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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (11778)

Halaman 117 / 236
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin F
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small molecule | CAS: 1192-20-7

Deskripsi belum tersedia.

Kategori:
FuransLactonesLuminescent Proteins
Target Protein:
Sodium/hydrogen exchanger 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Thermolysin
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Honokiol DB19283
small molecule | CAS: 35354-74-6

Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).

Kategori:
AlkenesAnti-Allergic AgentsAnti-Anxiety Agents +24
Target Protein:
Polyunsaturated fatty acid 5-lipoxygenaseProstaglandin G/H synthase 1Prostaglandin G/H synthase 2
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Hopantenic acid DB14044
small molecule | CAS: 18679-90-8

Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115]

Kategori:
Acids, AcyclicAlanineAmino Acids +6
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Hops Approved DB10687
biotech

Hops allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityHerbs and Natural ProductsIncreased Histamine Release +2
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Horse chestnut DB13195
biotech

Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are pro…

Kategori:
AngiospermsBiological ProductsCapillary Stabilizing Agents +12
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Horseradish Approved DB10674
biotech

Horseradish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
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HOV-12020 DB17976
small molecule

HOV-12020 is a palm tocotrienols complex being investigated for the treatment of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).[L47271]

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HPA-23 DB17739
small molecule | CAS: 89899-81-0

HPA-23 is an investigational antiviral compound.[A259142]

Kategori:
Anti-Infective AgentsAntineoplastic AgentsAntiviral Agents +4
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biotech

HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.

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HQP1351 DB16185
small molecule | CAS: 1257628-77-5

HQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
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HRS-1167 DB18703
small molecule

HRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).

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HSK-3486 DB16295
small molecule | CAS: 1637741-58-2

HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).

Kategori:
Benzene Derivatives
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HT-0712 DB11650
small molecule | CAS: 617720-02-2

BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).

Kategori:
Piperidines
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B
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HT-KIT DB18467
biotech

Deskripsi belum tersedia.

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HTPEP-001 DB18730
biotech

HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-?). It is being investigated for the treatment of fibrosis.[A263527]

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Hu-PHEC Liver DB18347
biotech

Hu-PHEC Liver is an adult hemogenic endothelial cells.

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biotech

Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the treatment of advanced non-small cell lung canc…

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hu3S193 DB17213
biotech

Deskripsi belum tersedia.

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biotech

Human adenovirus b serotype 7 is a vaccine.

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biotech

Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.

Kategori:
Actively Acquired ImmunityAdenovirus VaccinesLive Human Adenovirus Type 4 Vaccine +3
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biotech

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biotech

Human amniotic fluid is the liquid surrounding the human embryo and fetus.[L16373] Physically, the fluid provides protection through cushioning. Chemically, the fluid provides protection through its inherent antibacterial properties. The fluid contains carboh…

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biotech | CAS: 1822383-06-1

Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus Erythematosus).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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small molecule

Deskripsi belum tersedia.

Kategori:
AntigensAntigens, NeoplasmBiological Factors +3
Target Protein:
Histo-blood group ABO system transferase
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Human calcitonin Approved DB06773
biotech | CAS: 21215-62-3

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.[A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus …

Kategori:
Bone Density Conservation AgentsCalcitonin PreparationsCalcium Homeostasis +1
Target Protein:
Alpha-actinin-1
Waktu ParuhIntravenous adminis…
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KlirensThe metabolic clear…
Genetik -
biotech

Human ciliary neurotrophic factor, recombinant was investigated for macular telangiectasia in two clinical trials. The trials were NCT03071965, an extension study of the NT-501 CNTF implant for macular telangiectasia, and NCT01949324, a Phase 2 multicenter ra…

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biotech

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biotech

CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are curre…

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biotech | CAS: 259230-56-3

Human growth hormone-releasing peptide 3 is under investigation in clinical trial NCT00846872 (Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance).

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Human immunoglobulin G Approved DB00028
biotech | CAS: 308067-58-5

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatogra…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntigen Neutralization +13
Target Protein:
High affinity immunoglobulin gamma Fc receptor IPutative high affinity immunoglobulin gamma Fc receptor IBLow affinity immunoglobulin gamma Fc region receptor II-a +8
Waktu Paruh>20 hours (mammalia…
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Human interferon beta Approved DB14999
biotech | CAS: 74899-71-1

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992.[L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and s…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsBiological Factors +7
Target Protein:
Interferon alpha/beta receptor 1
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe average state v…
KlirensAverage serum clear…
Genetik -
biotech

Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are m…

Kategori:
Immunosuppressive AgentsMyelosuppressive Agents
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
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biotech

Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).

Kategori:
Amino Acids, Peptides, and ProteinsAnalgesicsAnalgesics, Non-Narcotic +12
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biotech

Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
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biotech

Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner …

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biotech

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biotech

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biotech

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biotech

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Human Rho(D) immune globulin Approved DB11597
biotech

Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilize…

Kategori:
Amino Acids, Peptides, and ProteinsAntiinfectives for Systemic UseBlood Proteins +9
Target Protein:
Rhesus blood group D antigen
Waktu ParuhThe half life is 16…
Vol. DistribusiA single dose of 30…
KlirensMean systemic clear…
Genetik -
Human thrombin Approved DB11571
biotech | CAS: 9002-04-4

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This tra…

Kategori:
Blood Coagulation FactorsIncreased Coagulation Factor Activity
Target Protein:
Coagulation factor VCoagulation factor VIIICoagulation factor XI +5
Waktu ParuhDue to the nature o…
Vol. DistribusiDue to the nature o…
KlirensDue to the nature o…
Genetik -
biotech

Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines thes…

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biotech

Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marro…

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biotech

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biotech

Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +10
Waktu ParuhThe mean half-life …
Vol. DistribusiThe volume of distr…
KlirensReadily accessible …
Genetik -
biotech

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biotech

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Humate-P DB17966
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +4
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