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11793

Total database: 17430
Struktur (SMILES)
8607 (73.0%)
Target
6418 (54.4%)
Genomik
102 (0.9%)
Referensi
11793 (100.0%)

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Hasil Pencarian (11793)

Halaman 115 / 236
Hexachlorophene Approved DB00756
small molecule | CAS: 70-30-4

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorder…

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalAntiseptics and Disinfectants +8
Target Protein:
D-lactate dehydrogenaseSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialGlutamate dehydrogenase 1, mitochondrial +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hexadecanal DB03381
small molecule | CAS: 629-80-1

Deskripsi belum tersedia.

Target Protein:
RhodopsinAcyl-CoA-binding protein
Waktu Paruh-
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Genetik -
small molecule | CAS: 86855-26-7

Deskripsi belum tersedia.

Kategori:
Fatty AcidsLipidsPalmitic Acids +1
Target Protein:
Palmitoyl-protein thioesterase 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hexamethonium DB08960
small molecule | CAS: 60-26-4

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hyp…

Kategori:
AminesAnticholinergic AgentsAntihypertensive Agents +14
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Dihydroorotate dehydrogenase (quinone), mitochondrial
Waktu Paruh-
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Genetik -
small molecule | CAS: 124-09-4

Deskripsi belum tersedia.

Kategori:
AminesAmphetaminesEthylamines +3
Target Protein:
Carbonic anhydrase 4Carbonic anhydrase 1Carbonic anhydrase 6 +4
Waktu Paruh-
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Genetik -
Hexaminolevulinate Approved DB06261
small molecule | CAS: 140898-97-1

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approv…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsCarbon Radioisotopes +5
Waktu ParuhBiphasic eliminatio…
Vol. Distribusi-
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Genetik -
Hexane-1,6-Diol DB02210
small molecule | CAS: 629-11-8

Deskripsi belum tersedia.

Target Protein:
Phospholipase A2Glucocorticoid receptorGTPase HRas +3
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hexanoyl-CoA DB02563
small molecule | CAS: 5060-32-2

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
Enoyl-CoA hydratase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hexapeptide-2 DB18238
biotech | CAS: 87616-84-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsGrowth Hormone-Releasing HormonePeptides
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hexapropymate DB13662
small molecule | CAS: 358-52-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCentral Nervous System DepressantsHypnotics and Sedatives +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 34367-89-0

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesInositol Phosphates +2
Waktu Paruh-
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Genetik -
Hexestrol DB07931
small molecule | CAS: 84-16-2

A synthetic estrogen that has been used as a hormonal antineoplastic agent.

Kategori:
Antineoplastic AgentsAntineoplastic Agents, HormonalBenzene Derivatives +11
Target Protein:
Aldo-keto reductase family 1 member C1Estrogen receptorNuclear receptor subfamily 1 group I member 2 +1
Waktu Paruh-
Vol. Distribusi-
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Hexetidine Approved DB08958
small molecule | CAS: 141-94-6

A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

Kategori:
Alimentary Tract and MetabolismAnti-Infective AgentsAnti-Infective Agents, Local +6
Waktu Paruh-
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Genetik -
Hexobarbital DB01355
small molecule | CAS: 56-29-1

A barbiturate that is effective as a hypnotic and sedative.

Kategori:
AdjuvantsAnestheticsAnesthetics, General +18
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-4 +7
Waktu Paruh-
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Hexobendine Approved DB13265
small molecule | CAS: 54-03-5

Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478].

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Waktu Paruh-
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Hexocyclium Approved DB06787
small molecule | CAS: 6004-98-4

Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. Proton pump inhibitors lik…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAnticholinergic Agents +3
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2 +1
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
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Hexylresorcinol Approved DB11254
small molecule | CAS: 136-77-6

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid …

Kategori:
AnthelminticsAnti-Infective AgentsAnti-Infective Agents, Local +6
Target Protein:
TyrosinaseDNA topoisomerase 1Protein-glutamine gamma-glutamyltransferase 2
Waktu ParuhReadily accessible …
Vol. DistribusiReadily accessible …
KlirensReadily accessible …
Genetik -
HG004 DB18666
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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Hidrosmin DB13490
small molecule | CAS: 115960-14-0

Deskripsi belum tersedia.

Kategori:
BenzopyransCapillary Stabilizing AgentsChromones +5
Waktu Paruh-
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Genetik -
Higenamine DB12779
small molecule | CAS: 5843-65-2

Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-Agonists +17
Waktu Paruh-
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Hiltonol DB17293
biotech | CAS: 59789-29-6

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAmino AcidsAmino Acids, Basic +17
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hippuric acid DB16842
small molecule | CAS: 495-69-2

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +3
Waktu Paruh-
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Genetik -
Hispidulin DB14008
small molecule | CAS: 1447-88-7

Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties [A32513].

