemic Use +9
Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]Nuclear factor erythroid 2-related factor 2Catalase-peroxidase
Waktu Paruh2 to 3 hours
Vol. Distribusi* 93.5 L [healthy v…
Klirens-
Genetik -
Ethoheptazine Approved DB08988
small molecule | CAS: 77-15-6

Ethoheptazine is marketed under the name Zactane. It is a phenazepine based opioid analgesic. It was invented in the 1950s and is related to other drugs such as proheptazine. Ethoheptazine is no longer marketed in the United States.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethosuximide Approved DB00593
small molecule | CAS: 77-67-8

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

Kategori:
Agents causing hyperkalemiaAnti-epileptic AgentAntiarrhythmic agents +18
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1G
Waktu Paruh53 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethotoin Approved DB00754
small molecule | CAS: 86-35-1

Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabili…

Kategori:
Anti-epileptic AgentAnticonvulsantsCardiovascular Agents +14
Target Protein:
Sodium channel protein type 5 subunit alphaNuclear receptor subfamily 1 group I member 2
Waktu Paruh3 to 9 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethoxzolamide DB00311
small molecule | CAS: 452-35-7

Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypoka…

Kategori:
AmidesBenzothiazolesCarbonic Anhydrase Inhibitors +9
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 4Carbonic anhydrase 7 +2
Waktu Paruh2.5-5.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15400-53-0

Deskripsi belum tersedia.

Target Protein:
Dihydroneopterin aldolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Dual specificity protein kinase CLK1Dual specificity tyrosine-phosphorylation-regulated kinase 1ADual specificity protein kinase CLK3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducible
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducibleNitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 686723-15-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 548-00-5

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

Kategori:
4-HydroxycoumarinsAnticoagulantsBenzopyrans +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl butyrate DB15454
small molecule | CAS: 105-54-4

Ethyl butyrate is under investigation in clinical trial NCT03202342 (fMRI of Hypothalamic Responses to Taste, Temperature and Glucose).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl chloride Approved DB13259
small molecule | CAS: 75-00-3

Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the…

Kategori:
AnestheticsAnesthetics, LocalCentral Nervous System Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1623-14-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +7
Target Protein:
CholinesteraseParathion hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl ferulate Approved DB11285
small molecule | CAS: 4046-02-0

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicCinnamates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl hydroxybenzoate Approved DB13628
small molecule | CAS: 120-47-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAntifungals for Dermatological UseAntifungals for Topical Use +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Myoglobin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29177-84-2

Deskripsi belum tersedia.

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepines and benzodiazepine derivatives +7
Target Protein:
GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl macadamiate Approved DB11243
small molecule

Ethyl macadamiate is derived from Macadamia terifolia seed oil. It is a non-volatile ester of ethyl alcohol and the fatty acids. Ethyl macadamiate is used in cosmetics and personal care products such as sunscreen, hair care products and skin care products as …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24393-56-4

Deskripsi belum tersedia.

Kategori:
Sunscreen Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 105-40-8

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCarbamates
Target Protein:
Shiga-like toxin 1 subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl nitrite DB16560
small molecule | CAS: 109-95-5

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIons +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 53074-96-7

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 41653-21-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl pyruvate DB05869
small molecule | CAS: 617-35-6

CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-rep…

Kategori:
Keto Acids
Target Protein:
Tumor necrosis factorHigh mobility group protein B1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl salicylate Approved DB15576
small molecule | CAS: 118-61-6

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Shiga-like toxin 1 subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Candidapepsin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 107-06-2

Deskripsi belum tersedia.

Kategori:
AlkanesEthaneHydrocarbons, Acyclic +2
Target Protein:
Haloalkane dehalogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylenediamine Approved DB14189
small molecule | CAS: 107-15-3

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer c…

Kategori:
AllergensAminesAntigens +6
Target Protein:
Dihydropteroate synthase
Waktu ParuhEthylenediamine has…
Vol. DistribusiVd = 0.133 l/kg [A3…
Klirens-
Genetik -
Ethylestrenol DB01493
small molecule | CAS: 965-90-2

An anabolic steroid with some progestational activity and little androgenic effect. [PubChem]

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +9
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylhexyl methoxycrylene Approved DB11226
small molecule | CAS: 947753-66-4

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states [F104]. It returns UV filters to their ground states without absorbing sunlight [F104]. It is used as a solve…

Waktu ParuhEthylhexyl methoxyc…
Vol. DistribusiEthylhexyl methoxyc…
KlirensEthylhexyl methoxyc…
Genetik -
small molecule | CAS: 70445-33-9

An emollient solvent with antimicrobial activity.

Kategori:
AlcoholsEthersSugar Alcohols +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 148-61-8

Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.

Target Protein:
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialSensor histidine kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylmorphine DB01466
small molecule | CAS: 76-58-4

A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a sched…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +22
Target Protein:
Mu-type opioid receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethynodiol diacetate Approved DB00823
small molecule | CAS: 297-76-7

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacet…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +19
Target Protein:
Progesterone receptorEstrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 5951–6000 dari 14494
Sebelumnya Halaman 120 / 290 Berikutnya