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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

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Hasil Pencarian (11778)

Halaman 116 / 236
Hepcidin-25 DB19226
biotech | CAS: 1356390-47-0

Hepcidin-25 is under investigation in clinical trial NCT03381833 (A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-dependent Beta Thalassemia).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

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Genetik -
HEPES DB16872
small molecule | CAS: 7365-45-9

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsBuffers +7
Waktu Paruh-
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Genetik -
small molecule | CAS: 5617-32-3

Deskripsi belum tersedia.

Kategori:
Pegylated agents
Target Protein:
Carbonyl reductase [NADPH] 1
Waktu Paruh-
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Genetik -
Heptaminol DB13574
small molecule | CAS: 372-66-7

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsLipids
Target Protein:
RhodopsinFimbrial proteinFe(3+) dicitrate transport protein FecA
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 78617-12-6

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase FKBP1APeroxisome proliferator-activated receptor delta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HER-902 DB17948
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Herring Approved DB10617
biotech

Herring allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
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Genetik -
Hesperetin DB01094
small molecule | CAS: 520-33-2

Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.

Kategori:
BCRP/ABCG2 InhibitorsBenzopyransCarbohydrates +8
Target Protein:
Diacylglycerol O-acyltransferase 1Microsomal triglyceride transfer protein large subunitSterol O-acyltransferase 1 +2
Waktu Paruh-
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Genetik -
Hesperidin Approved DB04703
small molecule | CAS: 520-26-3

Hesperidin is a flavan-on glycoside found in citrus fruits.

Kategori:
BenzopyransCarbohydratesChromones +5
Target Protein:
Voltage-dependent N-type calcium channel subunit alpha-1BAurora kinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetacillin Approved DB00739
small molecule | CAS: 3511-16-8

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of ant…

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +8
Target Protein:
Penicillin-binding protein 2aPenicillin-binding protein 1bPenicillin-binding protein 3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

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Genetik -
Hetrombopag DB16184
small molecule | CAS: 1257792-41-8

Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).

Kategori:
HydrazinesPyrazoles
Waktu Paruh-
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Hexachlorophene Approved DB00756
small molecule | CAS: 70-30-4

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorder…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +8
Target Protein:
D-lactate dehydrogenaseSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialGlutamate dehydrogenase 1, mitochondrial +1
Waktu Paruh-
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Genetik -
small molecule | CAS: 86855-26-7

Deskripsi belum tersedia.

Kategori:
Fatty AcidsLipidsPalmitic Acids +1
Target Protein:
Palmitoyl-protein thioesterase 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 29710-31-4

Deskripsi belum tersedia.

Target Protein:
HTH-type transcriptional regulator EthR
Waktu Paruh-
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Klirens-
Genetik -
Hexamidine Approved DB03808
small molecule | CAS: 3811-75-4

Deskripsi belum tersedia.

Kategori:
AmidinesAnti-Infective AgentsAnti-Infective Agents, Local +8
Target Protein:
HTH-type transcriptional regulator QacRHTH-type transcriptional regulator QacR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexaminolevulinate Approved DB06261
small molecule | CAS: 140898-97-1

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approv…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsCarbon Radioisotopes +5
Waktu ParuhBiphasic eliminatio…
Vol. Distribusi-
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Genetik -
Hexapeptide-2 DB18238
biotech | CAS: 87616-84-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsGrowth Hormone-Releasing HormonePeptides
Waktu Paruh-
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Genetik -
small molecule | CAS: 34367-89-0

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesInositol Phosphates +2
Waktu Paruh-
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Genetik -
Hexestrol DB07931
small molecule | CAS: 84-16-2

A synthetic estrogen that has been used as a hormonal antineoplastic agent.

Kategori:
Antineoplastic AgentsAntineoplastic Agents, HormonalBenzene Derivatives +11
Target Protein:
Aldo-keto reductase family 1 member C1Estrogen receptorNuclear receptor subfamily 1 group I member 2 +1
Waktu Paruh-
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Klirens-
Genetik -
Hexobendine Approved DB13265
small molecule | CAS: 54-03-5

Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478].

