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6694

Total database: 17430
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4518 (67.5%)
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3751 (56.0%)
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81 (1.2%)
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6694 (100.0%)

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Halaman 118 / 134
biotech

Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 6a individually conjugated to the CRM197 protei…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 6b capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 6b of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcut…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 6b individually conjugated to the CRM197 protei…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 7f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 7f of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcut…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 7F individually conjugated to the CRM197 protei…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 8 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 8 of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcutan…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 8 individually conjugated to the CRM197 protein,…

Kategori:
Inactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 9n capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9n of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcut…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 9N capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of _Streptococcus pneumoniae_ serotype 9N individually conjugated to the CRM197 protei…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 9v capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9v of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcut…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 9v individually conjugated to the CRM197 protei…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type deOAc15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains de-O-acetylated saccharides of the capsular antigens of _Streptococcus pneumoniae_ serotype 15B individually conjugat…

Waktu Paruh-
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Genetik -
Streptokinase Approved DB00086
biotech | CAS: 9002-01-1

Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +15
Target Protein:
PlasminogenProteinase-activated receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Streptolydigin DB04785
small molecule | CAS: 7229-50-7

Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsCarbohydrates +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Streptomycin Approved DB01082
small molecule | CAS: 57-92-1

Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAminoglycoside Antibacterials +16
Target Protein:
16S ribosomal RNA23S ribosomal RNA30S ribosomal protein S12 +3
Waktu ParuhStreptomycins serum…
Vol. Distribusi-
Klirens-
Genetik -
Streptozocin Approved DB00428
small molecule | CAS: 18883-66-4

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

Kategori:
Alkylating ActivityAlkylating DrugsAmides +18
Target Protein:
O-GlcNAcase BT_4395DNASolute carrier family 2, facilitated glucose transporter member 2 +1
Waktu Paruh5-15 minutes
Vol. Distribusi-
Klirens-
Genetik -
STRO-001 DB17224
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Strontium chloride Approved DB13987
small molecule | CAS: 10476-85-4

Strontium chloride (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. This…

Kategori:
Drugs that are Mainly Renally ExcretedElementsMetals +3
Waktu ParuhReadily accessible …
Vol. DistribusiThe distribution of…
KlirensDespite being the m…
Genetik -
Strontium chloride Sr-89 Approved DB09498
small molecule | CAS: 38270-90-5

Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer.[A31264] Bone meta…

Kategori:
ElementsMetalsMetals, Alkaline Earth +6
Waktu ParuhStrontium chloride …
Vol. DistribusiThere have been sev…
KlirensStrontium chloride …
Genetik -
Strontium ranelate Approved DB09267
small molecule | CAS: 135459-87-9

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in wh…

Kategori:
Bone Density Conservation AgentsDrugs Affecting Bone Structure and MineralizationDrugs for Treatment of Bone Diseases +3
Waktu ParuhThe effective half-…
Vol. DistribusiStrontium has a vol…
KlirensThe plasma dclearan…
Genetik -
Subasumstat DB16406
small molecule | CAS: 1858276-04-6

Subasumstat is under investigation in clinical trial NCT03648372 (A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Advanced or Metastatic Solid Tumors or Relapsed/refractory Hem…

Kategori:
Experimental Unapproved Treatments for COVID-19Heterocyclic Compounds, Fused-RingSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succimer Approved DB00566
small molecule | CAS: 304-55-2

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Kategori:
Acids, AcyclicAntidotesChelating Agents +9
Target Protein:
LeadMercuryCadmium +1
Waktu Paruh48 hours
Vol. Distribusi-
Klirens-
Genetik -
Succinamide-CoA DB03905
small molecule

Deskripsi belum tersedia.

Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinic acid Approved DB00139
small molecule | CAS: 110-15-6

A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condens…

Kategori:
Acids, AcyclicDicarboxylic AcidsDietary Supplements +3
Target Protein:
Succinate-semialdehyde dehydrogenase, mitochondrialSuccinate receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Steroid Delta-isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinimide DB13376
small molecule | CAS: 123-56-8

Deskripsi belum tersedia.

Kategori:
Genito Urinary System and Sex HormonesImidesPyrrolidines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinobucol DB05399
small molecule | CAS: 216167-82-7

AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.