Kategori:
BenzopyransChromonesFlavonoids +2
Waktu Paruh-
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Histamine Approved DB05381
small molecule | CAS: 51-45-6

A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Kategori:
Adjuvants, ImmunologicAminesAntineoplastic and Immunomodulating Agents +19
Target Protein:
Histamine H1 receptorHistamine H2 receptorHistamine H3 receptor +2
Waktu Paruh-
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Genetik -
small molecule | CAS: 1464897-15-1

Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).

Kategori:
AminesAnti-Asthmatic AgentsAutacoids +6
Waktu Paruh-
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Genetik -
Histrelin Approved DB06788
small molecule | CAS: 76712-82-8

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher pot…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +17
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe apparent volume…
KlirensIn prostate cancer …
Genetik -
small molecule | CAS: 729607-74-3

HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +5
Waktu Paruh-
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Genetik -
HL001 DB18026
small molecule | CAS: 1186371-31-2

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
HLX-58 DB18699
biotech

HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.

Waktu Paruh-
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HLX70 DB16509
biotech

HLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics in healthy adult volunteers. The condition …

Kategori:
Experimental Unapproved Treatments for COVID-19
Waktu Paruh-
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Genetik -
HM-30181 DB14070
small molecule | CAS: 849675-66-7

Deskripsi belum tersedia.

Kategori:
ATP Binding Cassette Transporter, Subfamily B, Member 1, antagonists & inhibitorsHeterocyclic Compounds, Fused-RingP-glycoprotein inhibitors +1
Target Protein:
ATP-dependent translocase ABCB1Phosphatidylcholine translocator ABCB4
Waktu Paruh-
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Genetik -
HM15912 DB18266
biotech

HM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.

Waktu Paruh-
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HMI-103 DB17684
biotech

HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.

Waktu Paruh-
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HMR4011 DB06225
small molecule

HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. IPL 576,092 has previously been investigated as a treatment for asthma.

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HNM01 DB06531
biotech

The drug hNM01, a humanized monoclonal antibody developed by SRD Pharmaceuticals, Inc., targets the V(3) region of the HIV-1 envelope protein gp120, functioning as an HIV replication inhibitor. It entered Phase 1 clinical trials for the treatment of HIV infec…

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Homidium DB17031
small molecule | CAS: 3546-21-2

Homidium is a group II compound with trypanocidal effects.[A253017]

Kategori:
Anti-Infective AgentsAnticholinergic AgentsAntiparasitic Agents +14
Waktu Paruh-
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Genetik -
Homocysteine DB04422
small molecule | CAS: 6027-13-0

Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1
Target Protein:
S-ribosylhomocysteine lyase5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase5-methyltetrahydrofolate S-homocysteine methyltransferase
Waktu Paruh-
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Genetik -
Homosalate Approved DB11064
small molecule | CAS: 118-56-9

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet…

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Target Protein:
Progesterone receptorAndrogen receptorEstrogen receptor
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
small molecule | CAS: 1192-20-7

Deskripsi belum tersedia.

Kategori:
FuransLactonesLuminescent Proteins
Target Protein:
Sodium/hydrogen exchanger 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Honey Approved DB14242
biotech | CAS: 8028-66-8

Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
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Honeydew melon Approved DB10536
biotech

Honeydew melon allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
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Genetik -
Honokiol DB19283
small molecule | CAS: 35354-74-6

Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).

Kategori:
AlkenesAnti-Allergic AgentsAnti-Anxiety Agents +24
Target Protein:
Polyunsaturated fatty acid 5-lipoxygenaseProstaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Hopantenic acid DB14044
small molecule | CAS: 18679-90-8

Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115]

Kategori:
Acids, AcyclicAlanineAmino Acids +6
Waktu Paruh-
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Hops Approved DB10687
biotech

Hops allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityHerbs and Natural ProductsIncreased Histamine Release +2
Waktu Paruh-
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Hordeum vulgare pollen Approved DB10961
biotech

Hordeum vulgare pollen is the pollen of the Hordeum vulgare plant. Hordeum vulgare pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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Genetik -
Horseradish Approved DB10674
biotech

Horseradish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
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Genetik -
HOV-12020 DB17976
small molecule

HOV-12020 is a palm tocotrienols complex being investigated for the treatment of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).[L47271]

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HPA-23 DB17739
small molecule | CAS: 89899-81-0

HPA-23 is an investigational antiviral compound.[A259142]

Kategori:
Anti-Infective AgentsAntineoplastic AgentsAntiviral Agents +4
Waktu Paruh-
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Genetik -
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