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Waktu Paruh-
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Hexocyclium Approved DB06787
small molecule | CAS: 6004-98-4

Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. Proton pump inhibitors lik…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAnticholinergic Agents +3
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2 +1
Waktu Paruh-
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Hexoprenaline DB08957
small molecule | CAS: 3215-70-1

Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +18
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Hexylcaine Approved DB00473
small molecule | CAS: 532-77-4

Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mout…

Kategori:
AminesCyclohexanesCycloparaffins
Target Protein:
Sodium channel protein type 5 subunit alphaSodium channel protein type 10 subunit alpha
Waktu Paruh<10 minutes
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Genetik -
Hexylresorcinol Approved DB11254
small molecule | CAS: 136-77-6

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid …

Kategori:
AnthelminticsAnti-Infective AgentsAnti-Infective Agents, Local +6
Target Protein:
TyrosinaseDNA topoisomerase 1Protein-glutamine gamma-glutamyltransferase 2
Waktu ParuhReadily accessible …
Vol. DistribusiReadily accessible …
KlirensReadily accessible …
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Waktu Paruh-
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Genetik -
HGTV-43 DB05807
biotech

HGTV43 is an anti-sense treatment designed to produce T cells that are genetically resistant to HIV infection. HGTV43 is one of a number of so-called 'gene transfer vectors' developed by the biotechnology company Enzo Biochem, Inc.

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HH-009 DB18727
biotech

HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.

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Higenamine DB12779
small molecule | CAS: 5843-65-2

Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-Agonists +17
Waktu Paruh-
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Hiltonol DB17293
biotech | CAS: 59789-29-6

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAmino AcidsAmino Acids, Basic +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hispidulin DB14008
small molecule | CAS: 1447-88-7

Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties [A32513].

Kategori:
BenzopyransChromonesFlavonoids +2
Waktu Paruh-
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Genetik -
small molecule | CAS: 1464897-15-1

Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).

Kategori:
AminesAnti-Asthmatic AgentsAutacoids +6
Waktu Paruh-
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Histapyrrodine DB13479
small molecule | CAS: 493-80-1

Deskripsi belum tersedia.

Kategori:
Antihistamines for Systemic UseSubstituted Ethylene Diamines
Waktu Paruh-
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Histidine DB00117
small molecule | CAS: 71-00-1

An essential amino acid that is required for the production of histamine.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Essential +4
Target Protein:
Histidine decarboxylaseHistidine--tRNA ligase, cytoplasmicSodium-coupled neutral amino acid transporter 3 +1
Waktu Paruh-
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Genetik -
Histrelin Approved DB06788
small molecule | CAS: 76712-82-8

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher pot…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +17
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe apparent volume…
KlirensIn prostate cancer …
Genetik -
small molecule | CAS: 729607-74-3

HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +5
Waktu Paruh-
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Genetik -
HKI-357 DB13002
small molecule | CAS: 848133-17-5

Hki 357 is under investigation in clinical trial NCT00550381 (Study Evaluating the Safety, Tolerability, and Pharmacokinetics (PK) of HKI-357 Administered Orally to Healthy Subjects).

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HL001 DB18026
small molecule | CAS: 1186371-31-2

Deskripsi belum tersedia.

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HLX70 DB16509
biotech

HLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics in healthy adult volunteers. The condition …

Kategori:
Experimental Unapproved Treatments for COVID-19
Waktu Paruh-
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HM-30181 DB14070
small molecule | CAS: 849675-66-7

Deskripsi belum tersedia.

Kategori:
ATP Binding Cassette Transporter, Subfamily B, Member 1, antagonists & inhibitorsHeterocyclic Compounds, Fused-RingP-glycoprotein inhibitors +1
Target Protein:
ATP-dependent translocase ABCB1Phosphatidylcholine translocator ABCB4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HMI-103 DB17684
biotech

HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.

Waktu Paruh-
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HMR4011 DB06225
small molecule

HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. IPL 576,092 has previously been investigated as a treatment for asthma.

Waktu Paruh-
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Homatropine Approved DB11181
small molecule | CAS: 87-00-3

Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic r…

Kategori:
AlkaloidsAnticholinergic AgentsAutonomic Agents +8
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Homatropine methylbromide Approved DB00725
small molecule | CAS: 80-49-9

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAlkaloids +7
Target Protein:
Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M4 +2
Waktu Paruh-
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Genetik -
Homidium DB17031
small molecule | CAS: 3546-21-2

Homidium is a group II compound with trypanocidal effects.[A253017]

Kategori:
Anti-Infective AgentsAnticholinergic AgentsAntiparasitic Agents +14
Waktu Paruh-
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Genetik -
small molecule | CAS: 848-53-3

Deskripsi belum tersedia.

Kategori:
Piperazines
Waktu Paruh-
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Homocysteine DB04422
small molecule | CAS: 6027-13-0

Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1
Target Protein:
S-ribosylhomocysteine lyase5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase5-methyltetrahydrofolate S-homocysteine methyltransferase
Waktu Paruh-
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Genetik -
small molecule | CAS: 451-13-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicPhenylacetates
Target Protein:
Penicillin G acylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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