Kategori:
Benzene DerivativesPhenols
Target Protein:
Vascular cell adhesion protein 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 604-98-8

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 68915-24-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino Acids, Peptides, and ProteinsDicarboxylic Acids +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinylcholine Approved DB00202
small molecule | CAS: 306-40-1

Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.[A19054] It has been widely used for over 50 years,[A299] most commonly in its chlori…

Kategori:
Acids, AcyclicAgents causing hyperkalemiaAmines +20
Target Protein:
Neuronal Acetylcholine (nACh) Receptor SubunitsMuscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3
Waktu ParuhThe mean half-life …
Vol. DistribusiAt intravenous dose…
KlirensThe mean _in vivo_ …
Genetik -
small molecule | CAS: 116-43-8

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmidesAmines +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucralfate Approved DB00364
small molecule | CAS: 54182-58-0

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to …

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Complex +14
Target Protein:
Pepsin A-5Fibroblast growth factor 2Pro-epidermal growth factor +1
Waktu ParuhThe half-life is no…
Vol. DistribusiThis drug is absorb…
KlirensSucralfate contains…
Genetik -
Sucralose DB15049
small molecule | CAS: 56038-13-2

Sucralose is an artificial sweetener used as a sugar substitute.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucrose Approved DB02772
small molecule | CAS: 57-50-1

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +12
Target Protein:
Beta-lactamaseTaste receptor type 1 member 2Beta-lactamase +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sugammadex Approved DB06206
small molecule | CAS: 343306-71-8

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause …

Kategori:
AntidotesCarbohydratesCompounds used in a research, industrial, or household setting +6
Waktu ParuhAbout 2 hours
Vol. DistribusiAt steady state, th…
Klirens88L/min
Genetik -
Sugemalimab DB16641
biotech | CAS: 2256084-03-2

Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell ly…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbactam Approved DB09324
small molecule | CAS: 68373-14-8

Sulbactam is a beta (?)-lactamase inhibitor and a derivative of the basic penicillin nucleus.[L50131] When given in combination with ?-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydro…

Kategori:
AmidesAnti-Infective AgentsAntibacterials for Systemic Use +10
Target Protein:
Beta-lactamase
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe steady-state vo…
KlirensEenal clearance is …
Genetik -
Sulbenicillin DB13693
small molecule | CAS: 41744-40-5

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulconazole Approved DB06820
small molecule | CAS: 61318-90-9

Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +11
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 80-32-0

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Kategori:
AmidesAminesAniline Compounds +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfacytine Approved DB01298
small molecule | CAS: 17784-12-2

Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamide…

Kategori:
AmidesAminesAniline Compounds +5
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadiazine Approved DB00359
small molecule | CAS: 68-35-9

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Kategori:
AmidesAminesAniline Compounds +29
Target Protein:
Dihydropteroate synthetaseDihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadimethoxine Approved DB06150
small molecule | CAS: 122-11-2

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved…

Kategori:
AmidesAminesAniline Compounds +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 515-64-0

Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been officially approved for use anywhere [A175672].

Kategori:
AmidesAminesAniline Compounds +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethoxazole Approved DB01015
small molecule | CAS: 723-46-6

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.[L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis…

Kategori:
Agents causing hyperkalemiaAgents Causing Muscle ToxicityAmines +39
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe average serum h…
Vol. DistribusiThe volume of distr…
KlirensThe oral and renal …
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carbonic anhydrase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanilamide Approved DB00259
small molecule | CAS: 63-74-1

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.

Kategori:
AmidesAminesAniline Compounds +21
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 59-40-5

Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as potential treatment of coccidiosis.

Kategori:
AmidesAminesAniline Compounds +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfasalazine Approved DB00795
small molecule | CAS: 599-79-1

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metab…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +23
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2Transcription factor RelBTranscription factor p65 +12
Waktu ParuhThe observed plasma…
Vol. DistribusiFollowing intraveno…
KlirensThe calculated clea…
Genetik -
Sulfate ion DB14546
small molecule | CAS: 14808-79-8

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIncreased Large Intestinal Motility +9
Target Protein:
Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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